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作者:Babey, Muriel E.; Krause, William C.; Chen, Kun; Herber, Candice B.; Torok, Zsofia; Nikkanen, Joni; Rodriguez, Ruben; Zhang, Xiao; Castro-Navarro, Fernanda; Wang, Yuting; Wheeler, Erika E.; Villeda, Saul; Leach, J. Kent; Lane, Nancy E.; Scheller, Erica L.; Chan, Charles K. F.; Ambrosi, Thomas H.; Ingraham, Holly A.
作者单位:University of California System; University of California San Francisco; University of California System; University of California San Francisco; California State University System; California State University Sacramento; Washington University (WUSTL); Stanford University; Stanford University; University of California System; University of California Davis; University of California System; University of California San Francisco; University of California System; University of California Davis; University of California System; University of California Berkeley
摘要:In lactating mothers, the high calcium (Ca2+) demand for milk production triggers significant bone loss1. Although oestrogen normally counteracts excessive bone resorption by promoting bone formation, this sex steroid drops precipitously during this postpartum period. Here we report that brain-derived cellular communication network factor 3 (CCN3) secreted from KISS1 neurons of the arcuate nucleus (ARCKISS1) fills this void and functions as a potent osteoanabolic factor to build bone in lactat...
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作者:Dang, Qiu-Di; Deng, Yi-Hui; Sun, Tian-Yu; Zhang, Yao; Li, Jun; Zhang, Xia; Wu, Yun-Dong; Niu, Dawen
作者单位:Sichuan University; Sichuan University; Peking University Shenzhen Graduate School (PKU Shenzhen); Peking University; Shenzhen Bay Laboratory
摘要:Oligosaccharides have myriad functions throughout biological processes1,2. Chemical synthesis of these structurally complex molecules facilitates investigation of their functions. With a dense concentration of stereocentres and hydroxyl groups, oligosaccharide assembly through O-glycosylation requires simultaneous control of site, stereo- and chemoselectivities3,4. Chemists have traditionally relied on protecting group manipulations for this purpose5-8, adding considerable synthetic work. Here...
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作者:Soliman, Alix
摘要:Unintended interbreeding between hatchery-bred and wild-born pink salmon could reduce resiliency of fish stocks.
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作者:Soliman, Alix
摘要:High-resolution images of the underside of a formation in Antarctica could help researchers to refine projections of sea-level rise.
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作者:Shao, Hou-Ji; Wang, Yu-Xuan; Zhu, De-Zhi; Zhu, Yan-Song; Sun, Hao-Nan; Chen, Si-Yuan; Zhang, Chi; Fan, Zhi-Jie; Deng, Youjin; Yao, Xing-Can; Chen, Yu-Ao; Pan, Jian-Wei
作者单位:Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Hefei National Laboratory; Chinese Academy of Sciences; University of Science & Technology of China, CAS
摘要:The fermionic Hubbard model (FHM)1 describes a wide range of physical phenomena resulting from strong electron-electron correlations, including conjectured mechanisms for unconventional superconductivity. Resolving its low-temperature physics is, however, challenging theoretically or numerically. Ultracold fermions in optical lattices2,3 provide a clean and well-controlled platform offering a path to simulate the FHM. Doping the antiferromagnetic ground state of a FHM simulator at half-filling...
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作者:Pan, Aline C.; Klas, Juliana
作者单位:Universidade Federal do Rio Grande do Sul
摘要:Letter to the Editor
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作者:Najam, Adil
作者单位:Boston University
摘要:The International Court of Justice is set to clarify the responsibilities of states to act on global warming. Governments must step up in support - before it's too late.
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作者:Nordling, Linda; Abuu, Bahati
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作者:Su, Xiaohua; Chakravarti, Deepavali; Cho, Min Soon; Liu, Lingzhi; Gi, Young Jin; Lin, Yu-Li; Leung, Marco L.; El-Naggar, Adel; Creighton, Chad J.; Suraokar, Milind B.; Wistuba, Ignacio; Flores, Elsa R.
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作者:Ouyang, Yun-Hao; Luan, Hong-Yi; Zhao, Zi-Wei; Mao, Wen-Zhi; Ma, Ren-Min
作者单位:Peking University; Peking University; Peking University; Peking University
摘要:Compressing the optical field to the atomic scale opens up possibilities for directly observing individual molecules, offering innovative imaging and research tools for both physical and life sciences. However, the diffraction limit imposes a fundamental constraint on how much the optical field can be compressed, based on the achievable photon momentum(1,2). In contrast to dielectric structures, plasmonics offer superior field confinement by coupling the light field with the oscillations of fr...