51期

最新文章

• Reviving Vavilov's vision: The tragedy of biodiversity governance and principles for reform AI翻译
  作者：Bertioli, David J.; Leal-Bertioli, Soraya C. M.; Erda, Tarikua; Simpson, Charles E.; Barrett, Scott; Raven, Peter H.
  作者单位：University System of Georgia; University of Georgia; University System of Georgia; University of Georgia; University System of Georgia; University of Georgia; New York University; Texas A&M University System; Texas A&M University College Station; Texas A&M AgriLife Research; Columbia University; Missouri Botanical Gardens
• Promoters of cooperation in evolutionary games AI翻译
  作者：Svoboda, Jakub; Chatterjee, Krishnendu
  作者单位：Institute of Science & Technology - Austria
  摘要：Evolutionary games provide a flexible mathematical framework for many problems in biology and social evolution. Prisoners' dilemma, and in particular, the important special case of donation games, represents social dilemmas where cooperation is mutually beneficial, yet defection is preferred by selfish agents. In evolutionary games on networks, the agents interact over a population structure. The existence of population structures that promote cooperative behavior is a fascinating and active r...
• Rising rates of wildfire building destruction in the conterminous United States AI翻译
  作者：Carlson, Amanda R.; Hawbaker, Todd J.; Mockrin, Miranda H.; Radeloff, Volker C.; Bair, Lucas S.; Caggiano, Michael D.; Meldrum, James R.; Alexandre, Patricia M.; Kramer, H. Anu; Steblein, Paul F.
  作者单位：United States Department of the Interior; United States Geological Survey; United States Department of Agriculture (USDA); United States Forest Service; University of Wisconsin System; University of Wisconsin Madison; United States Department of the Interior; United States Geological Survey; United States Department of Agriculture (USDA); United States Forest Service; United States Department of the Interior; United States Geological Survey; United States Department of the Interior; United States Geological Survey
  摘要：Many regions of the world have seen an increase in highly destructive wildfires, driven by well- documented increases in burned area and growth of housing in the wildland-urban interface (WUI), which exposes more homes to fire. However, it is unclear whether wildfires are also becoming more destructive due to changes in wildfire behavior or in the development patterns of exposed communities. Here, we assessed trends in wildfire building exposure and destruction rates in the conterminous United...
• Rapid morphological change in an urban bird due to COVID-19 restrictions AI翻译
  作者：Diamant, Eleanor S.; Yeh, Pamela J.
  作者单位：University of California System; University of California Los Angeles; The Santa Fe Institute
  摘要：The COVID-19 pandemic provided a natural experiment to test the impacts of human activity on urban-dwelling wildlife. Urban dark-eyed juncos differ in bill shape and size in Los Angeles in comparison to local wildlands. We measured juncos that hatched before, during, and after COVID-19 restrictions at a Los Angeles college campus. Birds that hatched during and soon after COVID-19 restrictions had bills that resembled those of local wildland birds. Yet, bills rapidly returned to pre-COVID-19 mo...
• The COVID-19 pandemic had heterogeneous effects on migration dynamics AI翻译
  作者：Klein, Jordan D.; Weber, Ingmar
  作者单位：Max Planck Society; Saarland University
• Reply to Loh: Evaluating anger as a mediator of criticism's effect on social media engagement using the interventional effects approach AI翻译
  作者：Lee, Jonathan Y.
  作者单位：Stanford University; Stanford Medicine
• High-speed X-ray tomography for 4D imaging AI翻译
  作者：Grega, Ivan; Whitney, William; Deshpande, Vikram Sudhir
  作者单位：University of Cambridge; Alphabet Inc.; DeepMind
  摘要：Capturing high-rate spatiotemporal deformation of materials in three dimensions (3D) remains a significant challenge with current X-ray imaging techniques. We present a methodology that combines advances in neural rendering techniques with volume correlation methods to accurately reconstruct complex, high-rate 3D spatiotemporal structural evolutions. The fidelity and versatility of the method, which requires no pretraining, are demonstrated for a diverse set of intricate 3D-printed microarchit...
• Interstep compatibility of a model for the prebiotic synthesis of RNA consistent with Hadean natural history AI翻译
  作者：Hirakawa, Yuta; Kim, Hyo-Joong; Furukawa, Yoshihiro; Abraham, Clay; Peng, Tzu-Wei; Biondi, Elisa; Benner, Steven A.
  作者单位：Tohoku University; Japan Agency for Marine-Earth Science & Technology (JAMSTEC)
  摘要：Models for prebiotic syntheses often have many steps, each separately validated by laboratory experiments. The challenge then asks whether these steps work together in natural geological environments, absent human intervention. Here, we analyze a proposed to be the first informational molecule to support Darwinian evolution, and life, on Earth and/or Mars. DSM requires that borate in multiple steps guide the formation of pentoses from simple carbohydrates and control phosphorylation, in all ca...
• Platelet- engineered CAR- T cells as adjuvant therapy after cancer surgery AI翻译
  作者：Wang, Yixin; Ogunnaike, Edikan; Yang, Huan; Yuan, Sichen; Hong, Rachel; Barrett, Allie; Ebong, Emem; Liu, Bo; Dotti, Gianpietro; Hu, Quanyin
  作者单位：University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison; University of North Carolina; University of North Carolina Chapel Hill; Emory University; University System of Georgia; Georgia Institute of Technology; University of Wisconsin System; University of Wisconsin Madison; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
  摘要：Surgery remains the mainstay treatment for many kinds of solid tumors, while tumor recurrence frequently occurs. Adjuvant therapy can reduce the risk of recurrence and improve the prognosis of surgery. Chimeric antigen receptor (CAR)-T cell therapy can be leveraged as an alternative adjuvant therapy to clear residual cancer cells and prevent tumor recurrence. However, systemic administration of CAR-T often results in insufficient tumor infiltration and side effects to normal organs. Given that...
• Asymmetrical recognition and processing of double- strand breaks formed during DNA replication AI翻译
  作者：Johnson, Matthew J.; Kimble, Michael T.; Jeong, Seoyeon; Sane, Aakanksha; Symington, Lorraine S.
  作者单位：Columbia University; Cornell University; Columbia University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; Columbia University; Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital
  摘要：DNA end resection to generate 3 ' single-stranded DNA (ssDNA) overhangs is the first step in homology-directed mechanisms of double-strand break (DSB) repair. While end resection has been extensively studied in the repair of endonuclease-induced DSBs, little is known about how resection proceeds at DSBs generated during DNA replication. We previously established a system to generate replication-dependent double-ended DSBs at the sites of nicks induced by the Cas9D10A nickase in the budding yea...