Science

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• Giant radar satellite set to probe Earth's shifts and shudders AI翻译
  作者：Greshko, Michael
• Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage AI翻译
  作者：Hoagland, Daisy A.; Rodriguez-Morales, Patricia; Mann, Alexander O.; Baez Vazquez, Alan Y.; Yu, Shuang; Lai, Alicia; Kane, Harry; Dang, Susanna M.; Lin, Yunkang; Thorens, Louison; Begum, Shahinoor; Castro, Martha A.; Pope, Scott D.; Lim, Jaechul; Li, Shun; Zhang, Xian; Li, Ming O.; Kim, Carla F.; Jackson, Ruaidhri; Medzhitov, Ruslan; Franklin, Ruth A.
  作者单位：Harvard University; Harvard University; Harvard Medical School; Yale University; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Northeastern University; Memorial Sloan Kettering Cancer Center; Harvard University; Howard Hughes Medical Institute; Yale University
  摘要：Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the pathological effects of type I interferon (IFN-I) during infection and damage in mice. At baseline, OSM-deficient mice exhibited altered alveolar type II (ATII) epithelial cell states. In response to influenza or viral mimic challenge, mice lacking OSM exhibited heightened IFN-I responses and increased...
• Electronically diverse carbenes Metal carbenes with different polarities are generated from a single class of precursor AI翻译
  作者：Charette, Andre B.
  作者单位：Universite de Montreal
• Auditors can't save carbon offsets AI翻译
  作者：Giles, Cynthia; Coglianese, Cary
  作者单位：University of Pennsylvania; University of Pennsylvania; University of Pennsylvania
• Replacing microglia to treat a brain disease AI翻译
  作者：Du, Siling; Kipnis, Jonathan
  作者单位：Washington University (WUSTL); Washington University (WUSTL)
• Glymphatic dysfunction in Alzheimer's disease: A critical appraisal AI翻译
  作者：Keil, Samantha A.; Jansson, Deidre; Braun, Molly; Iliff, Jeffrey J.
  作者单位：University of Washington; University of Washington Seattle; US Department of Veterans Affairs; Veterans Health Administration (VHA); Vet Affairs Puget Sound Health Care System; Cornell University; Weill Cornell Medicine; University System of Georgia; Augusta University; University of Washington; University of Washington Seattle
  摘要：Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer's disease (AD). Our understanding of glymphatic function and its involvement in the pathogenesis of AD derives primarily from correlative clinical data and rodent studies. A causal role for glymphatic dysfunction in AD has not yet been established in humans. We review current approaches to assess glymphatic function clinically, which capture different f...
• Overturning circulation structures the microbial functional seascape of the South Pacific AI翻译
  作者：Kolody, Bethany C.; Sachdeva, Rohan; Zheng, Hong; Fuessy, Zoltan; Tsang, Eunice; Sonnerup, Rolf E.; Purkey, Sarah G.; Allen, Eric E.; Banfield, Jillian F.; Allen, Andrew E.
  作者单位：University of California System; University of California San Diego; Scripps Institution of Oceanography; J. Craig Venter Institute; University of California System; University of California Berkeley; University of Washington; University of Washington Seattle; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Monash University
  摘要：Global overturning circulation partitions the deep ocean into regions, each with different physicochemical characteristics, but the extent to which these water masses represent distinct ecosystems remains unknown. In this work, we integrate extensive genomic information with hydrography and water mass age to delineate microbial taxonomic and functional boundaries across the South Pacific. Prokaryotic richness steeply increases with depth in the surface ocean, which forms a so-called phylocline...
• Stable and uniform self-assembled organic diradical molecules for perovskite photovoltaics AI翻译
  作者：Wu, Wenping; Gao, Han; Jia, Lingbo; Li, Yuan; Zhang, Dezhong; Zhan, Hongmei; Xu, Jianan; Li, Binhe; Geng, Ziran; Cheng, Yanxiang; Tong, Hui; Pan, Yanxiong; Liu, Jun; He, Yongcai; Xu, Xixiang; Li, Zhenguo; He, Bo; Zhou, Min; Wang, Lixiang; Qin, Chuanjiang
  作者单位：Chinese Academy of Sciences; Changchun Institute of Applied Chemistry, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; Changchun Institute of Applied Chemistry, CAS; South China University of Technology
  摘要：Organic self-assembled molecules (SAMs), which are widely used in perovskite solar cells (PSCs), should exhibit enhanced performance to support the ongoing advancement of perovskite photovoltaics. We designed diradical SAMs through a coplanar conjugation of a donor-acceptor strategy to facilitate hole transport across the SAMs. The diradical SAMs exhibited high photothermal and electrochemical stability as well as improved assembly uniformity and large-area solution processability attributed t...
• Scientists identify culprit behind biggest ever US honey bee die-off AI翻译
  作者：Thompson, Joanna
• A fish out of water AI翻译
  作者：Lius, Andrea
  作者单位：University of Washington; University of Washington Seattle