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作者:Phillips, Oliver; Duque, Alvaro; Rodriguez, Lillian; Zo-Bi, Irie Casimir
作者单位:University of Leeds; Universidad Nacional de Colombia; University of the Philippines System; University of the Philippines Manila; Institut National Polytechnique Felix Houphouet-Boigny
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作者:[Anonymous]
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作者:Fischer, Nicola M.; Dumville, Imogen; Nabholz, Benoit; Zhelyazkova, Violeta; Stecker, Ruth-Marie; Blomberg, Anna S.; Dool, Serena E.; Fritze, Marcus; Tilak, Marie-Ka; Bashta, Andriy-Taras; Chenal, Clothilde; Fiston-Lavier, Anna-Sophie; Puechmaille, Sebastien J.
作者单位:Universitat Greifswald; Universite de Montpellier; Institut de Recherche pour le Developpement (IRD); Universite PSL; Centre National de la Recherche Scientifique (CNRS); Ecole Pratique des Hautes Etudes (EPHE); Institut Universitaire de France; Bulgarian Academy of Sciences; University of Turku; University of Helsinki; INRAE; CIRAD; Universite de Montpellier; Institut Agro; Universite de Montpellier; CIRAD; National Academy of Sciences Ukraine; Institute of Ecology of Carpathians; CIRAD; Universite de Montpellier; Institut de Recherche pour le Developpement (IRD); Institut de Recherche pour le Developpement (IRD); Universite de Montpellier; CIRAD
摘要:The emergence of infectious diseases, particularly those caused by fungal pathogens, poses serious threats to public health, wildlife and ecosystem stability1. Host-fungus interactions and environmental factors have been extensively examined2, 3-4. However, the role of genetic variability in pathogens is often less well-studied, even for diseases such as white-nose in bats, which has caused one of the highest disease-driven death tolls documented in nonhuman mammals5. Previous research on whit...
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作者:Goncalves, Renata L. S.; Wang, Zeqiu Branden; Riveros, Jillian K.; Parlakgul, Gunes; Inouye, Karen E.; Lee, Grace Yankun; Fu, Xiaorong; Saksi, Jani; Rosique, Clement; Hui, Sheng Tony; Coll, Mar; Arruda, Ana Paula; Burgess, Shawn C.; Graupera, Isabel; Hotamisligil, Goekhan S.
作者单位:Harvard University; Harvard T.H. Chan School of Public Health; University of Texas System; University of Texas Southwestern Medical Center; CIBER - Centro de Investigacion Biomedica en Red; CIBEREHD; University of Barcelona; Hospital Clinic de Barcelona; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of California System; University of California Berkeley
摘要:Mitochondrial reactive oxygen species (mROS) are central to physiology1,2. Excess mROS production has been associated with several disease states2,3; however, the precise sources, regulation and mechanism of generation in vivo remain unclear, which limits translational efforts. Here we show that in obesity, hepatic coenzyme Q (CoQ) synthesis is impaired, which increases the CoQH2 to CoQ (CoQH2/CoQ) ratio and drives excessive mROS production through reverse electron transport (RET) from site IQ...
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作者:[Anonymous]
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作者:McJeon, Haewon
作者单位:Korea Advanced Institute of Science & Technology (KAIST)
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作者:Tollefson, Jeff; Garisto, Dan; Kozlov, Max; Witze, Alexandra
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作者:[Anonymous]
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作者:Narayanamurti, Venkatesh; Currall, Steven C.
作者单位:Harvard University; Harvard University; Harvard University; State University System of Florida; University of South Florida
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作者:[Anonymous]
摘要:Lithium that pooled in a volcanic caldera in the western United States had no way out, thanks to a lack of rivers.