13期

最新文章

• Versatile artificial muscles by decoupling anisotropy AI翻译
  作者：Weissman, Eric; Khatavkar, Rohan; Sun, Jiefeng
  作者单位：Arizona State University; Arizona State University-Tempe
  摘要：Artificial muscles offer unique advantages for robotics, but their inability to adapt to diverse scenarios significantly limits their widespread application. We present the helical anisotropically reinforced polymer actuator (HARP)-a versatile class of artificial muscles. The HARP not only exhibits state-of-the-art performance (contraction ratios up to 75%, power densities of 1.93 kW/kg, and energy efficiencies of 29%) but also possesses a broad and decoupled design space, i.e., the anisotropy...
• DIRAS2 modulates MAPK pathway-mediated ferroptosis to regulate excitation/inhibition balance and seizure susceptibility AI翻译
  作者：Zhang, Chenlu; Hu, Liqin; Zhang, Hui; Yang, Min; Zhang, Yuansong; Zhang, Ningning; Xu, Yuanhang; Zhao, Yuping; Ren, Lingxin; Guo, Haokun; Li, Wei; Wang, Xuefeng; Yang, Yong; Tian, Xin
  作者单位：Shanxi Medical University; Chongqing Medical University; Chongqing Medical University; Chongqing Medical University; Chongqing Medical University; Hunan University; Lanzhou University; Lanzhou University; North Sichuan Medical University; Qingdao University
  摘要：Epilepsy is a common neurological disorder that is widely believed to be associated with GTPase, has not been well understood regarding its role and function within the nervous system. In this study, we found that DIRAS2 is downregulated in the hippocampus during the epileptogenesis phase in a kainic acid- induced epilepsy model, while it is upregulated during the chronic phase in this epilepsy model and in patients with tibility and activity, whereas knockdown of DIRAS2 has an opposite effect...
• Cell type diversification and phenotype convergence underlying white fin- ornamentation of cyprinid fishes AI翻译
  作者：Huang, Delai; Liu, Tiffany; Carr, August A.; de Mello, Pietro H.; Liang, Yipeng; Shriver, Leah P.; Chauvigne, Francois; Stephen, L.; Cerda, Joan; Patti, Gary J.; Parichy, David M.
  作者单位：University of Virginia; Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); CSIC - Centro Mediterraneo de Investigaciones Marinas y Ambientales (CMIMA); Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Ciencias del Mar (ICM); Autonomous University of Barcelona; Washington University (WUSTL); University of Virginia; Zhejiang University; University of Virginia (UVA) Health System; University of Virginia
  摘要：Neural crest-derived cells offer valuable opportunities to dissect mechanisms of cell fate specification and differentiation and the underpinnings of cell type diversification over evolutionary time. Particularly useful for such analyses are pigment cells of ectothermic vertebrates that arise from neural crest cells or via latent neural crest-derived stem cells. Among these are white cells, leucophores, present in a variety of species that contribute to patterns on the body or ornamentation on...
• Functionally heterogeneous intratumoral CD4+CD8+ double-positive T cells can give rise to single-positive T cells (vol 123, e2506168123, 2026) AI翻译
  作者：Li, Tony
• Fibro-adipogenic progenitor cells from murine SMA muscles are intrinsically adipogenic AI翻译
  作者：Luo, Yangyi E.; Abe-Teh, Zoe; Alsaghir, Tarek; Heiden, Katie D.; Basso, Kari B.; Barton, Elisabeth R.
  作者单位：State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida
  摘要：Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in the SMN1 gene. Although classically viewed as a neurogenic disease, SMA patients exhibit poor skeletal muscle regeneration and increased fatty-fibrotic infiltration. Fibro-adipogenic progenitors (FAPs) are mesenchymal precursor cells that contribute to muscle remodeling and underlie fat and fibrosis formation. Because FAPs transiently express Smn1 during regeneration, FAPs were examined in muscles from adult C...
• Mineral-facilitated aqueous synthesis of hydrogen cyanide from prebiotically abundant amino acids for chemical evolution AI翻译
  作者：Yang, Zening; Li, Yamei; Kitadai, Norio; Yamamoto, Masahiro; Ueno, Yuichiro; Lu, Yanjing; Li, Ailong; Adachi, Kiyohiro; Yamaguchi, Akira; Hashizume, Daisuke; Nakamura, Ryuhei
  作者单位：Institute of Science Tokyo; RIKEN; Japan Agency for Marine-Earth Science & Technology (JAMSTEC); RIKEN; Institute of Science Tokyo; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS
  摘要：Recent advances in prebiotic chemistry suggest that hydrogen cyanide (HCN) serves as a fundamental precursor for nearly all essential biomolecules and protometabolic processes for life's emergence. Although prevailing models of endogenous cyanide production rely on atmospheric methane, the availability of methane remains uncertain. Unlike methane, amino acids were likely prebiotically abundant, forming through multiple synthetic pathways under a methane-free, nonreducing atmosphere. Here, we d...
• Reply to Suetsugu and Johnson: Bird dispersal of berry-like yam bulbils is consistent with Batesian mimicry under low receiver cost AI翻译
  作者：Chomicki, Guillaume; Chen, Zhi; Li, Ying; Peng, Xingrong; Chen, Gao
  作者单位：Durham University; Chinese Academy of Sciences; Kunming Institute of Botany, CAS; Chinese Academy of Sciences; Kunming Institute of Botany, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Kunming Institute of Botany, CAS
• Genomic epidemiology of Salmonella and Campylobacter in poultry production: Quantifying the contribution of primary breeders AI翻译
  作者：Lipman, David J.
  作者单位：Stanford Medicine; Stanford University; Johns Hopkins University; Johns Hopkins University
  摘要：The US broiler production system processes over 9.3 billion chickens annually through a highly integrated pyramid structure where two primary breeding companies supply genetic stock to approximately 40 major integrators operating nationwide. To provide a quantitative, system- wide estimate of contamination origins, I analyzed whole- genome sequences from Salmonella and Campylobacter isolates collected from over 800 processing facilities as part of the United States Department of Agriculture's ...
• Giant photorefractive and photoexpansion effects in a van der Waals semiconductor AI翻译
  作者：Minnekhanov, Anton A.; Ermolaev, Georgy A.; Tsapenko, Alexey P.; Fradkin, Ilia M.; Tselikov, Gleb I.; Toksumakov, Adilet N.; Slavich, Aleksandr S.; Mazitov, Arslan B.; Smirnov, Sergey A.; Orekhov, Nikita D.; Kruglov, Ivan A.; Ivanov, Sergei A.; Radko, Ilya P.; Vyshnevyy, Andrey A.; Arsenin, Aleksey, V; Novoselov, Kostya S.; Volkov, Valentyn S.
  作者单位：University of Manchester; National University of Singapore; Institute for Functional Intelligent Materials (I-FIM); National University of Singapore
  摘要：Nanophotonics relies on precise nanoscale structuring, yet conventional fabrication techniques remain complex and costly. Layered van der Waals (vdW) materials, with their intrinsic anisotropy and high refractive indices, offer a promising route toward simplified nanostructuring and tunable optical functionality. However, no vdW material has previously been shown to exhibit a strong photorefractive effect-a key requirement for light-based modulation. Here, we report a giant photorefractive res...
• A conserved ethylene-triggered cell death mechanism may underlie hollow stem formation across plant species AI翻译
  作者：Yan, Mengxiao; Fan, Weijuan; Meng, Yinghui; Zhao, Jiamin; Yang, Wei; Xu, Ziyin; Gao, Yusen; Zhuang, Haiyan; Zhou, Wuyu; Wang, Yuqin; Huang, Qingjun; Yuan, Ling; Wang, Hongxia; Yang, Jun
  作者单位：Chinese Academy of Sciences; Shanghai Institute of Technology; Shanghai Normal University; Chinese Academy of Sciences; Center for Excellence in Molecular Plant Sciences, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Kentucky; University of Kentucky
  摘要：Hollow stems have independently evolved multiple times across the plant kingdom and play crucial roles in plant development and various environmental adaptations. However, the mechanisms underlying stem hollowness remain poorly understood. Water spinach (Ipomoea aquatica) is one of the few hollow-stemmed plants in the Convolvulaceae family (eudicot: asterid), and its hollow stems are essential for thriving in aquatic environments. Using histochemical staining and transcriptome analysis, we fou...