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作者:Thorp, H. Holden
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作者:Xue, Haoran; Saltini, Marco; Illing, Nicola; Shepherd, Kelly; Page-Macdonald, Olivia; Marketos, Oliver; Robertson, Caroline; Shankar, Anand; Suss, Sarah; Kappel, Christian; Alseekh, Saleh; Deinum, Eva E.; Ingle, Robert A.; Lenhard, Michael
作者单位:University of Potsdam; Wageningen University & Research; University of Cape Town; Max Planck Society
摘要:How genes determine the development of chiral structures is a fascinating question. The reciprocal placement of female and male organs on opposite sides of mirror-image flowers promotes efficient cross-pollination. Here, we identified that in butterfly lilies, female and male organs deflect by a combination of genetically controlled chirality and gravitropism, orienting left and right with respect to an external rather than internal reference axis. We found coordinated organ placement to be co...
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作者:Kraft, Fabian B.; Gehringer, Matthias
作者单位:Eberhard Karls University of Tubingen; Eberhard Karls University Hospital; Eberhard Karls University of Tubingen; Eberhard Karls University of Tubingen
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作者:Shultz, Zachary P.; Lee-Sam, Ansar; Chang, Yun-Pu; Sun, Luxin; Grassie, Dylan; Gabellini, Alessio; Pedretty, Kyle; Scattolin, Thomas; Izumi, Victoria; Fang, Bin; Sansil, Samer; Kakumanu, Ramu; Wojtas, Lukasz; Koomen, John; Schonbrunn, Ernst; Monastyrskyi, Andrii; Duckett, Derek; Lopchuk, Justin M.
作者单位:H Lee Moffitt Cancer Center & Research Institute; State University System of Florida; University of South Florida; H Lee Moffitt Cancer Center & Research Institute; H Lee Moffitt Cancer Center & Research Institute; H Lee Moffitt Cancer Center & Research Institute; State University System of Florida; University of South Florida
摘要:Covalent inhibition continues to gain momentum as a strategy for selective protein modulation in both therapeutic and chemical biology contexts. Covalent reactive groups (CRGs) typically engage nucleophilic residues such as cysteine, resulting in targeted protein inactivation. However, common electrophiles such as acrylamides often suffer from nonselective reactivity, leading to off-target effects and toxicity. To overcome these limitations, we developed a modular sulfur(IV) reagent platform f...
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作者:Kean, Sam
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作者:Wellerstein, Alex; Montgomery, Beronda L.; O'Mara, Margaret; Campos, Luis A.; Obasogie, Osagie K.; Conway, Erik M.
作者单位:Stevens Institute of Technology; Institut d'Etudes Politiques Paris (Sciences Po); Grinnell College; University of Washington; University of Washington Seattle; Rice University; University of California System; University of California Berkeley; Purdue University System; Purdue University
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作者:Oms, Thierry; Van Melderen, Laurence
作者单位:Universite Libre de Bruxelles
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作者:Dongarra, Jack; Reed, Daniel; Gannon, Dennis
作者单位:University of Tennessee System; University of Tennessee Knoxville; University of Manchester; Utah System of Higher Education; University of Utah; Indiana University System; Indiana University Bloomington
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作者:Kim, Cheongsan; Won, Jihyun; Kim, Donghyeon; Jung, Sohyun; Kim, Ho-Young; Hyun, Youbong
作者单位:Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); Daegu Gyeongbuk Institute of Science & Technology (DGIST)
摘要:Many plants explosively launch seeds, but these natural catapults often display inefficient, unpredictable energy transfer in seed ejection. Violets (Viola spp.) address this problem by ejecting seeds successively with consistent propulsive force from a single pod, a strategy that requires sophisticated energy release. In this work, we show that Viola achieves this feat with a simple and compact structure that generates adaptive force augmentation through sequential pinching. Our biological an...
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作者:Pardo, Jason D.; Mann, Arjan
作者单位:Field Museum of Natural History (Chicago)
摘要:Modern amphibians are characterized by an aquatic larval stage that ends abruptly with a period of widespread tissue remodeling (metamorphosis) upon transition to terrestrial adulthood. A transient larval stage ending in gradual metamorphosis is often assumed for the earliest digited tetrapods, but direct evidence of this larval stage is lacking. Exceptionally preserved stem tetrapod hatchlings show that a transient larval stage was absent in tetrapods both before and after the fin-to-limb tra...