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• The surprising culprit for the loss of huge swathes of tropical forest AI翻译
  作者：[Anonymous]
• CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors ( vol 635, 462, 2024) AI翻译
  作者：Skoulidis, Ferdinandos; Araujo, Haniel A.; Do, Minh Truong; Qian, Yu; Sun, Xin; Cobo, Ana Galan; Le, John T.; Montesion, Meagan; Palmer, Rachael; Jahchan, Nadine; Juan, Joseph M.; Min, Chengyin; Yu, Yi; Pan, Xuewen; Arbour, Kathryn C.; Vokes, Natalie; Schmidt, Stephanie T.; Molkentine, David; Owen, Dwight H.; Memmott, Regan; Patil, Pradnya D.; Marmarelis, Melina E.; Awad, Mark M.; Murray, Joseph C.; Hellyer, Jessica A.; Gainor, Justin F.; Dimou, Anastasios; Bestvina, Christine M.; Shu, Catherine A.; Riess, Jonathan W.; Blakely, Collin M.; Pecot, Chad V.; Mezquita, Laura; Tabbo, Fabrizio; Scheffler, Matthias; Digumarthy, Subba; Mooradian, Meghan J.; Sacher, Adrian G.; Lau, Sally C. M.; Saltos, Andreas N.; Rotow, Julia; Johnson, Rocio Perez; Liu, Corinne; Stewart, Tyler; Goldberg, Sarah B.; Killam, Jonathan; Walther, Zenta; Schalper, Kurt; Davies, Kurtis D.; Woodcock, Mark G.; Anagnostou, Valsamo; Marrone, Kristen A.; Forde, Patrick M.; Ricciuti, Biagio; Venkatraman, Deepti; Van Allen, Eliezer M.; Cummings, Amy L.; Goldman, Jonathan W.; Shaish, Hiram; Kier, Melanie; Katz, Sharyn; Aggarwal, Charu; Ni, Ying; Azok, Joseph T.; Segal, Jeremy; Ritterhouse, Lauren; Neal, Joel W.; Lacroix, Ludovic; Elamin, Yasir Y.; Negrao, Marcelo V.; Le, Xiuning; Lam, Vincent K.; Lewis, Whitney E.; Kemp, Haley N.; Carter, Brett; Roth, Jack A.; Swisher, Stephen; Lee, Richard; Zhou, Teng; Poteete, Alissa; Kong, Yifan; Takehara, Tomohiro; Paula, Alvaro Guimaraes; Cuentas, Edwin R. Parra; Behrens, Carmen; Wistuba, Ignacio I.; Zhang, Jianjun; Blumenschein, George R.; Gay, Carl; Byers, Lauren A.; Gibbons, Don L.; Tsao, Anne; Lee, J. Jack; Bivona, Trever G.; Camidge, D. Ross; Gray, Jhannelle E.; Leighl, Natasha B.; Levy, Benjamin; Brahmer, Julie R.; Garassino, Marina C.; Gandara, David R.; Garon, Edward B.; Rizvi, Naiyer A.; Scagliotti, Giorgio Vittorio; Wolf, Juergen; Planchard, David; Besse, Benjamin; Herbst, Roy S.; Wakelee, Heather A.; Pennell, Nathan A.; Shaw, Alice T.; Jaenne, Pasi A.; Carbone, David P.; Hellmann, Matthew D.; Rudin, Charles M.; Albacker, Lee; Mann, Helen; Zhu, Zhou; Lai, Zhongwu; Stewart, Ross; Peters, Solange; Johnson, Melissa L.; Wong, Kwok K.; Huang, Alan; Winslow, Monte M.; Rosen, Michael J.; Winters, Ian P.; Papadimitrakopoulou, Vassiliki A.; Cascone, Tina; Jewsbury, Philip; Heymach, John V.
• Meet the 'woolly mouse': why scientists doubt it's a big step towards recreating mammoths AI翻译
  作者：Callaway, Ewen
• Peptides from abnormal RNA processing in cancer offer an immunotherapy target AI翻译
  作者：Charest, Al
  作者单位：Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center
• Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy AI翻译
  作者：Falcucci, Lara; Dooley, Christopher M.; Adamoski, Douglas; Juan, Thomas; Martinez, Justin; Georgieva, Angelina M.; Mamchaoui, Kamel; Cirzi, Cansu; Stainier, Didier Y. R.
  作者单位：Max Planck Society; German Centre for Cardiovascular Research; Max Planck Society; Institut National de la Sante et de la Recherche Medicale (Inserm); Sorbonne Universite; Uppsala University
  摘要：Duchenne muscular dystrophy (DMD) is a muscle-degenerating disease caused by mutations in the DMD gene, which encodes the dystrophin protein1,2. Utrophin (UTRN), the genetic and functional paralogue of DMD, is upregulated in some DMD patients3, 4-5. To further investigate this UTRN upregulation, we first developed an inducible messenger RNA (mRNA) degradation system for DMD by introducing a premature termination codon (PTC) in one of its alternatively spliced exons. Inclusion of the PTC-contai...
• Weather anomalies cannot explain insect decline AI翻译
  作者：Hallmann, Caspar A.; Jongejans, Eelke; Hoerren, Thomas; Sorg, Martin; Siepel, Henk; Muehlethaler, Roland; Lehmann, Gerlind U. C.; de Kroon, Hans
  作者单位：Radboud University Nijmegen; Royal Netherlands Academy of Arts & Sciences; Netherlands Institute of Ecology (NIOO-KNAW); University of Duisburg Essen; Humboldt University of Berlin
• Community estimate of global glacier mass changes from 2000 to 2023 AI翻译
  作者：Zemp, Michael; Jakob, Livia; Dussaillant, Ines; Nussbaumer, Samuel U.; Gourmelen, Noel; Dubber, Sophie; Geruo, A.; Abdullahi, Sahra; Andreassen, Liss Marie; Berthier, Etienne; Bhattacharya, Atanu; Blazquez, Alejandro; Boehm Vock, Laura F.; Bolch, Tobias; Box, Jason; Braun, Matthias H.; Brun, Fanny; Cicero, Eric; Colgan, William; Eckert, Nicolas; Farinotti, Daniel; Florentine, Caitlyn; Floricioiu, Dana; Gardner, Alex; Harig, Christopher; Hassan, Javed; Hugonnet, Romain; Huss, Matthias; Johannesson, Tomas; Liang, Chia-Chun Angela; Ke, Chang-Qing; Khan, Shfaqat Abbas; King, Owen; Kneib, Marin; Krieger, Lukas; Maussion, Fabien; Mattea, Enrico; Mcnabb, Robert; Menounos, Brian; Miles, Evan; Moholdt, Geir; Nilsson, Johan; Palsson, Finnur; Pfeffer, Julia; Piermattei, Livia; Plummer, Stephen; Richter, Andreas; Sasgen, Ingo; Schuster, Lilian; Seehaus, Thorsten; Shen, Xiaoyi; Sommer, Christian; Sutterley, Tyler; Treichler, Desiree; Velicogna, Isabella; Wouters, Bert; Zekollari, Harry; Zheng, Whyjay
  作者单位：University of Zurich; University of Edinburgh; University of California System; University of California Irvine; Helmholtz Association; German Aerospace Centre (DLR); Norwegian Water Resources & Energy Directorate; Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Saint Olaf College; Graz University of Technology; Geological Survey Of Denmark & Greenland; University of Erlangen Nuremberg; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Centre National de la Recherche Scientifique (CNRS); Institut de Recherche pour le Developpement (IRD); Institut National Polytechnique de Grenoble; University of Arizona; York University - Canada; Centre National de la Recherche Scientifique (CNRS); Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Institut de Recherche pour le Developpement (IRD); Institut National Polytechnique de Grenoble; INRAE; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Centre National de la Recherche Scientifique (CNRS); Inria; Institut National Polytechnique de Grenoble; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; United States Department of the Interior; United States Geological Survey; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); California Institute of Technology; Technical University of Denmark; University of Washington; University of Washington Seattle; University of Fribourg; Nanjing University; Ministry of Natural Resources of the People's Republic of China; Newcastle University - UK; University of Innsbruck; University of Bristol; Natural Resources Canada; Lands & Minerals Sector - Natural Resources Canada; Geological Survey of Canada; Hakai Institute; University of Northern British Columbia; Norwegian Polar Institute; University of Iceland; University of Oslo; European Space Agency; European Space Research Institute; National University of La Plata; Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; University of Augsburg; Hohai University; University of Washington; University of Washington Seattle; Delft University of Technology; Vrije Universiteit Brussel; National Central University
  摘要：Glaciers are indicators of ongoing anthropogenic climate change1. Their melting leads to increased local geohazards2, and impacts marine3 and terrestrial4,5 ecosystems, regional freshwater resources6, and both global water and energy cycles7,8. Together with the Greenland and Antarctic ice sheets, glaciers are essential drivers of present9,10 and future11, 12-13 sea-level rise. Previous assessments of global glacier mass changes have been hampered by spatial and temporal limitations and the he...
• COP30 must deliver binding mechanisms to address climate change, not empty promises AI翻译
  作者：Fernandes, Stephannie; Ranjan, Pranay
  作者单位：State University System of Florida; Florida International University; Northern Arizona University
• Public-health experts should be more political, not less AI翻译
  作者：Reinhart, Eric
• Magnetically and optically active edges in phosphorene nanoribbons AI翻译
  作者：Ashoka, Arjun; Clancy, Adam J.; Panjwani, Naitik A.; Cronin, Adam; Picco, Loren; Aw, Eva S. Y.; Popiel, Nicholas J. M.; Eaton, Alexander G.; Parton, Thomas G.; Shutt, Rebecca R. C.; Feldmann, Sascha; Carey, Remington; Macdonald, Thomas J.; Liu, Cheng; Severijnen, Marion E.; Kleuskens, Sandra; Muscarella, Loreta A.; Fischer, Felix R.; Barbosa de Aguiar, Hilton; Friend, Richard H.; Behrends, Jan; Christianen, Peter C. M.; Howard, Christopher A.; Pandya, Raj
  作者单位：University of Cambridge; University of London; University College London; University of California System; University of California Berkeley; University of Bristol; University of London; University College London; University of Cambridge; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Imperial College London; Imperial College London; University of London; University College London; Radboud University Nijmegen; AMOLF; Vrije Universiteit Amsterdam; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Universite PSL; College de France; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; University of Warwick
  摘要：Nanoribbons, nanometre-wide strips of a two-dimensional material, are a unique system in condensed matter. They combine the exotic electronic structures of low-dimensional materials with an enhanced number of exposed edges, where phenomena including ultralong spin coherence times1,2, quantum confinement3 and topologically protected states4,5 can emerge. An exciting prospect for this material concept is the potential for both a tunable semiconducting electronic structure and magnetism along the...