Nature

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• Structural insights into the high-affinity IgE receptor FcεRI complex AI翻译
  作者：Deng, Meijie; Du, Shuo; Hou, Handi; Xiao, Junyu
  作者单位：Peking University; Changping Laboratory; Peking University; Peking University
  摘要：Immunoglobulin E (IgE) plays a pivotal role in allergic responses(1,2). The high-affinity IgE receptor, Fc epsilon RI, found on mast cells and basophils, is central to the effector functions of IgE. Fc epsilon RI is a tetrameric complex, comprising Fc epsilon RI alpha, Fc epsilon RI beta and a homodimer of FcR gamma (originally known as Fc epsilon RI gamma), with Fc epsilon RI alpha recognizing the Fc region of IgE (Fc epsilon) and Fc epsilon RI beta-FcR gamma facilitating signal transduction(...
• Mitochondrial complex I promotes kidney cancer metastasis AI翻译
  作者：[Anonymous]
  摘要：Most kidney cancers are metabolically dysfunctional(1-4), but how this dysfunction afects cancer progression in humans is unknown. We infused C-13-labelled nutrients in over 80 patients with kidney cancer during surgical tumour resection. Labelling from [U-C-13]glucose varies across subtypes, indicating that the kidney environment alone cannot account for all tumour metabolic reprogramming. Compared with the adjacent kidney, clear cell renal cell carcinomas (ccRCCs) display suppressed labellin...
• How pain is misunderstood and ignored in women AI翻译
  作者：Nogrady, Bianca
• Micronuclear battery based on a coalescent energy transducer AI翻译
  作者：Li, Kai; Yan, Congchong; Wang, Junren; Zhu, Kun; Guo, Junjun; Zhang, Yugang; Shi, Guozheng; Yin, Yuchen; Cheng, Liwei; Sun, Liang; Wang, Yumin; Zhang, Hailong; Sun, Ying; Yuan, Jianyu; Ma, Wanli; Ji, Guoxun; Chai, Zhifang; Wang, Yaxing; Ouyang, Xiaoping; Wang, Shuao
  作者单位：Soochow University - China; Soochow University - China; Soochow University - China; Rocket Force University of Engineering; Northwest Institute of Nuclear Technology - China; Xiangtan University
  摘要：Micronuclear batteries harness energy from the radioactive decay of radioisotopes to generate electricity on a small scale, typically in the nanowatt or microwatt range(1,2). Contrary to chemical batteries, the longevity of a micronuclear battery is tied to the half-life of the used radioisotope, enabling operational lifetimes that can span several decades(3). Furthermore, the radioactive decay remains unaffected by environmental factors such as temperature, pressure and magnetic fields, makin...
• Einstein in Oxford: the untold story of an unlikely friendship AI翻译
  作者：Robinson, Andrew
  摘要：Albert Einstein's sojourns in the English city, as Nazism rose in Germany, were built on the back of a connection with a now largely forgotten don. Albert Einstein's sojourns in the English city, as Nazism rose in Germany, were built on the back of a connection with a now largely forgotten don.
• We can't recreate ancient wilderness environments - but that's not the point AI翻译
  作者：Vaughn, Justin
  作者单位：University System of Georgia; University of Georgia
  摘要：Letter to the Editor
• More measures needed to ease funding competition in China AI翻译
  作者：Sun, Wangqiang
  摘要：Letter to the Editor
• Krause corpuscles are genital vibrotactile sensors for sexual behaviours (Vol 630, pg 926, 2024) AI翻译
  作者：Qi, Lijun; Iskols, Michael; Greenberg, Rachel S.; Xiao, Jia Yin; Handler, Annie; Liberles, Stephen D.; Ginty, David D.
• Mathematics helped Britain to get in touch with continental Europe a century ago AI翻译
  作者：Dityatev, Alexander
  作者单位：Helmholtz Association; German Center for Neurodegenerative Diseases (DZNE)
  摘要：An undersea cable promises to improve Britain's relationship with Europe, and a poet's attempt at ornithology is debunked, in Nature's weekly step back in time. Snippets from Nature's past.
• Growth of brain cancer aided by lipid recycling AI翻译
  作者：Sevenich, Lisa
  作者单位：Eberhard Karls University of Tubingen; Eberhard Karls University Hospital; Eberhard Karls University of Tubingen