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作者:Zhang, Tao; Li, Jiabiao; Niu, Xiongwei; Ding, Weiwei; Fang, Yinxia; Lin, Jian; Wang, Yejian; Zha, Caicai; Tan, Pingchuan; Kong, Fansheng; Chen, Jie; Wei, Xiaodong; Lu, Jianggu; Dyment, Jerome; Morgan, Jason P.
作者单位:Ministry of Natural Resources of the People's Republic of China; Second Institute of Oceanography, Ministry of Natural Resources; Southern University of Science & Technology; Chinese Academy of Sciences; South China Sea Institute of Oceanology, CAS; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite
摘要:Crustal accretion at mid-ocean ridges governs the creation and evolution of the oceanic lithosphere. Generally accepted models(1-4) of passive mantle upwelling and melting predict notably decreased crustal thickness at a spreading rate of less than 20mmyear(-1). We conducted the first, to our knowledge, high-resolution ocean-bottom seismometer (OBS) experiment at the Gakkel Ridge in the Arctic Ocean and imaged the crustal structure of the slowest-spreading ridge on the Earth. Unexpectedly, we ...
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作者:Huang, Yixin; Wang, Tongyun; Zhong, Lijie; Zhang, Wenxin; Zhang, Yu; Yu, Xiulian; Yuan, Shuofeng; Ni, Tao
作者单位:University of Hong Kong; University of Hong Kong; Hong Kong Polytechnic University; University of Hong Kong
摘要:Coronaviruses remodel the intracellular host membranes during replication, forming double-membrane vesicles (DMVs) to accommodate viral RNA synthesis and modifications(1,2). SARS-CoV-2 non-structural protein 3 (nsp3) and nsp4 are the minimal viral components required to induce DMV formation and to form a double-membrane-spanning pore, essential for the transport of newly synthesized viral RNAs3-5. The mechanism of DMV pore complex formation remains unknown. Here we describe the molecular archi...
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作者:McCarthy, Margaret M.
作者单位:University System of Maryland; University of Maryland Baltimore
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作者:[Anonymous]
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作者:Blodgett, Su Lin; Talat, Zeerak
作者单位:Mohamed bin Zayed University of Artificial Intelligence MBZUAI
摘要:Large language models (LLMs) are becoming less overtly racist, but respond negatively to text in African American English. Such 'covert' racism could harm speakers of this dialect when LLMs are used for decision-making.
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作者:Kudiabor, Helena; McFall, John
作者单位:European Space Agency
摘要:Nature speaks to the world's first disabled astronaut about his hopes for the future of space exploration.
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作者:Rathje, Steve
作者单位:New York University
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作者:[Anonymous]
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作者:Recaldin, Timothy; Steinacher, Linda; Gjeta, Bruno; Harter, Marius F.; Adam, Lukas; Kromer, Kristina; Mendes, Marisa Pimentel; Bellavista, Marina; Nikolaev, Mikhail; Lazzaroni, Giacomo; Krese, Rok; Kilik, Umut; Popovic, Doris; Stoll, Bilgenaz; Gerard, Regine; Bscheider, Michael; Bickle, Marc; Cabon, Lauriane; Camp, J. Gray; Gjorevski, Nikolche
作者单位:Roche Holding; Hannover Medical School; University of Basel; Universite Paris Saclay
摘要:The intimate relationship between the epithelium and immune system is crucial for maintaining tissue homeostasis, with perturbations therein linked to autoimmune disease and cancer1-3. Whereas stem cell-derived organoids are powerful models of epithelial function4, they lack tissue-resident immune cells that are essential for capturing organ-level processes. We describe human intestinal immuno-organoids (IIOs), formed through self-organization of epithelial organoids and autologous tissue-resi...
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作者:Lavine, Kory