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作者:Gomez-Marin, Alex
作者单位:Universidad Miguel Hernandez de Elche; Consejo Superior de Investigaciones Cientificas (CSIC)
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作者:Chakradhar, Shraddha
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作者:Voosen, Paul
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作者:Bishop, Janice L.; Lane, Melissa D.
作者单位:SETI Institute
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作者:Callegari, Sylvie; Kirk, Nicholas S.; Gan, Zhong Yan; Dite, Toby; Cobbold, Simon A.; Leis, Andrew; Dagley, Laura F.; Glukhova, Alisa; Komander, David
作者单位:Walter & Eliza Hall Institute; University of Melbourne; University of Melbourne; Monash University; Monash University
摘要:Mutations in the ubiquitin kinase PINK1 cause early-onset Parkinson's disease, but how PINK1 is stabilized at depolarized mitochondrial translocase complexes has remained poorly understood. We determined a 3.1-angstrom resolution cryo-electron microscopy structure of dimeric human PINK1 stabilized at an endogenous array of mitochondrial translocase of the outer membrane (TOM) and voltage-dependent anion channel (VDAC) complexes. Symmetric arrangement of two TOM core complexes around a central ...
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作者:Chakradhar, Shraddha
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作者:Wright, William J.; Hedrick, Nathan G.; Komiyama, Takaki
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasticity in vivo during learning and whether these rules are uniform within individual neurons remain unclear. Using in vivo longitudinal imaging with single-synapse resolution in the mouse motor cortex during motor learning, we found that apical and basal dendrites of layer 2/3 (L2/3) pyramidal neuro...
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作者:Nguyen, Phuong X.; Ma, Liguo; Chaturvedi, Raghav; Watanabe, Kenji; Taniguchi, Takashi; Shan, Jie; Mak, Kin Fai
作者单位:Cornell University; National Institute for Materials Science; Cornell University
摘要:Excitonic insulators (EIs) are a solid-state prototype for bosonic phases of matter that can support charge-neutral exciton currents. However, demonstration of exciton transport in EIs is difficult. In this work, we show that the strong interlayer excitonic correlation at equal electron and hole densities in MoSe2/WSe2 double layers separated by a 2-nanometer barrier yields perfect Coulomb drag under zero magnetic field: A charge current in one layer induces an equal but opposite drag current ...
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作者:Billard, Aude G.
作者单位:Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
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作者:Chandrashekhar, Vaishnavi