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作者:Tang, Xing-Zhou; Li, Chao-Yi; Huang, Zhi-Jun; Zhao, Jia-Hui; Chen, Yu-Xi; Abbott, Nicholas L.; de Pablo, Juan J.; Lu, Yan-Qing; Li, Bing-Xiang
作者单位:Nanjing University of Posts & Telecommunications; Nanjing University of Posts & Telecommunications; University of Chicago; Nanjing University; Nanjing University; Collaborative Innovation Center of Advanced Microstructures (CICAM); Cornell University; United States Department of Energy (DOE); Argonne National Laboratory; New York University; New York University Tandon School of Engineering
摘要:Reflection and refraction are ubiquitous phenomena with extensive applications, yet minimizing energy loss and information distortion during these processes remains a significant challenge. This study examines the behavior of structurally stable solitons, known as directrons, in nematic liquid crystals interacting with an interface where the director field orientation changes, despite identical physical properties, external potentials, and boundary anchoring in the two regions. During reflecti...
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作者:Guo, Jiani; Liu, Mengyao; Liu, Feng; Wang, Lu
作者单位:Chinese Academy of Medical Sciences - Peking Union Medical College; Institute of Hematology & Blood Diseases Hospital - CAMS; Peking Union Medical College; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Institute of Zoology, CAS
摘要:The tightly controlled spatiotemporal expression of developmental genes depends on the concerted action of cis-regulatory elements (CREs) and transcription factors (TFs) to ensure cell fate decisions. Endothelial-to-hematopoietic transition (EHT) is a cell fate transition process by which endothelial cells acquire hematopoietic identity and become hemogenic endothelial cells (HECs) and then hematopoietic stem and progenitor cells, but the underlying CRE network dynamics and its regulation by T...
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作者:Van der Meersch, Victor; Wolkovich, E. M.
作者单位:University of British Columbia; Universite PSL; Ecole Pratique des Hautes Etudes (EPHE); Institut Agro; Montpellier SupAgro; CIRAD; Centre National de la Recherche Scientifique (CNRS); Institut de Recherche pour le Developpement (IRD); Universite Paul-Valery; Universite de Montpellier
摘要:Multiple studies have recently proposed the summer solstice as a universal cue for major plant physiological processes. While this would have strong implications for fundamental plant biology and climate change forecasting, we currently have no clear mechanisms to explain the emergence and importance of solstice as a cue. Here, we analyze temperature accumulation patterns in relation to the summer solstice across Europe and North America-in past, historical, and projected future climates. We s...
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作者:Vergish, Satyam; Huang, Xiaoen; Zhang, Guiyun; Franceschi, Beatriz de Toledo; Li, Jian-Liang; Wu, Xiao-Xia; Nuraj, Joana; Huguet-Tapia, Jose C.; Parajuli, Apekshya; Chen, Xiuhua; Shekhar, Ritu; Liu, Dali; Xiao, Wu-Ming; Dou, Shijuan; Liu, Guo-zhen; Goss, Erica M.; Pi, Liya; Chen, Sixue; Koch, Karen E.; Song, Wen- Yuan
作者单位:State University System of Florida; University of Florida; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); State University System of Florida; University of Florida; Hebei Agricultural University; State University System of Florida; University of Florida; Tulane University; University of Mississippi; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; Yangzhou University; State University System of Florida; Florida International University; Heilongjiang University; South China Agricultural University
摘要:To maintain growth and to successfully reproduce, organisms must protect key functions in specific tissues, particularly when countering pathogen invasion using internal defensive proteins that may disrupt their own developmental processes. The rice immune receptor XA21 confers race-specific resistance against Xanthomonas oryzae pv. oryzae, which causes the deadly disease bacterial leaf blight. Here, we demonstrate that XA21 is cleaved by the rhomboid-like protease OsRBL3b, likely within its t...
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作者:Lawrence, William M.; Blake, Geoffrey A.; Eiler, John
作者单位:California Institute of Technology
摘要:Macromolecular organic solids found in primitive meteorites were the main source of carbon delivered to forming planets in the early Solar System. However, the conditions under which this material formed and its subsequent incorporation into growing planetesimals remains a subject of vigorous debate. Here, we show that C isotope variations among these organics in most carbonaceous chondrites are strongly correlated with mass-independent O isotope anomalies exhibited by their host meteorites. A...
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作者:Wang, Xixian; Wang, Sen; Diao, Zhidian; Hou, Xibao; Gong, Yanhai; Sun, Qing; Zhang, Jiaping; Ren, Lihui; Li, Yuandong; Ji, Yuetong; Shen, Wei; Yin, Yifeng; Huang, Shi; Song, Xiaojin; Cui, Qiu; Feng, Yingang; Xu, Jian; Ma, Bo
作者单位:Chinese Academy of Sciences; Qingdao Institute of Bioenergy & Bioprocess Technology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Hong Kong
摘要:A full spontaneous single-cell Raman spectrum captures the metabolic phenome in a label-free and noninvasive manner. However, Raman-activated cell sorting (RACS) of rare target cells from highly heterogeneous systems has remained largely conceptual. Here, we present a positive dielectrophoresis-induced deterministic lateral displacement (pDEP-DLD)-based RACS (pDEP-DLD-RACS), in which a modulated pDEP-DLD force is applied to focus, trap, and functionally sort fast-moving single cells in a wide ...
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作者:Moutouama, Jacob K.; Compagnoni, Aldo; Miller, Tom E. X.
作者单位:Rice University; Martin Luther University Halle Wittenberg; German Research Foundation (DFG); German Centre for Integrative Biodiversity Research (iDiv)
摘要:Global climate change has triggered an urgent need for predicting the reorganization of Earth's biodiversity. For dioecious species (those with separate sexes), it is unclear how commonly unique climate sensitivities of females and males could influence projections for species-level responses to climate change. We developed demographic models of range limitation, parameterized from geographically distributed common garden experiments, with females and males of a dioecious grass species (Poa ar...
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作者:Morrison, Robin E.; Ellis, Samuel; Martignac, Victoire; Stoinski, Tara S.; Eckardt, Winnie
作者单位:University of Zurich; University of Exeter
摘要:Evidence across a broad range of disciplines has demonstrated how individuals' social environments can impact their health, lifespan, reproduction, and ultimately their evolutionary fitness. Past research has primarily focused on either traits specific to individuals or wider traits of social groups, linking these with a component of fitness. In this study, we examined how both individual-and group-level social traits in 164 wild mountain gorillas combine to influence multiple pathways impacti...
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作者:Hand, Suzanne J.; Wilson, Laura A. B.; Lopez-Aguirre, Camilo; Houssaye, Alexandra; Archer, Michael; Bevitt, Joseph J.; Evans, Alistair R.; Halim, Amalia Y.; Hung, Tzong; Rich, Thomas H.; Vickers-Rich, Patricia; Beck, Robin M. D.
作者单位:University of New South Wales Sydney; Australian National University; Australian National University; University of Toronto; University Toronto Scarborough; Universidad de La Salle; Universidad Industrial de Santander; Museum National d'Histoire Naturelle (MNHN); Centre National de la Recherche Scientifique (CNRS); Australian Nuclear Science & Technology Organisation; Monash University; University of New South Wales Sydney; University of New South Wales Sydney; Monash University; University of Salford
摘要:The platypus and four echidna species are the only living egg-laying mammals and the sole extant representatives of Order Monotremata. The platypus and echidnas are very disparate both morphologically and ecologically: The platypus is a specialized semiaquatic burrowing form that forages for freshwater invertebrates, whereas echidnas are fully terrestrial and adapted for feeding on social insects and earthworms. It has been proposed that echidnas evolved from a semiaquatic, platypus-like ances...
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作者:Marang, Christopher P.; Petersen, Daniel J.; Scott, Brent D.; Walcott, Sam; Debold, Edward P.
作者单位:University of Massachusetts System; University of Massachusetts Amherst; Worcester Polytechnic Institute; Worcester Polytechnic Institute; Worcester Polytechnic Institute
摘要:Intensely contracting fast skeletal muscle rapidly loses the ability to generate force, due in part to the accumulation of phosphate (Pi) inhibiting myosin's force-generating capacity, in a process that is strain dependent. Crucial aspects of the mechanism underlying this inhibition remain unclear. Therefore, we directly determined the effects of increasing [Pi] on rabbit psoas muscle myosin's ability to generate force against progressively higher resistive loads in a laser trap assay, with th...