2025

最新文章

• Extreme confinement unleashes water's hidden electrical capabilities AI翻译
  作者：Domingo, Neus; Verdaguer, Albert
  作者单位：United States Department of Energy (DOE); Oak Ridge National Laboratory; Center for Nanophase Materials Sciences; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Ciencia de Materiales de Barcelona (ICMAB)
• Tracing the ancestry of barley in time and space AI翻译
  作者：Guo, Yu; Mascher, Martin
  作者单位：Leibniz Institut fur Pflanzengenetik und Kulturpflanzenforschung
• Parachutes inspired by the Japanese art of kirigami AI翻译
  作者：Brun, Pierre-Thomas
  作者单位：KU Leuven
  摘要：Cutting a pattern into a flat disc can transform it into a parachute capable of carrying small payloads, which might be used to deliver humanitarian aid.
• Pre-rRNA spatial distribution and functional organization of the nucleolus AI翻译
  作者：Pan, Yu-Hang; Shan, Lin; Zhang, Yu-Yao; Yang, Zheng-Hu; Zhang, Yuan; Cao, Shi-Meng; Liu, Xiao-Qi; Zhang, Jun; Yang, Li; Chen, Ling-Ling
  作者单位：Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; University of Chinese Academy of Sciences, CAS; Fudan University; Fudan University; ShanghaiTech University; Shanghai Jiao Tong University
  摘要：The multilayered nucleolus is the primary site of ribosome biogenesis(1,2), where successive maturation of small (SSU)(3,4) and large (LSU)(5) ribosomal subunit precursors occurs. However, the spatiofunctional relationship between pre-rRNA processing and nucleolar substructures and how this adapts to changing cellular physiological demands have remained incompletely understood(6,7). Here our spatiotemporal analyses revealed a compartment-specific ribosomal subunit processing in human nucleoli,...
• Quantum correlations enhance the sensitivity of room-temperature sensors AI翻译
  作者：Scharnagl, Maja S.; Hammerer, Klemens
  作者单位：Leibniz University Hannover; Austrian Academy of Sciences
• A new paradigm for outer membrane protein biogenesis in the Bacteroidota AI翻译
  作者：Liu, Xiaolong; Orenday Tapia, Luis; Deme, Justin C.; Lea, Susan M.; Berks, Ben C.
  作者单位：University of Oxford; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); St Jude Children's Research Hospital
  摘要：In Gram-negative bacteria, the outer membrane is the first line of defence against antimicrobial agents and immunological attacks1. A key part of outer membrane biogenesis is the insertion of outer membrane proteins by the beta-barrel-assembly machinery (BAM)2, 3-4. Here we report the cryo-electron microscopy structure of a BAM complex isolated from Flavobacterium johnsoniae, a member of the Bacteroidota, a phylum that includes key human commensals and major anaerobic pathogens. This BAM compl...
• Bacteria use a decoy defence molecule to set a trap for viruses AI翻译
  作者：White, Malcolm F.
  作者单位：University of St Andrews
• Evolution of drug-resistant ovarian-cancer clones tracked in patients AI翻译
  作者：Williams, Marc J.; Shah, Sohrab P.
  作者单位：Memorial Sloan Kettering Cancer Center
  摘要：After an initial treatment response, most ovarian cancers recur because of drug-resistant cell populations. Blood-based tracking, used to monitor clonal evolution in 18 patients, shows that drug-resistant clones are already present at diagnosis, expand during therapy and contain distinctive genomic alterations that have potential therapeutic relevance.
• Universities under fire must harness more of the financial value they create AI翻译
  作者：Huang, Yasheng
  作者单位：Massachusetts Institute of Technology (MIT)
• Reactions in hyperspace AI翻译
  作者：Robinson, William E.
  作者单位：Radboud University Nijmegen