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作者：Leivada, Evelina; Guenther, Fritz; Dentella, Vittoria
作者单位：Autonomous University of Barcelona; Humboldt University of Berlin; Universitat Rovira i Virgili
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作者：Battey, Heather S.; Reid, Nancy
作者单位：Imperial College London; University of Toronto
摘要：The paper is concerned with inference for a parameter of interest in models that share a common interpretation for that parameter but that may differ appreciably in other respects. We study the general structure of models under which the maximum likelihood estimator of the parameter of interest is consistent under arbitrary misspecification of the nuisance part of the model. A specialization of the general results to matched-comparison and two-groups problems gives a more explicit and easily c...
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作者：Pain, Erwann; Snowden, Stuart; Oddy, Joseph; Shinhmar, Sonia; Alhammad, Yousef M. A.; King, Jason S.; Mueller-Taubenberger, Annette; Williams, Robin S. B.
作者单位：University of London; Royal Holloway University London; University of Geneva; University of Sheffield; University of Munich
摘要：Medium chain fatty acids are commonly consumed as part of diets for endurance sports and as medical treatment in ketogenic diets where these diets regulate energy metabolism and increase adenosine levels. However, the role of the equilibrative nucleoside transporter 1 (ENT1), which is responsible for adenosine transport across membranes in this process, is not well understood. Here, we investigate ENT1 activity in controlling the effects of two dietary medium chain fatty acids (decanoic and oc...
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作者：Thiagarajan, Nivedita; Lepland, Aivo; Ryb, Uri; Torsvik, Trond H.; Ainsaar, Leho; Hints, Olle; Eiler, John
作者单位：California Institute of Technology; Geological Survey of Norway; University of Tartu; Tallinn University of Technology; Hebrew University of Jerusalem; University of Oslo
摘要：The oxygen isotope ratio O-18/O-16 (expressed as a delta O-18(VSMOW) value) in marine sedimentary rocks has increased by similar to 8 parts per thousand from the early Paleozoic to modern times. Interpretation of this trend is hindered by ambiguities in the temperature of formation of the carbonate, the delta O-18(seawater), and the effects of postdepositional diagenesis. Carbonate clumped isotope measurements, a temperature proxy, offer constraints on this problem. This thermometer is thermod...
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作者：DeTomaso, Angela; Kim, Hyeyon; Shauh, Jacqueline; Adulla, Anika; Zigo, Sarah; Ghoul, Maya; Presicce, Pietro; Kallapur, Suhas G.; Goodman, Wendy; Tilburgs, Tamara; Way, Sing-Sing; Hackney, David; Moore, John; Mesiano, Sam
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作者：Harper, Dustin T.; Honisch, Barbel; Bowen, Gabriel J.; Zeebe, Richard E.; Haynes, Laura L.; Penman, Donald E.; Zachos, James C.
作者单位：Utah System of Higher Education; University of Utah; Columbia University; Columbia University; University of Hawaii System; University of Hawaii Manoa; Vassar College; Utah System of Higher Education; Utah State University; University of California System; University of California Santa Cruz
摘要：The late Paleocene and early Eocene (LPEE) are characterized by long-term (million years, Myr) global warming and by transient, abrupt (kiloyears, kyr) warming events, termed hyperthermals. Although both have been attributed to greenhouse (CO2) forcing, the longer-term trend in climate was likely influenced by additional forcing factors (i.e., tectonics) and the extent to which warming was driven by atmospheric CO2 remains unclear. Here, we use a suite of new and existing observations from pla...
