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作者:Gibney, Elizabeth
摘要:The melding of artificial intelligence and robotics could catapult both fields to new heights.
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作者:Owens, Brian
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作者:[Anonymous]
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作者:Xin, Weizhi; Huang, Bangdong; Chi, Ximin; Liu, Yuehua; Xu, Mengjiao; Zhang, Yuanyuan; Li, Xu; Su, Qiang; Zhou, Qiang
作者单位:Westlake University; Westlake Laboratory; Westlake University; Xiamen University
摘要:Gamma delta (gamma delta) T cells, a unique T cell subgroup, are crucial in various immune responses and immunopathology 1-3 . The gamma delta T cell receptor (TCR), which is generated by gamma delta T cells, recognizes a diverse range of antigens independently of the major histocompatibility complex 2 . The gamma delta TCR associates with CD3 subunits, initiating T cell activation and holding great potential in immunotherapy 4 . Here we report the structures of two prototypical human V gamma ...
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作者:Magda, Jules J.
作者单位:Utah System of Higher Education; University of Utah
摘要:Soft solids that swell with shifts in pressure, temperature and pH provide a way of detecting such changes in the fluid around the brain. The method could be used to determine other properties of fluids elsewhere in the body.
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作者:Mallapaty, Smriti
摘要:The transplant aims to prolong the the person's life and provides important lessons for physicians.
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作者:Tang, Hanchuan; Yang, Yueying; Liu, Zhen; Li, Wenlong; Zhang, Yipeng; Huang, Yizhou; Kang, Tianyu; Yu, Yang; Li, Na; Tian, Ye; Liu, Xurui; Cheng, Yifan; Yin, Zhouping; Jiang, Xiaobing; Chen, Xiaodong; Zang, Jianfeng
作者单位:Huazhong University of Science & Technology; Huazhong University of Science & Technology; Nanyang Technological University; Huazhong University of Science & Technology; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Materials Research & Engineering (IMRE); Huazhong University of Science & Technology; Huazhong University of Science & Technology
摘要:Direct and precise monitoring of intracranial physiology holds immense importance in delineating injuries, prognostication and averting disease1. Wired clinical instruments that use percutaneous leads are accurate but are susceptible to infection, patient mobility constraints and potential surgical complications during removal2. Wireless implantable devices provide greater operational freedom but include issues such as limited detection range, poor degradation and difficulty in size reduction ...
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作者:van den Bedem, Henry
作者单位:University of California System; University of California San Francisco
摘要:Uptake of ammonium ions by marine microorganisms called archaea is a key first step in the conversion of ammonium to nitrogen found in ecosystems. Structural evidence reveals how archaea capture ammonium in an efficient way.
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作者:Reglade, U.; Bocquet, A.; Gautier, R.; Cohen, J.; Marquet, A.; Albertinale, E.; Pankratova, N.; Hallen, M.; Rautschke, F.; Sellem, L. -A.; Rouchon, P.; Sarlette, A.; Mirrahimi, M.; Campagne-Ibarcq, P.; Lescanne, R.; Jezouin, S.; Leghtas, Z.
作者单位:Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Ecole Normale Superieure de Lyon (ENS de LYON)
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作者:Luo, Qingyu; Raulston, Evangeline G.; Prado, Miguel A.; Wu, Xiaowei; Gritsman, Kira; Whalen, Karley S.; Yan, Kezhi; Booth, Christopher A. G.; Xu, Ran; van Galen, Peter; Doench, John G.; Shimony, Shai; Long, Henry W.; Neuberg, Donna S.; Paulo, Joao A.; Lane, Andrew A.
作者单位:Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Instituto de Investigacion Sanitaria del Principado de Asturias (ISPA); Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard Medical School; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Tel Aviv University; Rabin Medical Center; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute
摘要:Phosphoinositide-3-kinase-gamma (PI3K gamma) is implicated as a target to repolarize tumour-associated macrophages and promote antitumour immune responses in solid cancers1-4. However, cancer cell-intrinsic roles of PI3K gamma are unclear. Here, by integrating unbiased genome-wide CRISPR interference screening with functional analyses across acute leukaemias, we define a selective dependency on the PI3K gamma complex in a high-risk subset that includes myeloid, lymphoid and dendritic lineages....