作者:Overbey, Eliah G.; Kim, JangKeun; Tierney, Braden T.; Park, Jiwoon; Houerbi, Nadia; Lucaci, Alexander G.; Medina, Sebastian Garcia; Damle, Namita; Najjar, Deena; Grigorev, Kirill; Afshin, Evan E.; Ryon, Krista A.; Sienkiewicz, Karolina; Patras, Laura; Klotz, Remi; Ortiz, Veronica; MacKay, Matthew; Schweickart, Annalise; Chin, Christopher R.; Sierra, Maria A.; Valenzuela, Matias F.; Dantas, Ezequiel; Nelson, Theodore M.; Cekanaviciute, Egle; Deards, Gabriel; Foox, Jonathan; Narayanan, S. Anand; Schmidt, Caleb M.; Schmidt, Michael A.; Schmidt, Julian C.; Mullane, Sean; Tigchelaar, Seth Stravers; Levitte, Steven; Westover, Craig; Bhattacharya, Chandrima; Lucotti, Serena; Hirschberg, Jeremy Wain; Proszynski, Jacqueline; Burke, Marissa; Kleinman, Ashley S.; Butler, Daniel J.; Loy, Conor; Mzava, Omary; Lenz, Joan; Paul, Doru; Mozsary, Christopher; Sanders, Lauren M.; Taylor, Lynn E.; Patel, Chintan O.; Khan, Sharib A.; Mohamad, Mir Suhail; Byhaqui, Syed Gufran Ahmad; Aslam, Burhan; Gajadhar, Aaron S.; Williamson, Lucy; Tandel, Purvi; Yang, Qiu; Chu, Jessica; Benz, Ryan W.; Siddiqui, Asim; Hornburg, Daniel; Blease, Kelly; Moreno, Juan; Boddicker, Andrew; Zhao, Junhua; Lajoie, Bryan; Scott, Ryan T.; Gilbert, Rachel R.; Polo, San-huei Lai; Altomare, Andrew; Kruglyak, Semyon; Levy, Shawn; Ariyapala, Ishara; Beer, Joanne; Zhang, Bingqing; Hudson, Briana M.; Rininger, Aric; Church, Sarah E.; Beheshti, Afshin; Church, George M.; Smith, Scott M.; Crucian, Brian E.; Zwart, Sara R.; Matei, Irina; Lyden, David C.; Garrett-Bakelman, Francine; Krumsiek, Jan; Chen, Qiuying; Miller, Dawson; Shuga, Joe; Williams, Stephen; Nemec, Corey; Trudel, Guy; Pelchat, Martin; Laneuville, Odette; De Vlaminck, Iwijn; Gross, Steven; Bolton, Kelly L.; Bailey, Susan M.; Granstein, Richard; Furman, David; Melnick, Ari M.; Costes, Sylvain V.; Shirah, Bader; Yu, Min; Menon, Anil S.; Mateus, Jaime; Meydan, Cem; Mason, Christopher E.
作者单位:Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Babes Bolyai University from Cluj; University of Southern California; Buck Institute for Research on Aging; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; Columbia University; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; State University System of Florida; Florida State University; Colorado State University System; Colorado State University Fort Collins; SpaceX; Stanford University; Houston Methodist; Cornell University; Cornell University; Weill Cornell Medicine; Colorado State University System; Colorado State University Fort Collins; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; NanoString Technologies; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard Medical School; National Aeronautics & Space Administration (NASA); NASA Johnson Space Center; University of Texas System; University of Texas Medical Branch Galveston; University of Virginia; University of Virginia; Cornell University; Weill Cornell Medicine; University of Ottawa; Ottawa Hospital Research Institute; University of Ottawa; Ottawa Hospital Research Institute; University of Ottawa; University of Ottawa; University of Ottawa; Washington University (WUSTL); Colorado State University System; Colorado State University Fort Collins; Cornell University; Weill Cornell Medicine; Stanford University; Austral University; Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); King Faisal Specialist Hospital & Research Center; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine
摘要:Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space(1-6). Yet current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools and protocols. Here we present the Space Omics and Medical Atlas (SOMA), an int...
作者:Zalasiewicz, Jan; Thomas, Julia Adeney; Waters, Colin N.; Turner, Simon; Head, Martin J.
作者单位:University of Leicester; University of Notre Dame; University of Leicester; University of London; University College London; Brock University
摘要:Even though geologists have rejected the designation of an Anthropocene epoch, the idea of a major planetary transition in the mid-twentieth century remains useful across physical and social sciences, the humanities and policy.
作者:Li, Huanhuan; Teng, Jinfeng; Hibbs, Ryan E.
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:During development, motor neurons originating in the brainstem and spinal cord form elaborate synapses with skeletal muscle fibres(1). These neurons release acetylcholine (ACh), which binds to nicotinic ACh receptors (AChRs) on the muscle, initiating contraction. Two types of AChR are present in developing muscle cells, and their differential expression serves as a hallmark of neuromuscular synapse maturation(2-4). The structural principles underlying the switch from fetal to adult muscle rece...
作者:Chen, Yuliang; Samanta, Kartik; Shahed, Naafis A.; Zhang, Haojie; Fang, Chi; Ernst, Arthur; Tsymbal, Evgeny Y.; Parkin, Stuart S. P.
作者单位:Max Planck Society; University of Nebraska System; University of Nebraska Lincoln; University of Nebraska System; University of Nebraska Lincoln; Johannes Kepler University Linz
摘要:Antiferromagnetic spintronics(1,2) shows great potential for high-density and ultrafast information devices. Magnetic tunnel junctions (MTJs), a key spintronic memory component that are typically formed from ferromagnetic materials, have seen rapid developments very recently using antiferromagnetic materials(3,4). Here we demonstrate a twisting strategy for constructing all-antiferromagnetic tunnel junctions down to the atomic limit. By twisting two bilayers of CrSBr, a 2D antiferromagnet (AFM...
作者:Wang, Tao; Xu, Ke; Wu, Yuxuan; Shi, Yong; Elbaz, David; Ho, Luis C.; Zhang, Zhi-Yu; Gu, Qiusheng; Wang, Yijun; Shu, Chenggang; Yuan, Feng; Xia, Xiaoyang; Wang, Kai
作者单位:Nanjing University; Nanjing University; Universite Paris Saclay; CEA; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Peking University; Peking University; Shanghai Normal University; Fudan University; Fudan University; Tianjin Normal University
摘要:The nucleus of almost all massive galaxies contains a supermassive black hole (BH)(1). The feedback from the accretion of these BHs is often considered to have crucial roles in establishing the quiescence of massive galaxies(2-14), although some recent studies show that even galaxies hosting the most active BHs do not exhibit a reduction in their molecular gas reservoirs or star formation rates(15-17). Therefore, the influence of BHs on galaxy star formation remains highly debated and lacks di...
作者:Kohtz, Anthony J.; Petrosian, Nikolai; Krukenberg, Viola; Jay, Zackary J.; Pilhofer, Martin; Hatzenpichler, Roland
作者单位:Montana State University System; Montana State University Bozeman; Montana State University System; Montana State University Bozeman; Swiss Federal Institutes of Technology Domain; ETH Zurich; Montana State University System; Montana State University Bozeman
摘要:Methane is the second most abundant climate-active gas, and understanding its sources and sinks is an important endeavour in microbiology, biogeochemistry, and climate sciences(1,2). For decades, it was thought that methanogenesis, the ability to conserve energy coupled to methane production, was taxonomically restricted to a metabolically specialized group of archaea, the Euryarchaeota(1). The discovery of marker genes for anaerobic alkane cycling in metagenome-assembled genomes obtained from...