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作者:Tollkuhn, Jessica
作者单位:Cold Spring Harbor Laboratory
摘要:Both parents of oldfield mice care for offspring, whereas in deer mice, mothers usually care for pups. The discovery of a type of adrenal-gland cell that is present in oldfield mice but not in deer mice helps to explain the difference.
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作者:Bhat, Prashant; Chow, Amy; Emert, Benjamin; Ettlin, Olivia; Quinodoz, Sofia A.; Strehle, Mackenzie; Takei, Yodai; Burr, Alex; Goronzy, Isabel N.; Chen, Allen W.; Huang, Wesley; Ferrer, Jose Lorenzo M.; Soehalim, Elizabeth; Goh, Say-Tar; Chari, Tara; Sullivan, Delaney K.; Blanco, Mario R.; Guttman, Mitchell
作者单位:California Institute of Technology; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; Princeton University
摘要:The nucleus is highly organized, such that factors involved in the transcription and processing of distinct classes of RNA are confined within specific nuclear bodies1,2. One example is the nuclear speckle, which is defined by high concentrations of protein and noncoding RNA regulators of pre-mRNA splicing3. What functional role, if any, speckles might play in the process of mRNA splicing is unclear4,5. Here we show that genes localized near nuclear speckles display higher spliceosome concentr...
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作者:Kennis, Mathilde; Staicu, Robin; Dewitte, Marieke; T'Sjoen, Guy; Sack, Alexander T.; Duecker, Felix
作者单位:Maastricht University; Maastricht University; Maastricht University; Ghent University; Ghent University Hospital; Ghent University; Ghent University Hospital; Maastricht University
摘要:Decades of neuroscientific work have focused on exploring a biological basis for transgender identity - but researchers must take societal factors into account.
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作者:Cowley, Benjamin R.; Calhoun, Adam J.; Rangarajan, Nivedita; Ireland, Elise; Turner, Maxwell H.; Pillow, Jonathan W.; Murthy, Mala
作者单位:Princeton University; Cold Spring Harbor Laboratory; Stanford University
摘要:The rich variety of behaviours observed in animals arises through the interplay between sensory processing and motor control. To understand these sensorimotor transformations, it is useful to build models that predict not only neural responses to sensory input(1-5) but also how each neuron causally contributes to behaviour(6,7). Here we demonstrate a novel modelling approach to identify a one-to-one mapping between internal units in a deep neural network and real neurons by predicting the beha...
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作者:Miller, Sabbie A.
作者单位:University of California System; University of California Davis
摘要:Cement can be reused by including it as a component of steel recycling. This opens the way to an industrial partnership that improves the use of materials and lowers carbon emissions - but only if waste resources are well managed.
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作者:Dolgin, Elie
摘要:Time spent outdoors is the best defence against rising rates of short-sightedness, but scientists are searching for other ways to reverse the troubling trend.
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作者:[Anonymous]
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作者:Dunant, Cyrille F.; Joseph, Shiju; Prajapati, Rohit; Allwood, Julian M.
作者单位:University of Cambridge
摘要:Cement production causes 7.5% of global anthropogenic CO2 emissions, arising from limestone decarbonation and fossil-fuel combustion(1-3). Current decarbonation strategies include substituting Portland clinker with supplementary materials, but these mainly arise in emitting processes, developing alternative binders but none yet promises scale, or adopting carbon capture and storage that still releases some emissions(4-8). However, used cement is potentially an abundant, decarbonated feedstock....
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作者:Eisenstein, Michael
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作者:Pei, Songyu; Tao, Qi; Li, Wenke; Qi, Guoning; Wang, Borong; Wang, Yan; Dai, Shiwen; Shen, Qiujing; Wang, Xi; Wu, Xiaomei; Xu, Shijian; Theprungsirikul, Lynn; Zhang, Jingyuan; Liang, Liang; Liu, Yuantao; Chen, Kena; Shen, Yang; Crawford, Bridget M.; Cheng, Mengjia; Zhang, Qi; Wang, Yiqi; Liu, Hongli; Yang, Benguang; Krichilsky, Bryan; Pei, Jessica; Song, Karen; Johnson, Douglas M.; Jiang, Zhonghao; Wu, Feihua; Swift, Gary B.; Yang, Huanghe; Liu, Zhonghua; Zou, Xuexiao; Vo-Dinh, Tuan; Liu, Feng; Pei, Zhen-Ming; Yuan, Fang
作者单位:Hunan Agricultural University; Duke University; Duke University; Zhejiang University; Hangzhou Normal University; Duke University; Duke University; Duke University
摘要:Higher plants survive terrestrial water deficiency and fluctuation by arresting cellular activities (dehydration) and resuscitating processes (rehydration). However, how plants monitor water availability during rehydration is unknown. Although increases in hypo-osmolarity-induced cytosolic Ca2+ concentration (HOSCA) have long been postulated to be the mechanism for sensing hypo-osmolarity in rehydration(1,2), the molecular basis remains unknown. Because osmolarity triggers membrane tension and...