Science

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• US tariffs jeopardize medicine supply chains AI翻译
  作者：Casiraghi, Giona; Andres, Georges; Schweitzer, Frank; Verginer, Luca
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich
• La- and Mn-doped cobalt spinel oxygen evolution catalyst for proton exchange membrane electrolysis (vol. 380, pg. 609, 2023) AI翻译
  作者：Chong, L.
• Global importance of nitrogen fixation across inland and coastal waters AI翻译
  作者：Fulweiler, Robinson W.; Rinehart, Shelby; Taylor, Jason; Kelly, Michelle C.; Berberich, Megan E.; Ray, Nicholas E.; Oczkowski, Autumn; Balint, Sawyer; Benavides, Mar; Church, Matthew J.; Loeks, Brianna; Newell, Silvia; Olofsson, Malin; Oppong, Jimmy Clifford; Roley, Sarah S.; Vizza, Carmella; Wilson, Samuel T.; Chowdhury, Subhadeep; Groffman, Peter; Scott, J. Thad; Marcarelli, Amy M.
  作者单位：Boston University; Boston University; Drexel University; United States Department of Agriculture (USDA); Michigan Technological University; University of Delaware; United States Environmental Protection Agency; NERC National Oceanography Centre; University of Southampton; Centre National de la Recherche Scientifique (CNRS); Institut de Recherche pour le Developpement (IRD); Aix-Marseille Universite; Aix-Marseille Universite; University of Montana System; University of Montana; University of Minnesota System; University of Minnesota Twin Cities; University of Michigan System; University of Michigan; Swedish University of Agricultural Sciences; Charles University Prague; Washington State University; Hawaii Pacific University; Newcastle University - UK; City University of New York (CUNY) System; Brooklyn College (CUNY); Cary Institute of Ecosystem Studies; Baylor University
  摘要：Biological nitrogen fixation is a key driver of global primary production and climate. Decades of effort have repeatedly updated nitrogen fixation estimates for terrestrial and open ocean systems, yet other aquatic systems in between have largely been ignored. Here we present an evaluation of nitrogen fixation for inland and coastal waters. We demonstrate that water column and sediment nitrogen fixation is ubiquitous across these diverse aquatic habitats, with rates ranging six orders of magni...
• DNA in the air could track biodiversity-and humans AI翻译
  作者：Cornwall, Warren
• Scaling plant responses to heat: From molecules to the biosphere AI翻译
  作者：Evans, Margaret E. K.; Hu, Jia; Michaletz, Sean T.
  作者单位：University of Arizona; University of Arizona; University of British Columbia; University of British Columbia; Oregon State University
  摘要：Predicting plant responses to rising temperatures, including acute heat waves and hot droughts of varying intensity and duration, is central to addressing the climate and biodiversity crises. However, plant responses to heat are scale-dependent, complicating cross-scale prediction. We highlight recent progress revealing how and why plant responses to heat change across scales, including scales of biological organization and space versus time. We give examples of scaling up from molecular- and ...
• Global nitrogen budget revisited AI翻译
  作者：Brezonik, Patrick L.
  作者单位：University of Minnesota System; University of Minnesota Twin Cities
• A metabolite-based resistance mechanism against malaria AI翻译
  作者：Figueiredo, Ana; Rastogi, Sonia Trikha; Ramos, Susana; Nogueira, Fatima; De Villiers, Katherine; de Sousa, Antonio G. Goncalves; Votborg-Novel, Lasse; von Wedel, Cacilie; Tober-Lau, Pinkus; Jentho, Elisa; Pagnotta, Sara; Mesquita, Miguel; Cardoso, Silvia; Bortolussi, Giulia; Muro, Andres F.; Tranfield, Erin M.; Thibaud, Jessica; Duarte, Denise; Sousa, Ana Laura; Pinto, Sandra N.; Kitoko, Jamil; Mombo-Ngoma, Ghyslain; Mischlinger, Johannes; Junttila, Sini; Alenquer, Marta; Amorim, Maria Joao; Vasavda, Chirag; Bosma, Piter J.; Violante, Sara; Drotleff, Bernhard; Paixao, Tiago; Portugal, Silvia; Kurth, Florian; Elo, Laura L.; Paul, Bindu D.; Martins, Rui; Soares, Miguel P.
  作者单位：Instituto Superior de Ciencias da Saude Egas Moniz; Universidade Nova de Lisboa; Institute of Hygiene & Tropical Medicine - UNL; Stellenbosch University; University of Turku; Abo Akademi University; Max Planck Society; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Free University of Berlin; Humboldt University of Berlin; Friedrich Schiller University of Jena; International Center for Genetic Engineering & Biotechnology (ICGEB); Universidade de Lisboa; Universidade de Lisboa; Leibniz Association; Bernhard Nocht Institut fur Tropenmedizin; University of Hamburg; University Medical Center Hamburg-Eppendorf; University of Hamburg; University Medical Center Hamburg-Eppendorf; Universidade Catolica Portuguesa; Johns Hopkins University; University of Amsterdam; European Molecular Biology Laboratory (EMBL); University of Turku; Johns Hopkins University; Johns Hopkins University; Flanders Institute for Biotechnology (VIB); Ghent University; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School
  摘要：Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an adaptive or maladaptive response to Plasmodium spp. infection. We found that asymptomatic P. falciparum infection in humans was associated with a higher ratio of unconjugated over conjugated bilirubin and parasite burden compared with symptomatic malaria. Genetic suppression of bilirubin synthesis by biliverdin reductase ...
• RNA transcripts regulate G-quadruplex landscapes through G-loop formation AI翻译
  作者：Sato, Koichi; Lyu, Jing; van den Berg, Jeroen; Braat, Diana; Cruz, Victoria M.; Navarro Luzon, Carmen; Schimmel, Joost; Esteban-Jurado, Clara; Alemany, Maelys; Dreyer, Jan; Hendrikx, Aiko; Mattiroli, Francesca; van Oudenaarden, Alexander; Tijsterman, Marcel; Elsasser, Simon J.; Knipscheer, Puck
  作者单位：Royal Netherlands Academy of Arts & Sciences; Hubrecht Institute (KNAW); Utrecht University; Utrecht University Medical Center; Leiden University; Leiden University Medical Center (LUMC); Leiden University - Excl LUMC; Karolinska Institutet; Karolinska Institutet; Royal Netherlands Academy of Arts & Sciences; Hubrecht Institute (KNAW); Leiden University; Leiden University - Excl LUMC
  摘要：G-quadruplexes (G4s) are prevalent DNA structures that regulate transcription but also threaten genome stability. How G4 dynamics are controlled remains poorly understood. Here, we report that RNA transcripts govern G4 landscapes through coordinated G-loop assembly and disassembly. G-loop assembly involves activation of the ATM and ATR kinases, followed by homology-directed invasion of RNA opposite the G4 strand mediated by BRCA2 and RAD51. Disassembly of the G-loop resolves the G4 structure t...
• Acid-humidified CO2 gas input for stable electrochemical CO2 reduction reaction AI翻译
  作者：Hao, Shaoyun; Elgazzar, Ahmad; Zhang, Shou-Kun; Wi, Tae-Ung; Chen, Feng-Yang; Feng, Yuge; Zhu, Peng; Wang, Haotian
  作者单位：Rice University; Rice University; Rice University; Rice University; Rice University
  摘要：(Bi)carbonate salt formation has been widely recognized as a primary factor in poor operational stability of the electrochemical carbon dioxide reduction reaction (CO2RR). We demonstrate that flowing CO2 gas into an acid bubbler-which carries trace amounts of acid vapor into a gas diffusion electrode for silver-catalyzed CO2RR to carbon monoxide (CO)-can prevent salt accumulation. In a 100-square-centimeter, scaled-up CO2RR membrane electrode assembly electrolyzer with single serpentine flow c...
• Plants Facing the Heat AI翻译
  作者：Seale, Madeleine; Lopez, Bianca; Lempriere, Sarah