Nature

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• Maize smart-canopy architecture enhances yield at high densities AI翻译
  作者：Tian, Jinge; Wang, Chenglong; Chen, Fengyi; Qin, Wenchao; Yang, Hong; Zhao, Sihang; Xia, Jinljang; Du, Xian; Zhu, Yifan; Wu, Lishuan; Cao, Yan; Li, Hong; Zhuang, Junhong; Chen, Shaojiang; Zhang, Huayuan; Chen, Qiuyue; Zhang, Mingcai; Deng, Xing Wang; Deng, Dezhi; Li, Jigang; Tian, Feng
  作者单位：China Agricultural University; Beijing Academy of Agriculture & Forestry Sciences (BAAFS); China Agricultural University; China Agricultural University; China Agricultural University; North Carolina State University; China Agricultural University; Peking University
  摘要：Increasing planting density is a key strategy for enhancing maize yields(1-3). An ideotype for dense planting requires a 'smart canopy' with leaf angles at different canopy layers differentially optimized to maximize light interception and photosynthesis(4-6), among other features. Here we identified leaf angle architecture of smart canopy 1 (lac1), a natural mutant with upright upper leaves, less erect middle leaves and relatively flat lower leaves. lac1 has improved photosynthetic capacity a...
• Molecular mimicry in multisystem inflammatory syndrome in children AI翻译
  作者：Bodansky, Aaron; Mettelman, Robert C.; Sabatino, Joseph J., Jr.; Vazquez, Sara E.; Chou, Janet; Novak, Tanya; Moffitt, Kristin L.; Miller, Haleigh S.; Kung, Andrew F.; Rackaityte, Elze; Zamecnik, Colin R.; Rajan, Jayant, V; Kortbawi, Hannah; Mandel-Brehm, Caleigh; Mitchell, Anthea; Wang, Chung-Yu; Saxena, Aditi; Zorn, Kelsey; Yu, David J. L.; Pogorelyy, Mikhail, V; Awad, Walid; Kirk, Allison M.; Asaki, James; Pluvinage, John, V; Wilson, Michael R.; Zambrano, Laura D.; Campbell, Angela P.; Thomas, Paul G.; Randolph, Adrienne G.; Anderson, Mark S.; DeRisi, Joseph L.
  作者单位：University of California System; University of California San Francisco; St Jude Children's Research Hospital; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Chan Zuckerberg Initiative (CZI); University of California System; University of California San Francisco; University of California System; University of California San Francisco; Centers for Disease Control & Prevention - USA; Centers for Disease Control & Prevention - USA; University of California System; University of California San Francisco
  摘要：Multisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela of SARS-CoV-2 infection(1,2), yet the pathophysiological mechanism connecting the infection to the broad inflammatory syndrome remains unknown. Here we leveraged a large set of samples from patients with MIS-C to identify a distinct set of host proteins targeted by patient autoantibodies including a particular autoreactive epitope within SNX8, a protein involved in regulating an antiviral pathway associa...
• 'Publish or Perish' is now a card game - not just an academic's life AI翻译
  作者：Kozlov, Max
  摘要：A player wins by racking up more citations than the competition, even if that means engaging in a little light plagiarism.
• Structure of the human dopamine transporter and mechanisms of inhibition AI翻译
  作者：Srivastava, Dushyant Kumar; Navratna, Vikas; Tosh, Dilip K.; Chinn, Audrey; Sk, Md Fulbabu; Tajkhorshid, Emad; Jacobson, Kenneth A.; Gouaux, Eric
  作者单位：Oregon Health & Science University; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK); University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign; Oregon Health & Science University; Howard Hughes Medical Institute; University of Michigan System; University of Michigan
  摘要：The neurotransmitter dopamine has central roles in mood, appetite, arousal and movement(1). Despite its importance in brain physiology and function, and as a target for illicit and therapeutic drugs, the human dopamine transporter (hDAT) and mechanisms by which it is inhibited by small molecules and Zn2+ are without a high-resolution structural context. Here we determine the structure of hDAT in a tripartite complex with the competitive inhibitor and cocaine analogue, (-)-2-beta-carbomethoxy-3...
• Deep crustal assimilation during the 2021 Fagradalsfjall Fires, Iceland AI翻译
  作者：Day, James M. D.; Kelly, Savannah; Troll, Valentin R.; Moreland, William M.; Cook, Geoffrey W.; Thordarson, Thor
  作者单位：University of California System; University of California San Diego; Scripps Institution of Oceanography; Uppsala University; Uppsala University; Centre of Natural Hazards & Disaster Science (CNDS); University of Iceland
  摘要：Active basaltic eruptions enable time-series analysis of geochemical and geophysical properties, providing constraints on mantle composition and eruption processes(1-4). The continuing Fagradalsfjall and Sundhnukur fires on Iceland's Reykjanes Peninsula, beginning in 2021, enable such an approach(5,6). Earliest lavas of this volcanic episode have been interpreted to exclusively reflect a change from shallow to deeper mantle source processes(7). Here we show using osmium (Os) isotopes that the ...
• How to design a protein that can be switched on and off AI翻译
  作者：Wand, A. Joshua
  作者单位：Texas A&M University System; Texas A&M University College Station
  摘要：Proteins have been designed that assemble in different ways depending on whether an 'effector' molecule is present - a demonstration of allostery, the phenomenon that enables switch-like control of protein functions in nature. Designer proteins that exhibit the phenomenon of allostery.
• Multimodal approach steps up the search for axion insulators AI翻译
  作者：Ahn, Youngjun; Zhao, Liuyan
  作者单位：University of Michigan System; University of Michigan; United States Department of Energy (DOE); Argonne National Laboratory
  摘要：A cocktail of experiments and theory provides a way of revealing complex patterns in magnetic materials, including some textures that can identify the systems as members of an elusive class known as axion insulators.
• The Great Barrier Reef is warmer than ever AI翻译
  作者：Pfeiffer, Miriam
  作者单位：University of Kiel
• Blood tests could soon predict your risk of Alzheimer's AI翻译
  作者：Abbott, Alison
  摘要：Scientists are closing in on biomarkers that reflect the progression of Alzheimer's disease and could improve treatments.
• Neuroscience is crucial for transgender people's health AI翻译
  作者：VanderLaan, Doug P.; Huepen, Philippa
  作者单位：University of Toronto; University Toronto Mississauga; RWTH Aachen University