Nature

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• Embryonic genome instability upon DNA replication timing program emergence AI翻译
  作者：Takahashi, Saori; Kyogoku, Hirohisa; Hayakawa, Takuya; Miura, Hisashi; Oji, Asami; Kondo, Yoshiko; Takebayashi, Shin-ichiro; Kitajima, Tomoya S.; Hiratani, Ichiro
  作者单位：RIKEN; RIKEN; Kobe University; Mie University
  摘要：Faithful DNA replication is essential for genome integrity1-4. Under-replicated DNA leads to defects in chromosome segregation, which are common during embryogenesis5-8. However, the regulation of DNA replication remains poorly understood in early mammalian embryos. Here we constructed a single-cell genome-wide DNA replication atlas of pre-implantation mouse embryos and identified an abrupt replication program switch accompanied by a transient period of genomic instability. In 1- and 2-cell em...
• Plagued by mosquitoes? Try some bite-blocking fabrics AI翻译
  作者：[Anonymous]
• Scientists must step up to accelerate sustainability AI翻译
  作者：Forrester, Terrence
  作者单位：University West Indies Mona Jamaica
• First private spacewalk a success! What the SpaceX mission means for science AI翻译
  作者：Greshko, Michael
• FORGET CHATGPT: HOW TO RUN AI LOCALLY ON A LAPTOP AI翻译
  作者：Hutson, Matthew
• Three-dimensional wave breaking AI翻译
  作者：McAllister, M. L.; Draycott, S.; Calvert, R.; Davey, T.; Dias, F.; van den Bremer, T. S.
  作者单位：University of Oxford; University of Manchester; University of Edinburgh; University College Dublin; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Delft University of Technology
  摘要：Although a ubiquitous natural phenomenon, the onset and subsequent process of surface wave breaking are not fully understood. Breaking affects how steep waves become and drives air-sea exchanges1. Most seminal and state-of-the-art research on breaking is underpinned by the assumption of two-dimensionality, although ocean waves are three dimensional. We present experimental results that assess how three-dimensionality affects breaking, without putting limits on the direction of travel of the wa...
• I fire darts at whales to help track their movements AI翻译
  作者：Hedley, Esme
  作者单位：University of Groningen
• Entanglement observed in a pair of quarks AI翻译
  作者：Hentschinski, Martin
• Signatures of magnetism control by flow of angular momentum AI翻译
  作者：Chen, L.; Sun, Y.; Mankovsky, S.; Meier, T. N. G.; Kronseder, M.; Sun, C.; Orekhov, A.; Ebert, H.; Weiss, D.; Back, C. H.
  作者单位：Technical University of Munich; University of Munich; University of Munich; University of Regensburg; Technical University of Munich; University of Munich; Technical University of Munich; University of Munich; Technical University of Munich
  摘要：Exploring new strategies to manipulate the order parameter of magnetic materials by electrical means is of great importance not only for advancing our understanding of fundamental magnetism but also for unlocking potential applications. A well-established concept uses gate voltages to control magnetic properties by modulating the carrier population in a capacitor structure1-5. Here we show that, in Pt/Al/Fe/GaAs(001) multilayers, the application of an in-plane charge current in Pt leads to a s...
• Skull bones harbour immune cells that are poised to target brain tumours AI翻译
  作者：Lee, Juyeun; Lathia, Justin D.
  作者单位：Cleveland Clinic Foundation; University System of Ohio; Case Western Reserve University; Cleveland Clinic Foundation; University System of Ohio; Case Western Reserve University; Cleveland Clinic Foundation
  摘要：The human brain is usually considered to be beyond the reach of most immune cells. However, analysis of people who have brain tumours has revealed tumour-targeting T cells of the immune system in skull bones near the cancer site.