作者:Furuichi, Munehiro; Kawaguchi, Takaaki; Pust, Marie-Madlen; Yasuma-Mitobe, Keiko; Plichta, Damian R.; Hasegawa, Naomi; Ohya, Takashi; Bhattarai, Shakti K.; Sasajima, Satoshi; Aoto, Yoshimasa; Tuganbaev, Timur; Yaginuma, Mizuki; Ueda, Masahiro; Okahashi, Nobuyuki; Amafuji, Kimiko; Kiridoshi, Yuko; Sugita, Kayoko; Strazar, Martin; Avila-Pacheco, Julian; Pierce, Kerry; Clish, Clary B.; Skelly, Ashwin N.; Hattori, Masahira; Nakamoto, Nobuhiro; Caballero, Silvia; Norman, Jason M.; Olle, Bernat; Tanoue, Takeshi; Suda, Wataru; Arita, Makoto; Bucci, Vanni; Atarashi, Koji; Xavier, Ramnik J.; Honda, Kenya
作者单位:Keio University; RIKEN; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; Keio University; Keio University; University of Osaka; Keio University; Waseda University; Keio University; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
摘要:Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine can result from long-term antibiotic use or inflammatory conditions, and may perpetuate dysregulated immunity and tissue damage(1,2). Gram-negative Enterobacteriaceae gut pathobionts are particularly recalcitrant to conventional antibiotic treatment(3,4), although an emerging body of evidence suggests that manipulation of the commensal microbiota may be a practical alternative therapeutic strategy(5-7). ...
作者:Cavalet-Giorsa, Emile; Gonzalez-Munoz, Andrea; Athiyannan, Naveenkumar; Holden, Samuel; Salhi, Adil; Gardener, Catherine; Quiroz-Chavez, Jesus; Rustamova, Samira M.; Elkot, Ahmed Fawzy; Patpour, Mehran; Rasheed, Awais; Mao, Long; Lagudah, Evans S.; Periyannan, Sambasivam K.; Sharon, Amir; Himmelbach, Axel; Reif, Jochen C.; Knauft, Manuela; Mascher, Martin; Stein, Nils; Chayut, Noam; Ghosh, Sreya; Perovic, Dragan; Putra, Alexander; Perera, Ana B.; Hu, Chia-Yi; Yu, Guotai; Ahmed, Hanin Ibrahim; Laquai, Konstanze D.; Rivera, Luis F.; Chen, Renjie; Wang, Yajun; Gao, Xin; Liu, Sanzhen; Raupp, W. John; Olson, Eric L.; Lee, Jong-Yeol; Chhuneja, Parveen; Kaur, Satinder; Zhang, Peng; Park, Robert F.; Ding, Yi; Liu, Deng-Cai; Li, Wanlong; Nasyrova, Firuza Y.; Dvorak, Jan; Abbasi, Mehrdad; Li, Meng; Kumar, Naveen; Meyer, Wilku B.; Boshoff, Willem H. P.; Steffenson, Brian J.; Matny, Oadi; Sharma, Parva K.; Tiwari, Vijay K.; Grewal, Surbhi; Pozniak, Curtis J.; Chawla, Harmeet Singh; Ens, Jennifer; Dunning, Luke T.; Kolmer, James A.; Lazo, Gerard R.; Xu, Steven S.; Gu, Yong Q.; Xu, Xianyang; Uauy, Cristobal; Abrouk, Michael; Bougouffa, Salim; Brar, Gurcharn S.; Wulff, Brande B. H.; Krattinger, Simon G.
作者单位:King Abdullah University of Science & Technology; University of British Columbia; King Abdullah University of Science & Technology; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Center; Egyptian Knowledge Bank (EKB); Agricultural Research Center - Egypt; Aarhus University; Quaid I Azam University; CGIAR; International Maize & Wheat Improvement Center (CIMMYT); Chinese Academy of Agricultural Sciences; Institute of Crop Sciences, CAAS; Chinese Academy of Agricultural Sciences; Institute of Crop Sciences, CAAS; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Agriculture & Food; Tel Aviv University; Leibniz Institut fur Pflanzengenetik und Kulturpflanzenforschung; German Research Foundation (DFG); German Centre for Integrative Biodiversity Research (iDiv); Martin Luther University Halle Wittenberg; Julius Kuhn-Institut; King Abdullah University of Science & Technology; Kansas State University; Kansas State University; Kansas State University; Michigan State University; National Institute of Agricultural Sciences; Rural Development Administration (RDA), Republic of Korea; Punjab Agricultural University; University of Sydney; Sichuan Agricultural University; South Dakota State University; Academy of Sciences of Republic of Tajikistan; Institute of Botany, Plant Physiology & Genetics; University of California System; University of California Davis; University of the Free State; University of Minnesota System; University of Minnesota Twin Cities; University System of Maryland; University of Maryland College Park; University of Nottingham; University of Saskatchewan; University of Sheffield; United States Department of Agriculture (USDA); United States Department of Agriculture (USDA); United States Department of Agriculture (USDA); University of Southern Queensland; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Ecology & Environment (INEE); Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Chinese Academy of Sciences; Center for Excellence in Molecular Plant Sciences, CAS; University of Manitoba; University of Alberta
摘要:Bread wheat (Triticum aestivum) is a globally dominant crop and major source of calories and proteins for the human diet. Compared with its wild ancestors, modern bread wheat shows lower genetic diversity, caused by polyploidisation, domestication and breeding bottlenecks1,2. Wild wheat relatives represent genetic reservoirs, and harbour diversity and beneficial alleles that have not been incorporated into bread wheat. Here we establish and analyse extensive genome resources for Tausch's goatg...