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作者:Wairagkar, Maitreyee; Card, Nicholas S.; Singer-Clark, Tyler; Hou, Xianda; Iacobacci, Carrina; Miller, Lee M.; Hochberg, Leigh R.; Brandman, David M.; Stavisky, Sergey D.
作者单位:University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis; Brown University; Brown University; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School
摘要:Brain-computer interfaces (BCIs) have the potential to restore communication for people who have lost the ability to speak owing to a neurological disease or injury. BCIs have been used to translate the neural correlates of attempted speech into text1, 2-3. However, text communication fails to capture the nuances of human speech, such as prosody and immediately hearing one's own voice. Here we demonstrate a brain-to-voice neuroprosthesis that instantaneously synthesizes voice with closed-loop ...
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作者:Park, Jong Yoon; Yoon, Young Dae; Hwang, Yong-Seok
作者单位:Seoul National University (SNU); Asia Pacific Center for Theoretical Physics; Pohang University of Science & Technology (POSTECH)
摘要:Cross-scale coupling from magnetohydrodynamics (MHD) to non-MHD scales is important in interpreting observations of explosive events in nature, such as solar flares and geomagnetic storms1,2. Experiments and observations also link it to the emergence of energetic particles and X-rays3. However, how this multi-scale physics affects the abrupt onset of reconnection remains unknown. Here we report observations from laboratory experiments involving two flux ropes with electron beams that induce ma...
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作者:Alighanbari, S.; Schenkel, M. R.; Korobov, V. I.; Schiller, S.
作者单位:Heinrich Heine University Dusseldorf; Joint Institute for Nuclear Research - Russia
摘要:The molecular hydrogen ions (MHI) are three-body systems suitable for advancing our knowledge in several domains: fundamental constants, tests of quantum physics, search for new interparticle forces, tests of the weak equivalence principle(1) and, once the anti-molecule (p) over bar(p) over bare(+) becomes available, new tests of charge-parity-time-reversal invariance and local position invariance(1-3). To achieve these goals, high-accuracy laser spectroscopy of several isotopologues, in parti...
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作者:Sharifi, Ayyoob
作者单位:Hiroshima University
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作者:Ledvina, Hannah E.; Sayegh, Ryan; Carale, Ricardo O.; Burroughs, A. Maxwell; Macklin, Alexa R.; Azadeh, Ashley L.; Najera, Layla D. Borja; Aravind, L.; Whiteley, Aaron T.
作者单位:University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder; National Institutes of Health (NIH) - USA; Division of Intramural Research (DIR); NIH National Library of Medicine (NLM)
摘要:Bdellovibrio bacteriovorus is a predatory bacterium that non-selectively preys on Gram-negative bacteria by invading the prey-cell periplasm, leaching host nutrients and ultimately lysing the infected cell to exit and find a new host1,2. The predatory life cycle of B. bacteriovorus is, in many ways, comparable to a bacteriophage. However, unlike phage defence, defence against B. bacteriovorus has not been widely investigated. Here we screened a collection of diverse Escherichia coli strains fo...
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作者:Brooks, Michael
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作者:Poterucha, Timothy J.; Jing, Linyuan; Ricart, Ramon Pimentel; Adjei-Mosi, Michael; Finer, Joshua; Hartzel, Dustin; Kelsey, Christopher; Long, Aaron; Rocha, Daniel; Ruhl, Jeffrey A.; vanMaanen, David; Probst, Marc A.; Daniels, Brock; Joshi, Shalmali D.; Tastet, Olivier; Corbin, Denis; Avram, Robert; Barrios, Joshua P.; Tison, Geoffrey H.; Chiu, I-Min; Ouyang, David; Volodarskiy, Alexander; Castillo, Michelle; Oliver, Francisco A. Roedan; Malta, Paloma P.; Ye, Siqin; Rosner, Gregg F.; Dizon, Jose M.; Ali, Shah R.; Liu, Qi; Bradley, Corey K.; Vaishnava, Prashant; Waksmonski, Carol A.; DeFilippis, Ersilia M.; Agarwal, Vratika; Lebehn, Mark; Kampaktsis, Polydoros N.; Shames, Sofia; Beecy, Ashley N.; Kumaraiah, Deepa; Homma, Shunichi; Schwartz, Allan; Hahn, Rebecca T.; Leon, Martin; Einstein, Andrew J.; Maurer, Mathew S.; Hartman, Heidi S.; Hughes, John Weston; Haggerty, Christopher M.; Elias, Pierre
作者单位:Columbia University; NewYork-Presbyterian Hospital; NewYork-Presbyterian Hospital; Columbia University; Columbia University; Columbia University; NewYork-Presbyterian Hospital; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Universite de Montreal; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Cedars Sinai Medical Center; Chang Gung Memorial Hospital; Cornell University; Weill Cornell Medicine; Cardiovascular Research Foundation (CRF); Columbia University; NewYork-Presbyterian Hospital
摘要:Early detection of structural heart disease is critical to improving outcomes, but widespread screening remains limited by the cost and accessibility of imaging tools such as echocardiography1,2. Recent advances in machine learning applied to heart rhythm recordings have shown promise in identifying disease3,4, although previous work has been limited by development in narrow populations or targeting only select heart conditions5. Here we introduce a deep learning model, EchoNext, trained on mo...
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作者:Sukalskaia, Anastasiia; Karner, Andreas; Pugnetti, Anna; Weber, Florian; Plochberger, Birgit; Dutzler, Raimund
作者单位:University of Zurich
摘要:The Tweety homologues (TTYHs) constitute a family of eukaryotic membrane proteins that, on the basis of structural features, were recently proposed to contribute to lipid transfer between soluble carriers and cellular membranes1. However, in the absence of supporting data, this function was hypothetical. Here through pull-down of endogenous proteins, we identify APOE as the interaction partner of human TTYH2. Subcellular fractionation and immunocytochemistry assays showed that both proteins co...
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作者:Kavanagh, Katie
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作者:Liu, Lu; Xiong, Langlang; Wang, Chongwu; Bai, Yihua; Ma, Weiliang; Wang, Yupeng; Li, Peining; Li, Guogang; Wang, Qi Jie; Garcia-Vidal, Francisco J.; Dai, Zhigao; Hu, Guangwei
作者单位:China University of Geosciences; Nanyang Technological University; University of Electronic Science & Technology of China; Huazhong University of Science & Technology; Huazhong University of Science & Technology; China University of Geosciences; Autonomous University of Madrid; Autonomous University of Madrid; China University of Geosciences; Nanyang Technological University
摘要:Hybridized matter-photon excitations in hyperbolic crystals-anisotropic materials characterized by permittivity tensor components with opposite sign-have attracted substantial attention owing to their strong light-matter interactions in the form of hyperbolic polaritons1, 2-3. However, these phenomena have been restricted to hyperbolic crystals, whose optical responses are confined to fixed spectral regions and lack tunability, thereby limiting their broader applicability4,5. Here we demonstra...