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• Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate AI翻译
  作者：Ko, Donghwi; Ruonala, Raili; Faille, Alexandre; Hellmann, Eva; Help, Hanna; Liu, Huili; Nielsen, Ronni; Haakonsson, Anders; De Diego, Nuria; Paatero, Anja; Shcherbii, Mariia V.; Stefanowicz, Karolina; Cavar Zeljkovic, Sanja; Drud Lundager Rasmussen, Tine; Novak, Ondrej; Bodi, Zsuzsanna; Eswaran, Gugan; Wybouw, Brecht; Bourdon, Matthieu; Urbez, Cristina; Liu, Xiaonan; Salokas, Kari; Ohman, Tiina; Waldie, Tanya; Toronen, Petri; El-Showk, Sedeer; Balcerowicz, Martin; Besnard, Fabrice; Liu, Xiaomin; Perkins, Patrick; Mazzoni-Putman, Serina; Vainonen, Julia P.; Sierla, Maija; Frilander, Mikko J.; Mandrup, Susanne; Vernoux, Teva; Ljung, Karin; Ferrando, Alejandro; Blazquez, Miguel A.; Holm, Liisa; Fray, Rupert; Varjosalo, Markku; Leyser, Ottoline; Paavilainen, Ville O.; Mahonen, Ari Pekka; Stepanova, Anna; Alonso, Jose; Heber, Steffen; Malinowski, Robert; Kirpekar, Finn; Warren, Alan J.; Helariutta, Yka
  作者单位：University of Helsinki; University of Cambridge; University of Helsinki; University of Cambridge; University of Cambridge; South China Agricultural University; University of Southern Denmark; Palacky University Olomouc; Polish Academy of Sciences; Institute of Plant Genetics of the Polish Academy of Sciences; Czech Academy of Sciences; Palacky University Olomouc; Institute of Experimental Botany of the Czech Academy of Sciences; Palacky University Olomouc; University of Nottingham; Consejo Superior de Investigaciones Cientificas (CSIC); Universitat Politecnica de Valencia; CSIC-UPV - Instituto de Biologia Molecular y Celular de Plantas (IBMCP); University of Dundee; Ecole Normale Superieure de Lyon (ENS de LYON); Universite Lyon 1; Centre National de la Recherche Scientifique (CNRS); INRAE; North Carolina State University; North Carolina State University; Umea University; Swedish University of Agricultural Sciences; University of Cambridge; University of Cambridge; University of Tartu; Friedrich Miescher Institute for Biomedical Research; University of Cambridge
  摘要：Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In Arabidopsis, the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SUPPRESSOR-OF-ACAULIS51 (SAC51) and SAC51-LIKEs (SACLs), which inhibit heterodimerization of the xylem development proteins LONESOME-HIGHWAY (LHW) and TARGET-OF-MONOPTEROS5. Here, we report a methyltransferase, OVERACHIEVER, that methylates the peptidyl transferase center of the 25S ribosomal RNA (r...
• Keeping cells fit AI翻译
  作者：Rambout, Xavier; Maquat, Lynne E.
  作者单位：University of Rochester; University of Rochester
• As the world warms, freezing rain shifts to US South AI翻译
  作者：Richter, Hannah
• Increasing applied pesticide toxicity trends counteract the global reduction target to safeguard biodiversity AI翻译
  作者：Wolfram, Jakob; Bussen, Dino; Bub, Sascha; Petschick, Lara L.; Herrmann, Larissa Z.; Schulz, Ralf
  作者单位：RPTU University Kaiserslautern
  摘要：The 15th United Nations Biodiversity Conference (COP15) obligates all countries to reduce pesticide risks by 50% by 2030. In this study, we derived the trends of total applied toxicity (TAT) globally between 2013 and 2019, weighting applied masses by ecotoxicity, of 625 pesticides for eight species groups to assess pathways toward this reduction goal. We found that the TAT of most species groups has increased; that only 20 +/- 14 pesticides per group define >90% of the TAT nationally; that fru...
• Atomically resolved two-dimensional amorphous nuclei formed during MoS2 chemical vapor deposition AI翻译
  作者：Ye, Huanyu; Wu, Chongteng; Cao, Duanyun; Zhang, Guorui; Sun, Yinghui; Zhu, Yuchen; Wu, Feng; Zhang, Zhihong; Wang, Rongming
  作者单位：University of Science & Technology Beijing; Beijing Institute of Technology; Beijing Institute of Technology; Beijing Institute of Technology; Peking University; Peking University
  摘要：Control over the nucleation and growth of two-dimensional (2D) materials is essential for their scalable manufacturing. We report in situ atomic-scale observations of molybdenum disulfide (MoS2) nucleation and growth through chemical vapor deposition (CVD) using environmental transmission electron microscopy. Coupled with molecular dynamics simulations, our observations reveal the formation of a 2D amorphous structure at the initial nucleation stage, which undergoes an in-plane structural orde...
• High-precision tracking of human foragers reveals adaptive social information use in the wild AI翻译
  作者：Schakowski, Alexander; Deffner, Dominik; Kortet, Raine; Niemela, Petri T.; Kavelaars, Marwa M.; Monk, Christopher T.; Pykala, Maria; Kurvers, Ralf H. J. M.
  作者单位：Max Planck Society; Humboldt University of Berlin; Philipps University Marburg; Technical University of Berlin; University of Eastern Finland; University of Helsinki; Humboldt University of Berlin; Helmholtz Association; GEOMAR Helmholtz Center for Ocean Research Kiel; Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); University of Lausanne
  摘要：Foraging complexity and competitive social challenges are considered key drivers of human cognition. Yet, the decision-making mechanisms that underlie social foraging in the real world remain unknown. Integrating high-precision Global Positioning System (GPS) tracking and video footage from large-scale foraging competitions with cognitive-computational modeling and agent-based simulations, we show how foragers integrate personal, social, and ecological information to guide spatial search and p...
• Tethered platelets in severe infection AI翻译
  作者：Perrella, Gina; Rayes, Julie
  作者单位：University of Birmingham
• A free-floating-planet microlensing event caused by a Saturn-mass object AI翻译
  作者：Dong, Subo; Wu, Zexuan; Ryu, Yoon-Hyun; Udalski, Andrzej; Mroz, Przemek; Rybicki, Krzysztof A.; Hodgkin, Simon T.; Wyrzykowski, Lukasz; Eyer, Laurent; Bensby, Thomas; Chen, Ping; Wang, Sharon X.; Gould, Andrew; Yang, Hongjing; Albrow, Michael D.; Chung, Sun-Ju; Han, Cheongho; Hwang, Kyu-Ha; Jung, Youn Kil; Shin, In-Gu; Shvartzvald, Yossi; Yee, Jennifer C.; Zang, Weicheng; Kim, Dong-Jin; Lee, Chung-Uk; Park, Byeong-Gon; Poleski, Radoslaw; Skowron, Jan; Szymanski, Michal K.; Soszynski, Igor; Pietrukowicz, Pawel; Kozlowski, Szymon; Skowron, Dorota M.; Ulaczyk, Krzysztof; Gromadzki, Mariusz; Ratajczak, Milena; Iwanek, Patryk; Wrona, Marcin; Mroz, Mateusz J.; Rixon, Guy; Harrison, Diana L.; Breedt, Elme
  作者单位：Peking University; Peking University; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; National Astronomical Observatory, CAS; Korea Astronomy & Space Science Institute (KASI); University of Warsaw; Weizmann Institute of Science; University of Cambridge; University of Geneva; Lund University; Zhejiang University; Zhejiang University; Tsinghua University; Max Planck Society; University System of Ohio; Ohio State University; Westlake University; University of Canterbury; Chungbuk National University; Smithsonian Institution; University of Warwick; Villanova University; University of Cambridge
  摘要：A population of free-floating planets is known from gravitational microlensing surveys. None have a directly measured mass, owing to a degeneracy with the distance, but the population statistics indicate that many are less massive than Jupiter. We report a microlensing event-KMT-2024-BLG-0792/OGLE-2024-BLG-0516, which was observed from both ground- and space-based telescopes-that breaks the mass-distance degeneracy. The event was caused by an object with 0.219-0.046+0.075 Jupiter masses that i...
• Limiting phosphonic acid interlayer-perovskite reactivity to stabilize perovskite solar modules AI翻译
  作者：Fei, Chengbin; Zhang, Yadong; Wang, Mengru; Yang, Yuqian; Shi, Xiaoqiang; Wang, Shaojie; Guo, Huanxin; Guo, Chuanhang; Liu, He; Li, Mingze; Gu, Hangyu; Barlow, Stephen; You, Wei; Wang, Mengen; Marder, Seth R.; Huang, Jinsong
  作者单位：University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of Colorado System; University of Colorado Boulder; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder
  摘要：Phosphonic acid (PA)-based interlayers used in metal-halide perovskite solar cells (PSCs) can suffer from instability at elevated temperatures. We report that the acidic protons of PAs weakly bound to indium tin oxide (ITO) can accelerate the oxidation of iodide, decomposition of formamidinium, and reduction of lead ions and that these reactions accelerate at high temperature and on exposure to ultraviolet light. Also, some common PA molecules weakly bonded to ITO can desorb and react with per...
• De novo design of small molecule-regulated protein oligomers AI翻译
  作者：Jin, Qihan; Wang, Yukai; Chen, Dachuan; Liao, Jinyang; Cui, Zhanyuan; Fan, Yuxuan; Zeng, Anping; Xie, Mingqi; Cao, Longxing
  作者单位：Fudan University; Westlake University; Westlake University; Westlake Laboratory; Westlake University; Westlake University; Westlake University; Westlake University; Westlake University; Westlake University; Westlake Laboratory
  摘要：Small molecule-regulated protein oligomerization provides a powerful mechanism for manipulating biological processes by controlling protein proximity with high temporal precision. However, such systems only rarely exist in nature and remain a substantial challenge for de novo design. In this work, we describe a computational method for designing protein homooligomers whose assembly is regulated by small-molecule ligands with matching symmetry. We designed protein homotrimers regulated by the F...