17期

最新文章

• Ecologically informed solar enables a sustainable energy transition in US croplands AI翻译
  作者：Sturchio, Matthew A.; Gallaher, Adam; Grodsky, Steven M.
  作者单位：Cornell University; Colorado State University System; Colorado State University Fort Collins; Cornell University; United States Department of the Interior; United States Geological Survey
  摘要：United States (US) croplands are ideal recipient environments for solar photovoltaic (PV) energy because they are flat and have a high solar resource. Perceived threats of solar to agriculture have led some stakeholders to suggest that croplands be exclusively used to produce food. However, 12 million hectares of US croplands, an area about the size of New York State, are already dedicated to corn grown for ethanol (i.e., biofuel), an energy product that requires significantly more land than s...
• Trophic convergence of marine vertebrate communities worldwide AI翻译
  作者：Gonzalez-Trujillo, Juan David; Assis, Jorge; Serrao, Ester; Costello, Mark John; Fragkopoulou, Eliza; Mendoza, Manuel; Araujo, Miguel B.
  作者单位：University of Evora; University of Evora; Consejo Superior de Investigaciones Cientificas (CSIC); Universidad Nacional de Colombia; Universidade do Algarve; Nord University; Okinawa Institute of Science & Technology Graduate University
  摘要：Biogeographic regions arise due to constraints on species ranges, fostering lineage divergence as a result. Yet, convergent evolution means that evolutionary distinct lineages can share similar characteristics when subjected to similar environmental conditions. The ecological convergence of distinct regions has been demonstrated in terrestrial communities, but it remains uncertain if marine systems exhibit similar patterns, given the greater ease of dispersal in the ocean. Using information on...
• FlgY, PflA, and PflB form a spoke-ring network in the high- torque flagellar motor of Helicobacter pylori AI翻译
  作者：Tachiyama, Shoichi; Rosinke, Kyle; Khan, Mohammad F.; Zhou, Xiaotian; Xin, Yue; Botting, Jack M.; Yue, Jian; Roujeinikova, Anna; Hoover, Timothy R.; Liu, Jun
  作者单位：Yale University; Yale University; University System of Georgia; University of Georgia; Monash University; Monash University
  摘要：Helicobacter pylori has evolved distinct flagellar motility to colonize the human stomach. Rotation of the H. pylori flagella is driven by one of the largest known bacterial flagellar motors. In addition to the core motor components found in Escherichia coli and Salmonella enterica, the flagellar motor in H. pylori possesses many accessories that enable the bacteria to penetrate the gastric mucus layer. Here, we utilize cryoelectron tomography with molecular genetics and biochemical approaches...
• Abiotic origin of the citric acid cycle intermediates AI翻译
  作者：McAnally, Mason; Bockova, Jana; Turner, Andrew M.; Hara, Nana; Mikhnova, Daria; Meinert, Cornelia; Kaiser, Ralf I.
  作者单位：University of Hawaii System; University of Hawaii Manoa; University of Hawaii System; University of Hawaii Manoa; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite Cote d'Azur
  摘要：The molecular framework for protometabolism-chemical reactions in a prebiotic environment preceding modern metabolism-has remained unknown in evolutionary biology. Mono-, di-, and tricarboxylic acids that comprise contemporary metabolism, such as the Krebs cycle, are of particular prebiotic relevance and are theorized to predate life on Earth. Researchers have struggled to unravel the molecular origins of respiration, with theories pointing toward abiotic origins later co-opted by the earliest...
• PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes AI翻译
  作者：Uchiyama, Lauren F.; Nguyen, Alexander; Qian, Kevin; Cui, Liujuan; Pham, Khoi T.; Xiao, Xu; Gao, Yajing; Shimanaka, Yuta; Tol, Marcus J.; Vergnes, Laurent; Reue, Karen; Tontonoz, Peter
  作者单位：University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles
  摘要：Ketogenesis requires fatty acid flux from intracellular (lipid droplets) and extrahepatic (adipose tissue) lipid stores to hepatocyte mitochondria. However, whether interorganelle contact sites regulate this process is unknown. Recent studies have revealed a role protein, in the control of lipid utilization in adipose tissue. Here, we show that Clstn3b expression is induced in the liver by the nuclear receptor PPAR alpha in settings of high lipid utilization, including fasting and ketogenic di...
• Molecular organization of central cholinergic synapses AI翻译
  作者：Rosenthal, Justin S.; Zhang, Dean; Yin, Jun; Long, Caixia; Yang, George; Li, Yan; Lu, Zhiyuan; Li, Wei-Ping; Yu, Zhiheng; Li, Jiefu; Yuan, Quan
  作者单位：National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS); Howard Hughes Medical Institute
  摘要：Synapses have undergone significant diversification and adaptation, contributing to the complexity of the central nervous system. Understanding their molecular architecture is essential for deciphering the brain's functional evolution. While nicotinic acetylcholine receptors (nAchRs) are widely distributed across metazoan brains, their associated protein networks remain poorly characterized. Using in vivo proximity labeling, we generated proteomic maps of subunit- specific nAchR interactomes i...
• Start your engines: How migratory fibroblasts respond to and remember mechanical stretch AI翻译
  作者：Weihs, Daphne
  作者单位：Technion Israel Institute of Technology; Ghent University; Ghent University Hospital; Hasselt University; Hasselt University
• The tilt illusion arises from an efficient reallocation of neural coding resources at the contextual boundary AI翻译
  作者：Zhang, Ling-Qi; Mao, Jiang; Aguirre, Geoffrey K.; Stocker, Alan A.
  作者单位：University of Pennsylvania; University of Pennsylvania
  摘要：The tilt illusion-a bias in the perceived orientation of a center stimulus induced by an oriented surround-illustrates how context shapes visual perception. Although extensively studied for decades, we still lack a comprehensive account of the illusion that connects its behavioral and neural characteristics. Here, we demonstrate that the tilt illusion originates from dynamic changes in neural coding precision induced by the surround context. We simultaneously obtained psychophysical and functi...
• tRNA selectivity during ribosome-associated quality control regulates the critical sterility-inducing temperature in two-line hybrid rice (vol 122, e2417526122, 2025) AI翻译
  作者：Zhou, Can; Liu, Chunyan; Yan, Bin; Sun, Jing; Li, Shengdong; Li, Ji; Wang, Jia; Huang, Xiahe; Yan, Wei; Yang, Shuying; Fu, Chenjian; Qin, Peng; Fu, Xingxue; Zhao, Xinghui; Wu, Yaxian; Song, Xianwei; Wang, Yingchun; Qian, Wenfeng; Yang, Yuanzhu; Cao, Xiaofeng
• Computational analysis of 100 K choice dilemmas: Decision attributes, trade- off structures, and model- based prediction AI翻译
  作者：Bhatia, Sudeep; van Baal, Simon T.; Wang, Feiyi; Walasek, Lukasz
  作者单位：University of Pennsylvania; University of Leeds; University of Warwick
  摘要：We present a dataset of over 100 K textual descriptions of real- life choice dilemmas, obtained from social media posts and large- scale survey data. Using large language models (LLMs), we extract hundreds of choice attributes at play in these dilemmas and map them onto a common representational space. This representation allows us to quantify the broader themes and specific trade- offs inherent in life choices and analyze how they vary across different contexts. We also present our dilemmas t...