Nature

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• HOW CLOSE IS AI TO HUMAN-LEVEL INTELLIGENCE? AI翻译
  作者：Ananthaswamy, Anil
• ADMIT KNOWLEDGE GAPS TO WIN HEARTS AND MINDS AI翻译
  作者：[Anonymous]
• Anti-viral defence by an mRNA ADP-ribosyltransferase that blocks translation AI翻译
  作者：Vassallo, Christopher N.; Doering, Christopher R.; Laub, Michael T.
  作者单位：Massachusetts Institute of Technology (MIT); Howard Hughes Medical Institute
  摘要：Host-pathogen conflicts are crucibles of molecular innovation1,2. Selection for immunity to pathogens has driven the evolution of sophisticated immunity mechanisms throughout biology, including in bacterial defence against bacteriophages3. Here we characterize the widely distributed anti-phage defence system CmdTAC, which provides robust defence against infection by the T-even family of phages4. Our results support a model in which CmdC detects infection by sensing viral capsid proteins, ultim...
• How provinces and cities can sustain US-China climate cooperation AI翻译
  作者：Dai, Fan; Brown, Jerry; Xie, Zhenhua; Wang, Yi; Gong, Peng
  作者单位：University of Hong Kong; University of California System; University of California Berkeley; University of Hong Kong
• Polyclonal-to-monoclonal transition in colorectal precancerous evolution AI翻译
  作者：Lu, Zhaolian; Mo, Shanlan; Xie, Duo; Zhai, Xiangwei; Deng, Shanjun; Zhou, Kantian; Wang, Kun; Kang, Xueling; Zhang, Hao; Tong, Juanzhen; Hou, Liangzhen; Hu, Huijuan; Li, Xuefei; Zhou, Da; Lee, Leo Tsz On; Liu, Li; Zhu, Yaxi; Yu, Jing; Lan, Ping; Wang, Jiguang; He, Zhen; He, Xionglei; Hu, Zheng
  作者单位：Chinese Academy of Sciences; Shenzhen Institute of Advanced Technology, CAS; Chinese Academy of Sciences; Shenzhen Institute of Advanced Technology, CAS; University of Macau; Sun Yat Sen University; Xiamen University; Xiamen University; University of Macau; Sun Yat Sen University; Sun Yat Sen University; Sun Yat Sen University; Hong Kong University of Science & Technology; Sun Yat Sen University
  摘要：Unravelling the origin and evolution of precancerous lesions is crucial for effectively preventing malignant transformation, yet our current knowledge remains limited1, 2-3. Here we used a base editor-enabled DNA barcoding system4 to comprehensively map single-cell phylogenies in mouse models of intestinal tumorigenesis induced by inflammation or loss of the Apc gene. Through quantitative analysis of high-resolution phylogenies including 260,922 single cells from normal, inflamed and neoplasti...
• LIMITS ON FOREIGN STUDENTS WORRY UNIVERSITIES AI翻译
  作者：Mallapaty, Smriti
• Observation of Hilbert space fragmentation and fractonic excitations in 2D AI翻译
  作者：Adler, Daniel; Wei, David; Will, Melissa; Srakaew, Kritsana; Agrawal, Suchita; Weckesser, Pascal; Moessner, Roderich; Pollmann, Frank; Bloch, Immanuel; Zeiher, Johannes
  作者单位：Max Planck Society; Technical University of Munich; Max Planck Society; University of Munich
  摘要：The relaxation behaviour of isolated quantum systems taken out of equilibrium is among the most intriguing questions in many-body physics1. Quantum systems out of equilibrium typically relax to thermal equilibrium states by scrambling local information and building up entanglement entropy. However, kinetic constraints in the Hamiltonian can lead to a breakdown of this fundamental paradigm owing to a fragmentation of the underlying Hilbert space into dynamically decoupled subsectors in which th...
• Applied body-fluid analysis by wearable devices AI翻译
  作者：Brasier, Noe; Wang, Joseph; Gao, Wei; Sempionatto, Juliane R.; Dincer, Can; Ates, H. Ceren; Guder, Firat; Olenik, Selin; Schauwecker, Ivo; Schaffarczyk, Dietmar; Vayena, Effy; Ritz, Nicole; Weisser, Maja; Mtenga, Sally; Ghaffari, Roozbeh; Rogers, John A.; Goldhahn, Joerg
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; University of California System; University of California San Diego; California Institute of Technology; University of Freiburg; University of Freiburg; Technical University of Munich; Imperial College London; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Basel; University of Basel; Lucerne Cantonal Hospital; Ifakara Health Institute; University of Basel; Swiss Tropical & Public Health Institute; University of Basel; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Feinberg School of Medicine
  摘要：Wearable sensors are a recent paradigm in healthcare, enabling continuous, decentralized, and non- or minimally invasive monitoring of health and disease. Continuous measurements yield information-rich time series of physiological data that are holistic and clinically meaningful. Although most wearable sensors were initially restricted to biophysical measurements, the next generation of wearable devices is now emerging that enable biochemical monitoring of both small and large molecules in a v...
• Human antibodies offer broad inhibition against variable proteins of the malaria parasite AI翻译
  作者：Tran, Tuan M.
  作者单位：Indiana University System; Indiana University Indianapolis
• ANTIMATTER TO BE TRANSPORTED OUTSIDE A LAB FOR FIRST TIME - IN A VAN AI翻译
  作者：Gibney, Elizabeth