Nature

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• Adrenal cells provide clues to a parental-care puzzle AI翻译
  作者：Tollkuhn, Jessica
  作者单位：Cold Spring Harbor Laboratory
  摘要：Both parents of oldfield mice care for offspring, whereas in deer mice, mothers usually care for pups. The discovery of a type of adrenal-gland cell that is present in oldfield mice but not in deer mice helps to explain the difference.
• Genome organization around nuclear speckles drives mRNA splicing efficiency AI翻译
  作者：Bhat, Prashant; Chow, Amy; Emert, Benjamin; Ettlin, Olivia; Quinodoz, Sofia A.; Strehle, Mackenzie; Takei, Yodai; Burr, Alex; Goronzy, Isabel N.; Chen, Allen W.; Huang, Wesley; Ferrer, Jose Lorenzo M.; Soehalim, Elizabeth; Goh, Say-Tar; Chari, Tara; Sullivan, Delaney K.; Blanco, Mario R.; Guttman, Mitchell
  作者单位：California Institute of Technology; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; Princeton University
  摘要：The nucleus is highly organized, such that factors involved in the transcription and processing of distinct classes of RNA are confined within specific nuclear bodies1,2. One example is the nuclear speckle, which is defined by high concentrations of protein and noncoding RNA regulators of pre-mRNA splicing3. What functional role, if any, speckles might play in the process of mRNA splicing is unclear4,5. Here we show that genes localized near nuclear speckles display higher spliceosome concentr...
• Heed lessons from past studies involving transgender people: first, do no harm AI翻译
  作者：Kennis, Mathilde; Staicu, Robin; Dewitte, Marieke; T'Sjoen, Guy; Sack, Alexander T.; Duecker, Felix
  作者单位：Maastricht University; Maastricht University; Maastricht University; Ghent University; Ghent University Hospital; Ghent University; Ghent University Hospital; Maastricht University
  摘要：Decades of neuroscientific work have focused on exploring a biological basis for transgender identity - but researchers must take societal factors into account.
• Mapping model units to visual neurons reveals population code for social behaviour AI翻译
  作者：Cowley, Benjamin R.; Calhoun, Adam J.; Rangarajan, Nivedita; Ireland, Elise; Turner, Maxwell H.; Pillow, Jonathan W.; Murthy, Mala
  作者单位：Princeton University; Cold Spring Harbor Laboratory; Stanford University
  摘要：The rich variety of behaviours observed in animals arises through the interplay between sensory processing and motor control. To understand these sensorimotor transformations, it is useful to build models that predict not only neural responses to sensory input(1-5) but also how each neuron causally contributes to behaviour(6,7). Here we demonstrate a novel modelling approach to identify a one-to-one mapping between internal units in a deep neural network and real neurons by predicting the beha...
• Joint recycling of steel and cement cuts CO2 emissions AI翻译
  作者：Miller, Sabbie A.
  作者单位：University of California System; University of California Davis
  摘要：Cement can be reused by including it as a component of steel recycling. This opens the way to an industrial partnership that improves the use of materials and lowers carbon emissions - but only if waste resources are well managed.
• A myopia epidemic is sweeping the globe. Here's how to stop it AI翻译
  作者：Dolgin, Elie
  摘要：Time spent outdoors is the best defence against rising rates of short-sightedness, but scientists are searching for other ways to reverse the troubling trend.
• SEA URCHINS FALL APART AS TINY ASSASSIN STRIKES AI翻译
  作者：[Anonymous]
• Electric recycling of Portland cement at scale AI翻译
  作者：Dunant, Cyrille F.; Joseph, Shiju; Prajapati, Rohit; Allwood, Julian M.
  作者单位：University of Cambridge
  摘要：Cement production causes 7.5% of global anthropogenic CO2 emissions, arising from limestone decarbonation and fossil-fuel combustion(1-3). Current decarbonation strategies include substituting Portland clinker with supplementary materials, but these mainly arise in emitting processes, developing alternative binders but none yet promises scale, or adopting carbon capture and storage that still releases some emissions(4-8). However, used cement is potentially an abundant, decarbonated feedstock....
• Therapy selection gets AI assistance AI翻译
  作者：Eisenstein, Michael
• Osmosensor-mediated control of Ca2+ spiking in pollen germination AI翻译
  作者：Pei, Songyu; Tao, Qi; Li, Wenke; Qi, Guoning; Wang, Borong; Wang, Yan; Dai, Shiwen; Shen, Qiujing; Wang, Xi; Wu, Xiaomei; Xu, Shijian; Theprungsirikul, Lynn; Zhang, Jingyuan; Liang, Liang; Liu, Yuantao; Chen, Kena; Shen, Yang; Crawford, Bridget M.; Cheng, Mengjia; Zhang, Qi; Wang, Yiqi; Liu, Hongli; Yang, Benguang; Krichilsky, Bryan; Pei, Jessica; Song, Karen; Johnson, Douglas M.; Jiang, Zhonghao; Wu, Feihua; Swift, Gary B.; Yang, Huanghe; Liu, Zhonghua; Zou, Xuexiao; Vo-Dinh, Tuan; Liu, Feng; Pei, Zhen-Ming; Yuan, Fang
  作者单位：Hunan Agricultural University; Duke University; Duke University; Zhejiang University; Hangzhou Normal University; Duke University; Duke University; Duke University
  摘要：Higher plants survive terrestrial water deficiency and fluctuation by arresting cellular activities (dehydration) and resuscitating processes (rehydration). However, how plants monitor water availability during rehydration is unknown. Although increases in hypo-osmolarity-induced cytosolic Ca2+ concentration (HOSCA) have long been postulated to be the mechanism for sensing hypo-osmolarity in rehydration(1,2), the molecular basis remains unknown. Because osmolarity triggers membrane tension and...