9期

最新文章

• Ancient ocean coastal deposits imaged on Mars AI翻译
  作者：Li, Jianhui; Liu, Hai; Meng, Xu; Duan, Diwen; Lu, Haijing; Zhang, Jinhai; Zhang, Fengshou; Elsworth, Derek; Cardenas, Benjamin T.; Manga, Michael; Zhou, Bin; Fang, Guangyou
  作者单位：Guangzhou University; Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Tongji University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of California System; University of California Berkeley; Chinese Academy of Sciences; Aerospace Information Research Institute, CAS
  摘要：The northern lowlands of early Mars could have contained a significant quantity of liquid water. However, the ocean hypothesis remains controversial due to the lack of conclusive evidence from the Martian subsurface. We use data from the Zhurong Rover Penetrating Radar on the southern Utopia Planitia to identify subsurface dipping reflectors indicative of an ancient prograding shoreline. The reflectors dip unidirectionally with inclinations in the range 6 degrees to 20 degrees and are imaged t...
• Computational biology predicts metabolic engineering targets for increased production of 103 valuable chemicals in yeast AI翻译
  作者：Domenzain, Ivan; Lu, Yao; Wang, Haoyu; Shi, Junling; Lu, Hongzhong; Nielsen, Jens
  作者单位：Chalmers University of Technology; Chalmers University of Technology; Northwest A&F University - China; Shanghai Jiao Tong University; Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Northwestern Polytechnical University
  摘要：Development of efficient cell factories that can compete with traditional chemical production processes is complex and generally driven by case- specific strategies, based on the product and microbial host of interest. Despite major advancements in the field of metabolic modeling in recent years, prediction of genetic modifications for increased production remains challenging. Here, we present a computational pipeline that leverages the concept of protein limitations in metabolism for predicti...
• A degenerate telomerase RNA directs telomeric DNA synthesis in lepidopteran insects AI翻译
  作者：Chou, Yu - Shu; Logeswaran, Dhenugen; Chow, Chi - Nga; Dunn, Phoebe L.; Podlevsky, Joshua D.; Liu, Tianxiang; Akhter, Khadiza; Chen, Julian J. - L.
  作者单位：Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe; United States Department of Energy (DOE); Sandia National Laboratories
  摘要：Telomerase elongates telomeres to maintain chromosome stability in most eukaryotes. Despite extensive studies across eukaryotic kingdoms, the telomerase holoenzyme in arthropods remains poorly understood. In this study, we purify the telomerase ribonucleoprotein complex from the lepidopteran insect Spodoptera frugiperda (fall army- worm) and identify a copurified 135- nucleotide telomerase RNA (TR) component. This miniature S. frugiperda TR (sfTR), the smallest TR known to date, retains a univ...
• Reply to Smith and Siegel: Most lithium hops in paddlewheel-claimed conductors occur without spatially and temporally correlated anion-group rotations AI翻译
  作者：Jun, Kyujung; Ceder, Gerbrand
  作者单位：University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory
• Innovation in ant larval feeding facilitated queen-worker divergence and social complexity AI翻译
  作者：Matte, Arthur; Leboeuf, Adria C.
  作者单位：University of Cambridge; University of Fribourg
  摘要：Building differences between genetically equivalent units is a fundamental challenge for all multicellular organisms and superorganisms. In ants, reproductive or worker fate is typically determined during the larval stage, through feeding regimes managed by adult caretakers. However, the feeding care provided to larvae varies significantly across ants, as does phenotypic divergence between queen and worker castes. Here, we employed comparative phylogenetic methods and causal inference to inves...
• Revisiting lipid nanoparticle composition and structure: A critical take on simulation approaches AI翻译
  作者：Trollmann, Marius F. W.; Rossetti, Paolo; Boeckmann, Rainer A.
  作者单位：University of Erlangen Nuremberg; University of Erlangen Nuremberg
• Photon-drag photovoltaic effects and quantum geometric nature AI翻译
  作者：Xie, Ying-Min; Nagaosa, Naoto
  作者单位：RIKEN; RIKEN
  摘要：The bulk photovoltaic effect (BPVE) generates a direct current photocurrent under uniform irradiation and is a nonlinear optical effect traditionally studied in noncentrosymmetric materials. The two main origins of BPVE are the shift and injection currents, arising from transitions in electron position and electron velocity during optical excitation, respectively. Recently, it was proposed that photon-drag effects could unlock BPVE in centrosymmetric materials. However, experimental progress r...
• Defects induce phase transition from dynamic to static rippling in graphene AI翻译
  作者：Thiemann, Fabian L.; Scalliet, Camille; Michaelides, Angelos; Avouris, Phaedon
  作者单位：University of Cambridge; Universite Paris Cite; Sorbonne Universite; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); Imperial College London
  摘要：Two-dimensional (2D) materials display nanoscale dynamic ripples that significantly impact their properties. Defects within the crystal lattice are the elementary building blocks to tailor the material's morphology. While some studies have explored the link between defective structures and rippling dynamics in 2D materials, a comprehensive understanding of this relationship has yet to be achieved. Here, we address this using machine learning-driven molecular dynamics simulations. Specifically,...
• High- resolution structures of Myosin- IC reveal a unique actin- binding orientation, ADP release pathway, and power stroke trajectory AI翻译
  作者：Chavali, Sai Shashank; Carman, Peter J.; Shuman, Henry; Ostap, E. Michael; Sindelar, Charles, V
  作者单位：Yale University; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania
  摘要：Myosin- IC (myo1c) is a class- I myosin that supports transport and remodeling of the plasma membrane and membrane- bound vesicles. Like other members of the myosin family, its biochemical kinetics are altered in response to changes in mechanical loads that resist the power stroke. However, myo1c is unique in that the primary force- sensitive kinetic transition is the isomerization that follows ATP binding, not ADP release as in other slow myosins. Myo1c also powers actin gliding along curved ...
• Reply to Trollmann et al.: Perspective on LNP structure and simulation AI翻译
  作者：Garaizar, Adiran; Diaz-Oviedo, David; Zablowsky, Nina; Rissanen, Sami; Koebberling, Johannes; Sun, Jiawei; Steiger, Christoph; Steigemann, Patrick; Mann, Florian A.; Meier, Katharina
  作者单位：Bayer AG; Bayer Healthcare Pharmaceuticals; Bayer AG; Bayer CropScience; Bayer AG; Bayer Healthcare Pharmaceuticals