作者:Yang, Yang; Atkins, Constance L.; Fan, Yuanyuan; Hou, Lidan; Zhao, Jie; Gao, Junda; Wen, Yankai; Moreno, Nicolas F.; Huang, Xiangsheng; Bishehsari, Faraz; Czopik, Agnieszka K.; Colgan, Sean P.; Purnak, Tugrul; Summa, Keith C.; Cong, Yingzi; Jacobsen, Elizabeth A.; Ju, Cynthia
作者单位:University of Texas System; University of Texas Health Science Center Houston; University of Texas System; University of Texas Health Science Center Houston; University of Colorado System; University of Colorado Anschutz; Northwestern University; Feinberg School of Medicine; Mayo Clinic; Mayo Clinic Phoenix
摘要:Inflammatory bowel disease (IBD) is driven by a breakdown in immune regulation and epithelial barrier function, yet the contribution of eosinophils to this process has remained poorly defined and controversial. While eosinophils infiltrate the intestinal mucosa during both flares and remission, their role in shaping disease outcomes is unclear. Our RNA-seq analyses of colonic eosinophils isolated from dextran sulfate sodium (DSS)-treated mice revealed a significant upregulation of cyclooxygena...
作者:Hu, Xingyu; Wong, Suan Chin; Farquhar, Graham D.
作者单位:Tsinghua University; Australian National University
摘要:The intrinsic link between temperature and leaf-to-air vapor pressure difference (Delta e) complicates isolation of their individual effects on photosynthesis. Consequently, how CO2 diffusion changes under heat and high evaporative demand, particularly through mesophyll conductance (g(m)) responses, remains poorly understood. The conditions under which biochemical colimitation occurs, meaning Rubisco carboxylation and RuBP regeneration capacities match, are also unclear. To advance understandi...