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作者：Li, Kejian; Dong, Wan Jae; Shen, Rui; Ye, Zhengwei; Zhang, Bingxing; Pan, Yuyang; Xia, Deming; Wang, Chunhua; Francisco, Joseph S.; Mi, Zetian
作者单位：University of Michigan System; University of Michigan; Korea University; Korea Institute of Science & Technology (KIST); University of Pennsylvania
摘要：Artificial N2 reduction offers a sustainable approach to green NH3 synthesis, but the practical implementation is challenged by N2 activation and competing hydrogen evolution. Photoelectrochemical nitrate and nitrite (NOx-, x = 2 and 3) reduction with favorable thermodynamics represents a promising alternative for NH3 production, provided that NOx-can be supplied from the atmosphere. Here, through leveraging water microdroplet chemistry and dynamic photoelectrode-electrolyte interface engineer...
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作者：Liu, Yonghao; Zheng, Yuan; Yang, Kun; Zhang, Wenhao; Wu, Zongxiu; Gao, Jingjing; Luo, Xuan; Sun, Yuping; Zhang, Jin; Yin, Yi
作者单位：Zhejiang University; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; National Center for Nanoscience & Technology, CAS; Chinese Academy of Sciences; Hefei Institutes of Physical Science, CAS; Chinese Academy of Sciences; Hefei Institutes of Physical Science, CAS; Collaborative Innovation Center of Advanced Microstructures (CICAM); Nanjing University
摘要：We investigate a twisted bilayer of 1T-TaSe2 (twist angle < 4(degrees)) using scanning tunneling microscopy and spectroscopy, revealing that the coexisting twisted atomic lattice and charge density wave (CDW) superlattice generate a dual moire structure with distinct electronic modulation effects: The topographic moire pattern stems from atomic lattice twisting modulating CDW intensity, while the twisted CDW superlattice drives a continuous insulator-to-metal transition, as evidenced by electr...
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作者：Yang, Xue; Jiang, Yi; Zhou, Qianxiang; Pei, Kuan; Guo, Chunyan; Zhang, Peng
作者单位：Capital Normal University; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Psychology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Beihang University; Beihang University; Chinese Academy of Sciences; University of Science & Technology of China, CAS
摘要：The extent to which two brains align during information processing is thought to be central to collaborative memory encoding; however, the neural mechanisms that support such interpersonal alignment remain elusive. Traditional interbrain synchrony models based on phase-alignment metrics fail to distinguish true interbrain connectivity from spurious synchrony driven by shared stimulus processing. Here, we introduce a quantum-inspired framework to capture the connectivity between two collaborati...
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作者：Levine, Matthew S.; Li, Jiexi; Ehrlich, Lauren I. R.; Depinho, Ronald A.; Iverson, Brent; Sessler, Jonathan L.
作者单位：University of Texas System; UTMD Anderson Cancer Center; University of Texas System; University of Texas Austin
摘要：Viral mimicry may be an underappreciated contributor to chemotherapeutic potency in animal models and patients. This hypothesis is based on studies of a bis-Au(I)-NHC complex that was found to generate a strong anti-tumor immune response in vivo in two different challenge studies using an iKAP colorectal cancer mouse model. RNA profiling of treated cells revealed the stimulation of genes that overlap with those upregulated during a viral infection. The bis-Au(I)-NHC complex generates reactive ...
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作者：Han, Yiyuan; Torre, Matthew; Ma, Xiaojing; Xue, Tianrui; Wang, Yuan; Jo, Sooyeon; Fujita, Akie; Bean, Bruce P.; Kohane, Daniel S.
作者单位：Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Boston Children's Hospital; Baylor College of Medicine; Harvard University; Harvard Medical School
摘要：Site 1 sodium channel blockers (S1SCBs), such as tetrodotoxin (TTX) and neosaxitoxin, are ultrapotent local anesthetics with low tissue toxicity. Their duration of action is relatively brief, but increasing the dose can lead to systemic toxicity. Here, we report that selected flavonoids-puerarin (PUE), naringenin, and kaempferol-prolong nerve block from S1SCBs 4-to 25-fold. Using both tympanic membrane (TM) permeation and sciatic nerve fluorescence distribution models, we demonstrate the flavo...
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作者：Li, Wenlong; Sun, Tianxiao; Shah, Sameep Rajubhai; Ju, Zhengyu; Zhou, Jigang; Zhao, Kejie; Yu, Guihua; Liu, Yijin
作者单位：University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; Purdue University System; Purdue University; Purdue University in Indianapolis; General Motors
摘要：Lithium-ion battery formation is a pivotal step that dictates performance, longevity, and manufacturing safety. At the core of this process is the formation and evolution of the solid electrolyte interphase (SEI), whose nanoscale thickness, high environmental sensitivity, and dynamic behavior have long hindered direct characterization. Here, we exploit the SEI-induced refractive index matching effect and utilize operando optical microscopy to directly visualize SEI growth in real time. Our obs...
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作者：Sebastian, John; Jensen, Kaare H.
作者单位：Technical University of Denmark
摘要：Despite their ubiquity in Nature, spikes or stingers rarely exhibit sharp tips. Instead, a closer inspection of their roughly conical tips reveals a striking similarity in their profiles: They adhere to a power-law, z similar to rn, where n approximate to 2. This conformity persists across diverse spatial scales and materials. The mechanistic basis for this universality was recently attributed to evolutionary selection for ease of piercing [H. Quan et al., Proc. Natl. Acad. Sci. U.S.A. 121, e2...
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作者：Silber, Katy M.; Boyle, W. Alice
作者单位：Kansas State University; Western University (University of Western Ontario)
摘要：Precipitation influences animal physiology, behavior, and ecological interactions, therefore affecting demography. However, the nature and strength of those effects vary widely, have been attributed to mechanisms operating over different time scales, and may depend on species-level attributes. We conducted a global meta-analysis accounting for shared evolutionary history to a) understand the nature of relationships between precipitation and avian reproductive success and b) test alternative hy...
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作者：Ganguly, Abira; Zmuda, Hannah; Abello, Javier; Illy, Danielle; Walter, Christopher; Tsatskis, Yonit; Thanintorn, Nattapon; Zhang, Ying; Hakim, Bilal Ahmad; Hodzic, Didier; Stratman, Amber N.; Jurisicova, Andrea; Pathak, Amit; Mcneill, Helen
作者单位：Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); University of Toronto; Hospital for Sick Children (SickKids); University of Toronto; Sinai Health System Toronto; Lunenfeld Tanenbaum Research Institute; University of Toronto; University of Toronto
摘要：Nuclear Envelope Membrane Protein 1 (NEMP1) is crucial for metazoan fertility; loss of Nemp1 causes death of primordial oocytes that reside in the mechanically challenging ovarian cortex. Here, we show that softening the ovary rescues oocyte loss and restores substrates leads to death, while cells remain viable on soft substrates. We further show Mechanistically, Nemp1-depleted cells on stiff substrates or subjected to stretching exhibit reduced nuclear YAP localization, and expressing nuclear...
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作者：Wang, Weihao; Chen, Fangyi; Chen, Zhenghong; Sun, Yutong; Liu, Feng; Zhang, Shaodong
作者单位：Shanghai Jiao Tong University; Xi'an Jiaotong University
摘要：Racemic compounds, consisting of an equimolar mixture of enantiomers in crystalline form, are conventionally regarded as fully symmetric and are often dismissed as a trivial phenomenon due to their abundance-as they account for a substantial fraction (90 to 95%) of entries in structural databases. Here, we uncover the symmetry--breaking hierarchical organization within racemic compounds: single-handed molecules first self--assemble into homochiral domains, which then periodically self--organiz...
