8075期

最新文章

• DeepMind and OpenAI models solve maths problems at level of top students AI翻译
  作者：Castelvecchi, Davide
  摘要：For the first time, large language models performed on a par with gold medallists in global maths contests.
• Overcome threats to renewable energy through skilful statecraft AI翻译
  作者：Chandrashekeran, Sangeetha; Fish, Adam; Thurbon, Elizabeth; Sovacool, Benjamin K.
  作者单位：University of Melbourne; University of New South Wales Sydney; University of Sussex
• Magnon spectroscopy in the electron microscope AI翻译
  作者：Kepaptsoglou, Demie; Castellanos-Reyes, Jose Angel; Kerrigan, Adam; Alves do Nascimento, Julio; Zeiger, Paul M.; El Hajraoui, Khalil; Idrobo, Juan Carlos; Mendis, Budhika G.; Bergman, Anders; Lazarov, Vlado K.; Rusz, Jan; Ramasse, Quentin M.
  作者单位：University of York - UK; University of York - UK; Uppsala University; University of Washington; University of Washington Seattle; United States Department of Energy (DOE); Pacific Northwest National Laboratory; Durham University; University of Leeds; University of Leeds
  摘要：The miniaturization of transistors is approaching its limits owing to challenges in heat management and information transfer speed1. To overcome these obstacles, emerging technologies such as spintronics2 are being developed, which make use of the electron's spin as well as its charge. Local phenomena at interfaces or structural defects will greatly influence the efficiency of spin-based devices, making the ability to study spin-wave propagation at the nanoscale and atomic scale a key challeng...
• Neuronal transfer of mitochondria to tumour cells promotes cancer spread AI翻译
  作者：Singh, Anand K.; Pan, Yuan
  作者单位：University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center
• Major expansion in the human niche preceded out of Africa dispersal AI翻译
  作者：Hallett, Emily Y.; Leonardi, Michela; Cerasoni, Jacopo Niccolo; Will, Manuel; Beyer, Robert; Krapp, Mario; Kandel, Andrew W.; Manica, Andrea; Scerri, Eleanor M. L.
  作者单位：Loyola University Chicago; Max Planck Society; University of Cambridge; Natural History Museum London; Loyola University Chicago; Eberhard Karls University of Tubingen; University of Johannesburg; Eberhard Karls University of Tubingen; University of Malta; University of Cologne
  摘要：All contemporary Eurasians trace most of their ancestry to a small population that dispersed out of Africa about 50,000 years ago (ka)1, 2, 3, 4, 5, 6, 7, 8-9. By contrast, fossil evidence attests to earlier migrations out of Africa10, 11, 12, 13, 14-15. These lines of evidence can only be reconciled if early dispersals made little to no genetic contribution to the later, major wave. A key question therefore concerns what factors facilitated the successful later dispersal that led to long-term...
• Don't train medical AI on patients' data without their knowledge AI翻译
  作者：Banerjee, Toral; Lin, Rongyu; Shi, Mengyuan
  作者单位：Clark University; Emory University
• R9AP is a common receptor for EBV infection in epithelial cells and B cells AI翻译
  作者：Li, Yan; Zhang, Hua; Sun, Cong; Dong, Xiao-Dong; Xie, Chu; Liu, Yuan-Tao; Lin, Ruo-Bin; Kong, Xiang-Wei; Hu, Zhu-Long; Ma, Xiao-Yan; Dai, Dan-Ling; Zhu, Qian-Ying; Li, Yu-Chun; Li, Ying; Liu, Shang-Xin; Yuan, Li; Zhou, Peng-Hui; Gao, Song; Tang, Ya-Ping; Yang, Jin-Ying; Han, Ping; McGuire, Andrew T.; Zhao, Bo; Bei, Jin-Xin; Robertson, Erle; Zeng, Yi-Xin; Zhong, Qian; Zeng, Mu-Sheng
  作者单位：State Key Lab Oncology South China; Sun Yat Sen University; Sun Yat Sen University; Sun Yat Sen University; Guangzhou Medical University; Sun Yat Sen University; Fred Hutchinson Cancer Center; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; University of Pennsylvania; Sun Yat Sen University
  摘要：Epstein-Barr virus (EBV) persistently infects more than 90% of the human population, causing infectious mononucleosis1, susceptibility to autoimmune diseases2 and multiple malignancies of epithelial or B cell-origin3. EBV infects epithelial cells and B cells through interaction between viral glycoproteins and different host receptors4, but it has remained unknown whether a common receptor mediates infection of its two major host cell targets. Here, we establish R9AP as a crucial EBV receptor f...
• Mystery food in Neanderthal diet might be maggots AI翻译
  作者：Ahart, Jenna
• A coordinated cellular network regulates tolerance to food AI翻译
  作者：Rudnitsky, Anna; Oh, Hanna; Margolin, Maya; Dassa, Bareket; Shteinberg, Inbar; Stoler-Barak, Liat; Shulman, Ziv; Kedmi, Ranit
  作者单位：Weizmann Institute of Science; Weizmann Institute of Science
  摘要：To absorb nutrients and support commensal microorganisms, the host induces tolerogenic immune responses through peripheral regulatory T (pTreg) cells1,2. Previous studies identified conventional type 1 dendritic cells (cDC1s) as initiators of dietary pTreg cells3. However, here we report that food-specific pTreg cells are induced exclusively by the recently identified ROR gamma t antigen-presenting cells4, 5, 6, 7-8 and not by conventional dendritic cells. Instead, our data suggest that pTreg ...
• A molecular cell atlas of mouse lemur, an emerging model primate AI翻译
  作者：Ezran, Camille; Liu, Shixuan; Chang, Stephen; Ming, Jingsi; Botvinnik, Olga; Penland, Lolita; Tarashansky, Alexander; de Morree, Antoine; Travaglini, Kyle J.; Zhao, Jia; Wang, Gefei; Hasegawa, Kazuteru; Sin, Hosu; Sit, Rene; Okamoto, Jennifer; Sinha, Rahul; Zhang, Yue; Karanewsky, Caitlin J.; Pendleton, Jozeph L.; Morri, Maurizio; Perret, Martine; Aujard, Fabienne; Stryer, Lubert; Artandi, Steven; Fuller, Margaret T.; Weissman, Irving L.; Rando, Thomas A.; Ferrell Jr, James E.; Wang, Bo; De Vlaminck, Iwijn; Yang, Can; Casey, Kerriann M.; Albertelli, Megan A.; Pisco, Angela Oliveira; Karkanias, Jim; Neff, Norma; Wu, Angela Ruohao; Quake, Stephen R.; Krasnow, Mark A.
  作者单位：Stanford University; Howard Hughes Medical Institute; Stanford University; Stanford University; Stanford University; East China Normal University; East China Normal University; Chan Zuckerberg Initiative (CZI); Stanford University; Stanford University; Aarhus University; Hong Kong University of Science & Technology; Stanford University; Stanford Cancer Institute; Stanford University; Stanford University; Stanford University; Stanford University; Museum National d'Histoire Naturelle (MNHN); Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Ecology & Environment (INEE); Stanford University; Stanford University; Cornell University; Stanford University; Hong Kong University of Science & Technology; Hong Kong University of Science & Technology; Hong Kong University of Science & Technology; Stanford University
  摘要：Mouse lemurs are the smallest and fastest reproducing primates, as well as one of the most abundant, and they are emerging as a model organism for primate biology, behaviour, health and conservation. Although much has been learnt about their ecology and phylogeny in Madagascar and their physiology, little is known about their cellular and molecular biology. Here we used droplet-based and plate-based single-cell RNA sequencing to create Tabula Microcebus, a transcriptomic atlas of 226,000 cells...