8082期

最新文章

• Combat the human-made causes of Spain's wildfires AI翻译
  作者：Aviles, Jesus Miguel
  作者单位：Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Estacion Experimental de Zonas Aridas (EEZA)
• The mini placentas and ovaries revealing the basics of women's health AI翻译
  作者：Willyard, Cassandra
• Electrostatic-repulsion-based transfer of van der Waals materials AI翻译
  作者：Zheng, Xudong; Wang, Jiangtao; Jiang, Jianfeng; Zhang, Tianyi; Zhu, Jiadi; Dang, Tong; Wu, Peng; Lu, Ang-Yu; Chen, Ding-Rui; Yang, Tilo H.; Zhang, Xinyuan; Zhang, Kenan; Ma, Kyung Yeol; Wang, Zhien; Yao, Aijia; Liu, Haomin; Wan, Yi; Hsieh, Ya-Ping; Bulovic, Vladimir; Palacios, Tomas; Kong, Jing
  作者单位：Massachusetts Institute of Technology (MIT); Academia Sinica - Taiwan; Massachusetts Institute of Technology (MIT); National University of Singapore
  摘要：Van der Waals (vdW) materials offer unique opportunities for 3D integration1,2 of planar circuits towards higher-density transistors and energy-efficient computation3, 4, 5, 6-7. Owing to the high thermal budget and special substrate requirement for the synthesis of high-quality vdW materials8, 9-10, an advanced transfer technique is required that can simultaneously meet a broad range of industrial requirements, including high intactness, cleanliness and speed, large scale, low cost and versat...
• Multiple oestradiol functions inhibit ferroptosis and acute kidney injury AI翻译
  作者：Tonnus, Wulf; Maremonti, Francesca; Gavali, Shubhangi; Schlecht, Marlena Nastassja; Gembardt, Florian; Belavgeni, Alexia; Leinung, Nadja; Flade, Karolin; Bethe, Natalie; Traikov, Sofia; Haag, Anne; Schilling, Danny; Penkov, Sider; Mallais, Melodie; Gaillet, Christine; Meyer, Claudia; Katebi, Melika; Ray, Anushka; Gerhardt, Louisa M. S.; Brucker, Anne; Becker, Jorunn Naila; Tmava, Mirela; Schlicker, Lisa; Schulze, Almut; Himmerkus, Nina; Shevchenko, Andrej; Peitzsch, Mirko; Barayeu, Uladzimir; Nasi, Sonia; Putz, Juliane; Korach, Kenneth S.; Neugarten, Joel; Golestaneh, Ladan; Hugo, Christian; Becker, Jan Ulrich; Weinberg, Joel M.; Lorenz, Svenja; Proneth, Bettina; Conrad, Marcus; Wolf, Eckhard; Plietker, Bernd; Rodriguez, Raphael; Pratt, Derek A.; Dick, Tobias P.; Fedorova, Maria; Bornstein, Stefan R.; Linkermann, Andreas
  作者单位：Technische Universitat Dresden; Carl Gustav Carus University Hospital; Ruprecht Karls University Heidelberg; Technische Universitat Dresden; Carl Gustav Carus University Hospital; Max Planck Society; Technische Universitat Dresden; Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; Technische Universitat Dresden; University of Ottawa; UNICANCER; Universite PSL; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Institut Curie; Helmholtz Association; German Cancer Research Center (DKFZ); University of Kiel; Max Planck Society; University of Lausanne; Centre Hospitalier Universitaire Vaudois (CHUV); Technische Universitat Dresden; Carl Gustav Carus University Hospital; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); Yeshiva University; Montefiore Medical Center; University of Cologne; University of Michigan System; University of Michigan; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; University of Munich; University of Munich; German Center for Diabetes Research (DZD); Technische Universitat Dresden; Carl Gustav Carus University Hospital; University of London; King's College London; Technische Universitat Dresden; Helmholtz Association; Technische Universitat Dresden; Helmholtz-Center Munich - German Research Center for Environmental Health; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine
  摘要：Acute tubular necrosis mediates acute kidney injury (AKI) and nephron loss1, the hallmark of end-stage renal disease2, 3-4. For decades, it has been known that female kidneys are less sensitive to AKI5,6. Acute tubular necrosis involves dynamic cell death propagation by ferroptosis along the tubular compartment7,8. Here we demonstrate abrogated ferroptotic cell death propagation in female kidney tubules. 17 beta-oestradiol establishes an anti-ferroptotic state through non-genomic and genomic m...
• 'Revolutionary' AI tools rescue old weather data: Transcribing centuries-old handwritten records could help to improve climate models AI翻译
  作者：Castelvecchi, Davide
• Soft robot steers itself down the human airway AI翻译
  作者：[Anonymous]
• NASP modulates histone turnover to drive PARP inhibitor resistance AI翻译
  作者：Moser, Sarah C.; Khalizieva, Anna; Roehsner, Josef; Pottendorfer, Elisabeth; Kaptein, Milo L.; Ricci, Giulia; Bhardwaj, Vivek; Bleijerveld, Onno B.; Hoekman, Liesbeth; van der Heijden, Ingrid; di Sanzo, Simone; Fish, Alexander; Chikunova, Aleksandra; Haarhuis, Judith H. I.; Oldenkamp, Roel; Robbez-Masson, Luisa; Sprengers, Justin; Vis, Daniel J.; Wessels, Lodewyk F. A.; van de Ven, Marieke; Pettitt, Stephen J.; Tutt, Andrew N. J.; Lord, Christopher J.; Rowland, Benjamin D.; Voelker-Albert, Moritz; Mattiroli, Francesca; Brummelkamp, Thijn R.; Mazouzi, Abdelghani; Jonkers, Jos
  作者单位：Netherlands Cancer Institute; Leiden University - Excl LUMC; Leiden University; Royal Netherlands Academy of Arts & Sciences; Hubrecht Institute (KNAW); Utrecht University; Utrecht University Medical Center; Utrecht University; Netherlands Cancer Institute; Netherlands Cancer Institute; Netherlands Cancer Institute; University of London; Royal Marsden NHS Foundation Trust; Institute of Cancer Research - UK; Netherlands Cancer Institute; Netherlands Cancer Institute; Guy's & St Thomas' NHS Foundation Trust; University of London; King's College London
  摘要：The poly(ADP-ribose) polymerase inhibitor (PARPi) class of drugs represents a remarkable advance in the treatment of patients with homologous recombination-deficient tumours, but resistance remains a challenge1, 2, 3, 4-5. Although most research has focused on the downstream consequences of PARPi exposure to tackle resistance, the immediate effect of PARP inhibition on the chromatin environment and its contribution to PARPi toxicity remains elusive. Here we show that PARP inhibition induces hi...
• The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution AI翻译
  作者：Sebe-Pedros, Arnau; Tanay, Amos; Lawniczak, Mara K. N.; Arendt, Detlev; Aerts, Stein; Archibald, John; Arnone, Maria Ina; Blaxter, Mark; Cleves, Phillip; Coelho, Susana M.; Dias, Mafalda; Dunn, Casey; Elek, Anamaria; Frazer, Jonathan; Gabaldon, Toni; Gillis, Jesse; Grau-Bove, Xavier; Guigo, Roderic; Hobert, Oliver; Huerta-Cepas, Jaime; Irimia, Manuel; Klein, Allon; Lewin, Harris; Lowe, Christopher J.; Marlow, Heather; Musser, Jacob M.; Nagy, Laszlo G.; Najle, Sebastian R.; Pachter, Lior; Paez, Sadye; Papatheodorou, Irene; Passalacqua, Michael J.; Rajewsky, Nikolaus; Rhee, Seung Y.; Richards, Thomas A.; Sauka-Spengler, Tatjana; Saunders, Lauren M.; Seuntjens, Eve; Solana, Jordi; Song, Yuyao; Technau, Ulrich; Wang, Bo; Biodiversity Cell Atlas meeting participants
  作者单位：Pompeu Fabra University; Barcelona Institute of Science & Technology; Centre de Regulacio Genomica (CRG); Wellcome Trust Sanger Institute; Pompeu Fabra University; ICREA; Weizmann Institute of Science; Weizmann Institute of Science; European Molecular Biology Laboratory (EMBL); Flanders Institute for Biotechnology (VIB); KU Leuven; Dalhousie University; Stazione Zoologica Anton Dohrn; Carnegie Institution for Science; Johns Hopkins University; Yale University; Universitat Politecnica de Catalunya; Barcelona Supercomputer Center (BSC-CNS); Barcelona Institute of Science & Technology; Institute for Research in Biomedicine - IRB Barcelona; University of Toronto; University of Toronto; Columbia University; Howard Hughes Medical Institute; Universidad Politecnica de Madrid; Harvard University; Harvard Medical School; Arizona State University; Arizona State University-Tempe; University of California System; University of California Davis; Stanford University; University of Chicago; Yale University; Yale University; HUN-REN; HUN-REN Biological Research Center; California Institute of Technology; California Institute of Technology; Rockefeller University; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); Earlham Institute; University of East Anglia; Cold Spring Harbor Laboratory; Helmholtz Association; Max Delbruck Center for Molecular Medicine; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; German Centre for Cardiovascular Research; Michigan State University; Michigan State University; Michigan State University; Michigan State University; University of Oxford; Stowers Institute for Medical Research; University of Oxford; Ruprecht Karls University Heidelberg; KU Leuven; University of Exeter; University of Exeter; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; University of Vienna; Stanford University
  摘要：Cell types are fundamental functional units that can be traced across the tree of life. Rapid advances in single-cell technologies, coupled with the phylogenetic expansion in genome sequencing, present opportunities for the molecular characterization of cells across a broad range of organisms. Despite these developments, our understanding of eukaryotic cell diversity remains limited and we are far from decoding this diversity from genome sequences. Here we introduce the Biodiversity Cell Atlas...
• Rare comet photobombs telescope's view of the cosmos AI翻译
  作者：[Anonymous]
• In situ light-field imaging of octopus locomotion reveals simplified control (06 Aug, 10.1038/s41586-025-09379-z, 2025) AI翻译
  作者：Katija, Kakani; Huffard, Christine L.; Roberts, Paul L. D.; Daniels, Joost; Erickson, Jon; Klimov, Denis; Ruhl, Henry A.; Sherman, Alana D.