Nature

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• peri-Fused polyaromatic molecular contacts for perovskite solar cells AI翻译
  作者：Zhao, Ke; Liu, Qingqing; Yao, Libing; Deger, Caner; Shen, Jiahui; Zhang, Xu; Shi, Pengju; Tian, Yuan; Luo, Yixin; Xu, Jiazhe; Zhou, Jingjing; Jin, Donger; Wang, Sisi; Fan, Wei; Zhang, Shaochen; Chu, Shenglong; Wang, Xiaonan; Tian, Liuwen; Liu, Ruzhang; Zhang, Li; Yavuz, Ilhan; Wang, Hong-fei; Yang, Deren; Wang, Rui; Xue, Jingjing
  作者单位：Zhejiang University; Zhejiang University; Westlake University; Westlake University; Marmara University; Yangzhou University; Westlake University; Baima Lake Laboratory; Westlake University; Westlake University; Westlake University
  摘要：Molecule-based selective contacts have become a crucial component to ensure high-efficiency inverted perovskite solar cells1-5. These molecules always consist of a conjugated core with heteroatom substitution to render the desirable carrier-transport capability6-9. So far, the design of successful conjugation cores has been limited to two N-substituted pi-conjugated structures, carbazole and triphenylamine, with molecular optimization evolving around their derivatives2,5,10-12. However, furthe...
• Highest ocean heat in four centuries places Great Barrier Reef in danger AI翻译
  作者：Henley, Benjamin J.; McGregor, Helen V.; King, Andrew D.; Hoegh-Guldberg, Ove; Arzey, Ariella K.; Karoly, David J.; Lough, Janice M.; DeCarlo, Thomas M.; Linsley, Braddock K.
  作者单位：University of Wollongong; University of Wollongong; University of Melbourne; University of Melbourne; University of Melbourne; University of Queensland; Australian Institute of Marine Science; University of Western Australia; University of Western Australia; Tulane University; Columbia University
  摘要：Mass coral bleaching on the Great Barrier Reef (GBR) in Australia between 2016 and 2024 was driven by high sea surface temperatures (SST)1. The likelihood of temperature-induced bleaching is a key determinant for the future threat status of the GBR2, but the long-term context of recent temperatures in the region is unclear. Here we show that the January-March Coral Sea heat extremes in 2024, 2017 and 2020 (in order of descending mean SST anomalies) were the warmest in 400 years, exceeding the ...
• Seventh patient 'cured' of HIV: why scientists are excited AI翻译
  作者：Mallapaty, Smriti
  摘要：A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus.
• Genetic continuity and change among the Indigenous peoples of California (vol 624, pg 122, 2023) AI翻译
  作者：Nakatsuka, Nathan; Holguin, Brian; Sedig, Jakob; Langenwalter, Paul E.; Carpenter, John; Culleton, Brendan J.; Garcia-Moreno, Cristina; Harper, Thomas K.; Martin, Debra; Martinez-Ramirez, Jupiter; Porcayo-Michelini, Antonio; Tiesler, Vera; Villapando-Canchola, M. Elisa; Valdes Herrera, Alejandro; Callan, Kim; Curtis, Elizabeth; Kearns, Aisling; Iliev, Lora; Lawson, Ann Marie; Mah, Matthew; Mallick, Swapan; Micco, Adam; Michel, Megan; Workman, J. Noah; Oppenheimer, Jonas; Qiu, Lijun; Zalzala, Fatma; Rohland, Nadin; Diaz, Jose Luis Punzo; Johnson, John R.; Reich, David
  作者单位：Harvard University; Harvard Medical School; Harvard University; University of California System; University of California Santa Barbara; Harvard University; Biola University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Nevada System of Higher Education (NSHE); University of Nevada Las Vegas; Universidad Autonoma de Yucatan; Howard Hughes Medical Institute; Harvard University; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
• Mechanisms of actin filament severing and elongation by formins AI翻译
  作者：Palmer, Nicholas J.; Barrie, Kyle R.; Dominguez, Roberto
  作者单位：University of Pennsylvania; University of Pennsylvania
  摘要：Humans express 15 formins that play crucial roles in actin-based processes, including cytokinesis, cell motility and mechanotransduction1,2. However, the lack of structures bound to the actin filament (F-actin) has been a major impediment to understanding formin function. Whereas formins are known for their ability to nucleate and elongate F-actin3-7, some formins can additionally depolymerize, sever or bundle F-actin. Two mammalian formins, inverted formin 2 (INF2) and diaphanous 1 (DIA1, enc...
• The cortical amygdala consolidates a socially transmitted long-term memory AI翻译
  作者：Liu, Zhihui; Sun, Wenfei; Ng, Yi Han; Dong, Hua; Quake, Stephen R.; Sudhof, Thomas C.
  作者单位：Stanford University; Howard Hughes Medical Institute; Stanford University; Stanford University; Stanford University; Chan Zuckerberg Initiative (CZI)
  摘要：Social communication guides decision-making, which is essential for survival. Social transmission of food preference (STFP) is an ecologically relevant memory paradigm in which an animal learns a desirable food odour from another animal in a social context, creating a long-term memory(1,2). How food-preference memory is acquired, consolidated and stored is unclear. Here we show that the posteromedial nucleus of the cortical amygdala (COApm) serves as a computational centre in long-term STFP me...
• Protein droplets spread to seal tight junctions AI翻译
  作者：Ludwig, Alexander
  作者单位：Nanyang Technological University; Nanyang Technological University
  摘要：Cells that form tissue barriers rely on cell-cell contacts called tight junctions. These structures assemble from protein condensates that spread along the cell membrane like a water droplet spreading over glass. Step-by-step formation of tight junctions between epithelial cells.
• HOW TO SPOT A PREDATORY CONFERENCE AI翻译
  作者：Ro, Christine
• Genetic links found to the world's biggest killer of new mothers AI翻译
  作者：[Anonymous]
  摘要：Genes associated with postpartum haemorrhage spotlight a hormone's role in dangerous bleeding after childbirth.
• Clonal inactivation of TERT impairs stem cell competition AI翻译
  作者：Hasegawa, Kazuteru; Zhao, Yang; Garbuzov, Alina; Corces, M. Ryan; Neuhofer, Patrick; Gillespie, Victoria M.; Cheung, Peggie; Belk, Julia A.; Huang, Yung-Hsin; Wei, Yuning; Chen, Lu; Chang, Howard Y.; Artandi, Steven E.
  作者单位：Stanford Cancer Institute; Stanford University; Stanford University; Stanford University; Fox Chase Cancer Center; Stanford University; Howard Hughes Medical Institute; Stanford University
  摘要：Telomerase is intimately associated with stem cells and cancer, because it catalytically elongates telomeres-nucleoprotein caps that protect chromosome ends(1). Overexpression of telomerase reverse transcriptase (TERT) enhances the proliferation of cells in a telomere-independent manner(2-8), but so far, loss-of-function studies have provided no evidence that TERT has a direct role in stem cell function. In many tissues, homeostasis is shaped by stem cell competition, a process in which stem c...