3期

最新文章

• A discussion on the use of race in biomedical fields AI翻译
  作者：Hammonds, Evelynn M.
  作者单位：Harvard University; Harvard University
• Migration and sustainable development AI翻译
  作者：Adger, William Neil; Fransen, Sonja; de Campos, Ricardo Safra; Clark, William C.
  作者单位：University of Exeter; Maastricht University; Maastricht University; University of Exeter; Harvard University
  摘要：To understand the implications of migration for sustainable development requires a comprehensive consideration of a range of population movements and their feedback across space and time. This Perspective reviews emerging science at the interface of migration studies, demography, and sustainability, focusing on consequences of migration flows for nature-society interactions including on societal outcomes such as inequality; environmental causes and consequences of involuntary displacement; and...
• Scientific frontiers on migration and sustainability AI翻译
  作者：Adger, William Neil; Fransen, Sonja; de Campos, Ricardo Safra; Clark, William C.
  作者单位：University of Exeter; Maastricht University; Maastricht University; University of Exeter; Harvard University
• Three distinct kinetic groupings of the synaptotagmin family: Candidate sensors for rapid and delayed exocytosis (vol 102, pg 5210, 2005) AI翻译
  作者：Hui, Enfu; Bai, Jihong; Wang, Ping; Sugimori, Mutsuyuki; Llinas, Rodolfo R.; Chapman, Edwin R.
• Magnetism and metallicity in moiré transition metal dichalcogenides AI翻译
  作者：Tscheppe, Patrick; Zang, Jiawei; Klett, Marcel; Karakuzu, Seher; Celarier, Armelle; Cheng, Zhengqian; Marianetti, Chris A.; Maier, Thomas A.; Ferrero, Michel; Millis, Andrew J.; Schaefer, Thomas
  作者单位：Max Planck Society; Eberhard Karls University of Tubingen; Eberhard Karls University of Tubingen; Columbia University; Simons Foundation; Flatiron Institute; Institut Polytechnique de Paris; Ecole Polytechnique; Centre National de la Recherche Scientifique (CNRS); Columbia University; United States Department of Energy (DOE); Oak Ridge National Laboratory; Universite PSL; College de France
  摘要：The ability to control the properties of twisted bilayer transition metal dichalcogenides in situ makes them an ideal platform for investigating the interplay of strong correlations and geometric frustration. Of particular interest are the low energy scales, which make it possible to experimentally access both temperature and magnetic fields that are of the order of the bandwidth or the correlation scale. In this manuscript, we analyze the moire Hubbard model, believed to describe the low ener...
• Ryuzo Yanagimachi: Pioneer in fertilization and assisted reproductive biology technology AI翻译
  作者：Ward, Monika A.; Roberts, R. Michael; Ward, W. Steven
  作者单位：University of Hawaii System; University of Hawaii Manoa; University of Missouri System; University of Missouri Columbia; University of Hawaii System; University of Hawaii Manoa
• Migration, belonging, and the sustainability of atoll islands through a changing climate AI翻译
  作者：Jarillo, Sergio; Barnett, Jon
  作者单位：University of Melbourne
  摘要：Climate change might catalyze and exacerbate the trend of outmigration from low-lying atoll islands. There is speculation that migration away from atolls may not stop until such islands are abandoned. Yet migration creates both opportunities and risks for the sustainability of atoll communities. There is a trade-off between reduced demographic pressure on increasingly fragile atoll island environments and the financial and human resources necessary to adapt to climate change that can result fr...
• CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis AI翻译
  作者：Yuan, Youwen; Li, Kangli; Ye, Xueru; Wen, Shiyi; Zhang, Yanan; Teng, Fei; Zhou, Xuan; Deng, Yajuan; Yang, Xiaoyu; Wang, Weiwei; Lin, Jiayang; Luo, Shenjian; Zhang, Peizhen; Shi, Guojun; Zhang, Huijie
  作者单位：Southern Medical University - China; Southern Medical University - China; Southern Medical University - China; Army Medical University; Sun Yat Sen University; Sun Yat Sen University; Sun Yat Sen University
  摘要：Brown adipose tissue (BAT) is the main site of nonshivering thermogenesis which plays an important role in thermogenesis and energy metabolism. However, the regulatory factors that inhibit BAT activity remain largely unknown. Here, cardiotrophin-like cytokine factor 1 (CLCF1) is identified as a negative regulator of thermogenesis in BAT. Adenovirus-mediated overexpression of CLCF1 in BAT greatly impairs the thermogenic capacity of BAT and reduces the metabolic rate. Consistently, BAT-specific ...
• Academics are more specific, and practitioners more sensitive, in forecasting interventions to strengthen democratic attitudes AI翻译
  作者：Chua, James Y.; Voelkelb, Jan G.; Stagnaroc, Michael N.; Kang, Suji; Druckman, James N.; Rand, David G.; Willer, Robb
  作者单位：Columbia University; Stanford University; Massachusetts Institute of Technology (MIT); University of Pennsylvania; University of Rochester
  摘要：Concern over democratic erosion has led to a proliferation of proposed interventions to strengthen democratic attitudes in the United States. Resource constraints, however, prevent implementing all proposed interventions. One approach to identify promising interventions entails leveraging domain experts, who have knowledge regarding a given field, to forecast the effectiveness of candidate interventions. We recruit experts who develop general knowledge about a social problem (academics), exper...
• Control of cardiac contractions using Cre-lox and degron strategies in zebrafish AI翻译
  作者：Juan, Thomas; Bellec, Maeelle; Cardoso, Barbara; Athea, Heloise; Fukuda, Nana; Albu, Marga; Guenther, Stefan; Looso, Mario; Stainier, Didier Y. R.
  作者单位：Max Planck Society; German Centre for Cardiovascular Research; Max Planck Society; Max Planck Society
  摘要：Cardiac contractions and hemodynamic forces are essential for organ development and homeostasis. Control over cardiac contractions can be achieved pharmacologically or optogenetically. However, these approaches lack specificity or require direct access to the heart. Here, we compare two genetic approaches to control cardiac contractions by modulating the levels of the essential sarcomeric protein Tnnt2a in zebrafish. We first recombine a newly generated tnnt2a floxed allele using multiple line...