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作者:Ledford, Heidi
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作者:Plackett, Benjamin
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作者:Cui, Xi-Yang; Li, Zhu; Kong, Ziren; Liu, Yu; Meng, Hao; Wen, Zihao; Wang, Changlun; Chen, Junyi; Xu, Mengxin; Li, Yiyan; Gao, Jingyue; Zhu, Wenjia; Hao, Zhixin; Huo, Li; Liu, Shaoyan; Yang, Zhi; Liu, Zhibo
作者单位:Peking University; Changping Laboratory; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College Hospital; Peking Union Medical College; Peking University
摘要:Targeted radionuclide therapy, in which radiopharmaceuticals deliver potent radionuclides to tumours for localized irradiation, has addressed unmet clinical needs and improved outcomes for patients with cancer1-4. A therapeutic radiopharmaceutical must achieve both sustainable tumour targeting and fast clearance from healthy tissue, which remains a major challenge5,6. A targeted ligation strategy that selectively fixes the radiopharmaceutical to the target protein in the tumour would be an ide...
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作者:Maiolino, Roberto; Scholtz, Jan; Witstok, Joris; Carniani, Stefano; D'Eugenio, Francesco; de Graaff, Anna; Uebler, Hannah; Tacchella, Sandro; Curtis-Lake, Emma; Arribas, Santiago; Bunker, Andrew; Charlot, Stephane; Chevallard, Jacopo; Curti, Mirko; Looser, Tobias J.; Maseda, Michael V.; Rawle, Timothy D.; Rodriguez del Pino, Bruno; Willott, Chris J.; Egami, Eiichi; Eisenstein, Daniel J.; Hainline, Kevin N.; Robertson, Brant; Williams, Christina C.; Willmer, Christopher N. A.; Baker, William M.; Boyett, Kristan; DeCoursey, Christa; Fabian, Andrew C.; Helton, Jakob M.; Ji, Zhiyuan; Jones, Gareth C.; Kumari, Nimisha; Laporte, Nicolas; Nelson, Erica J.; Perna, Michele; Sandles, Lester; Shivaei, Irene; Sun, Fengwu
作者单位:University of Cambridge; University of Cambridge; University of London; University College London; Scuola Normale Superiore di Pisa; Max Planck Society; University of Hertfordshire; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Astrobiologia (INTA); University of Oxford; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; European Southern Observatory; University of Wisconsin System; University of Wisconsin Madison; Space Telescope Science Institute; National Research Council Canada; University of Arizona; Smithsonian Institution; University of California System; University of California Santa Cruz; University of Melbourne; University of Cambridge; Space Telescope Science Institute; University of Colorado System; University of Colorado Boulder
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作者:Le, Tian; Pan, Zhiming; Xu, Zhuokai; Liu, Jinjin; Wang, Jialu; Lou, Zhefeng; Yang, Xiaohui; Wang, Zhiwei; Yao, Yugui; Wu, Congjun; Lin, Xiao
作者单位:Westlake University; Westlake University; Westlake University; Westlake University; Beijing Institute of Technology; Beijing Institute of Technology; China Jiliang University; Beijing Institute of Technology; Westlake University
摘要:The interplay among frustrated lattice geometry, non-trivial band topology and correlation yields rich quantum states of matter in kagome systems(1,2). A series of recent members in this family, AV(3)Sb(5) (A=K, Rb or Cs), exhibit a cascade of symmetry-breaking transitions(3), involving the 3Q chiral charge ordering(4-8), electronic nematicity(9,10), roton pair density wave(11) and superconductivity(12). The nature of the superconducting order is yet to be resolved. Here we report an indicatio...
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作者:Alma, Andrea M.; Buteler, Micaela
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作者:[Anonymous]
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作者:Muenzner, Julia; Trebulle, Pauline; Agostini, Federica; Zauber, Henrik; Messner, Christoph B.; Steger, Martin; Kilian, Christiane; Lau, Kate; Barthel, Natalie; Lehmann, Andrea; Textoris-Taube, Kathrin; Caudal, Elodie; Egger, Anna-Sophia; Amari, Fatma; De Chiara, Matteo; Demichev, Vadim; Gossmann, Toni I.; Muelleder, Michael; Liti, Gianni; Schacherer, Joseph; Selbach, Matthias; Berman, Judith; Ralser, Markus
作者单位:Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Francis Crick Institute; University of Oxford; Wellcome Centre for Human Genetics; Helmholtz Association; Max Delbruck Center for Molecular Medicine; Swiss Institute of Allergy & Asthma Research; University of Zurich; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); Dortmund University of Technology; Institut Universitaire de France; Tel Aviv University; Max Planck Society
摘要:Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable discovery made in natural isolates of Saccharomyces cerevisiae is that aneuploidy-an imbalance in chromosome copy numbers-is frequent(1,2) (around 20%), which seems to contradict the substantial fitness costs and transient nature of aneuploidy when it is engineered in the laboratory(3-5). Here we generate a...
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作者:Garimella, Kiran; Chauchard, Simon
作者单位:Rutgers University System; Rutgers University New Brunswick; Universidad Carlos III de Madrid
摘要:A sample of roughly two million WhatsApp messages highlights urgent concerns about the spread and prevalence of AI-generated political content generated by artificial intelligence.
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作者:[Anonymous]