作者：Dolgin, Elie
摘要：Pain is defined subjectively, but an objective measure of the experience promises to transform its management
作者：Garisto, Dan
摘要：Particle measurements at the Large Hadron Collider open the door to future high-energy tests of entanglement. Particle measurements at the Large Hadron Collider open the door to future high-energy tests of entanglement.
作者：Owens, Brian
摘要：Industry research funding is vastly eclipsing academia's spend, but healthy development demands broad input.
作者：Dunn, Michael E.; Kithcart, Aaron; Kim, Jee Hae; Ho, Andre Jo-Hao; Franklin, Matthew C.; Romero Hernandez, Annabel; de Hoon, Jan; Botermans, Wouter; Meyer, Jonathan; Jin, Ximei; Zhang, Dongqin; Torello, Justin; Jasewicz, Daniel; Kamat, Vishal; Garnova, Elena; Liu, Nina; Rosconi, Michael; Pan, Hao; Karnik, Satyajit; Burczynski, Michael E.; Zheng, Wenjun; Rafique, Ashique; Nielsen, Jonas B.; De, Tanima; Verweij, Niek; Pandit, Anita; Locke, Adam; Chalasani, Naga; Melander, Olle; Schwantes-An, Tae-Hwi; Biobank, Penn Medicine; Baras, Aris; Lotta, Luca A.; Musser, Bret J.; Mastaitis, Jason; Devalaraja-Narashimha, Kishor B.; Rankin, Andrew J.; Huang, Tammy; Herman, Gary; Olson, William; Murphy, Andrew J.; Yancopoulos, George D.; Olenchock, Benjamin A.; Morton, Lori
作者单位：Regeneron; KU Leuven; University Hospital Leuven; Regeneron; Indiana University System; Indiana University Bloomington; Indiana University Health; IU Health University Hospital; Lund University; Lund University; Skane University Hospital; Indiana University System; Indiana University Bloomington
摘要：Heart failure is a leading cause of morbidity and mortality 1,2 . Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion 3-8 . Recombinant natriuretic peptide infusions were developed to treat heart failure but have been limited by a short duration of effect 9,10 . Here w...
作者：Mifsud, Jonathon C. O.; Lytras, Spyros; Oliver, Michael R.; Toon, Kamilla; Costa, Vincenzo A.; Holmes, Edward C.; Grove, Joe
作者单位：University of Sydney; University of Glasgow; University of Tokyo
摘要：Viral glycoproteins drive membrane fusion in enveloped viruses and determine host range, tissue tropism and pathogenesis(1). Despite their importance, there is a fragmentary understanding of glycoproteins within the Flaviviridae(2), a large virus family that include pathogens such as hepatitis C, dengue and Zika viruses, and numerous other human, animal and emergent viruses. For many flaviviruses the glycoproteins have not yet been identified, for others, such as the hepaciviruses, the molecul...
作者：Gaind, Nisha
摘要：It was modelled after DARPA, the hugely successful US tech funder. Can Britain's Advanced Research and Invention Agency - ARIA - create revolutionary innovations?
作者：Lee, Juyeun; Lathia, Justin D.
摘要：The human brain is usually considered to be beyond the reach of most immune cells. However, analysis of people who have brain tumours has revealed tumour-targeting T cells of the immune system in skull bones near the cancer site.
