31期

最新文章

• Sediment accumulation rate predicts the temporal resolution of marine fossil assemblages AI翻译
  作者：Kowalewski, Michal; Tomasovych, Adam; Nawrot, Rafal; Scarponi, Daniele; Zuschin, Martin; Albano, Paolo G.; Hua, Quan; Kaufman, Darrell S.; Kidwell, Susan M.; Ritter, Matias; Simoes, Marcello G.; Torres, Luis; Bachmann, Bettina; Berensmeier, Michaela; Dexter, Troy A.; Haselmair, Alexandra; Gallmetzer, Ivo; Pellegrini, Claudio; Schweigl, Lukas; Steger, Jan; Kosnik, Matthew A.
  作者单位：State University System of Florida; University of Florida; Slovak Academy of Sciences; Earth Science Institute, SAS; University of Vienna; University of Bologna; Stazione Zoologica Anton Dohrn; Australian Nuclear Science & Technology Organisation; University of Queensland; Northern Arizona University; University of Chicago; Universidade Federal do Rio Grande do Sul; Universidade Estadual Paulista; State University System of Florida; University of Florida; Macquarie University
  摘要：Time averaging (TA), the mixing of noncontemporaneous organisms in fossil assemblages, governs the resolution of paleontological data and determines which biological and environmental processes are recorded in the geological record. To assess variation in TA and its dependence on external drivers, we used amino acid and radiocarbon methods to individually date 7,593 specimens across 384 samples from late Quaternary marine assemblages of calcifying organisms. Bivalve mollusks dominated the data...
• Host genetic regulation of rumen 6-hydroxymelatonin reduces methane emissions in dairy cattle (vol 123, e2604454123, 2026) AI翻译
  作者：Zhang, Chenguang; Liu, Ye; Wang, Guoyan; Huang, Mengqi; Zhang, Jun; Li, Zongjun; Zhou, Linhao; Tang, Guangfu; Wu, Shengru; Deng, Lu; Yao, Junhu
• The cortical scene processing network emerges in infancy, prior to independent navigation experience AI翻译
  作者：Kamps, Frederik S.; Chen, Emily M.; Du, Haoyu; Kosakowski, Heather L.; Fuchs, Ariel; Kanwisher, Nancy; Saxe, Rebecca
  作者单位：University of Edinburgh; Massachusetts Institute of Technology (MIT); Stanford University; University of California System; University of California San Diego; University of Southern California
  摘要：Sighted people rely on vision to recognize and navigate the local environment. By adulthood, human cortex contains at least three regions that respond selectively to visual scene information, but it remains unknown when or how these regions develop. One hypothesis is that development of scene selectivity depends on passive exposure to the low-level visual statistics of scenes. Another hypothesis is that development depends on active experience using scene information to plan and guide navigati...
• MORC2 controls HIF-1α stability via an HDAC4-dependent mechanism to regulate erythropoiesis AI翻译
  作者：Tang, Yanfei; Zhang, Boqi; Xue, Tingting; Liu, Yunzhang; Li, Yun; Gu, Yuchao; Hao, Jiejie; Lu, Ling
  作者单位：Ocean University of China; Qingdao University of Science & Technology
  摘要：The hypoxia-inducible factor (HIF) signaling pathway is essential for cellular adaptation to low oxygen. Although the canonical PHD-pVHL pathway that mediates HIF-alpha degradation under normoxia is well established, alternative regulatory mechanisms remain poorly understood. Here, we identify Microrchidia family CW-type zinc-finger 2 (MORC2) as a negative regulator of HIF-alpha. In zebrafish, CRISPR/Cas9-generated morc2 mutants developed polycythemia, systemic hypoxia, and constitutive activa...
• Mitochondrial pearling is controlled by the inner membrane and mediates segregation of the luminal content and membrane scission AI翻译
  作者：Iqbal, Wasi; Zucker, Ben; Liu, Xiaoying; Wang, Ruiru; Zhu, Hongfei; Chen, Sijie; Zhou, Renjie; Liu, Xingguo; Kozlov, Michael M.; Duan, Liting
  作者单位：Chinese University of Hong Kong; Tel Aviv University; Chinese University of Hong Kong; Chinese Academy of Sciences; Chinese University of Hong Kong; Chinese University of Hong Kong
  摘要：Membrane pearling, the transformation of a smooth tubule into a chain of bead-like swellings connected by narrow membrane tethers, is a widely observed shape change. While it has been well studied for synthetic lipid and unilamellar intracellular membranes, the mechanism underlying the pearling of the peculiar double-membrane architecture of tubular mitochondria remained elusive. Here, we addressed the role of the strongly convoluted inner mitochondrial membrane (IMM) in pearling driven by str...
• Reversing vegetable biodiversity loss to diversify diets AI翻译
  作者：van Zonneveld, Maarten; Khoury, Colin K.; Herforth, Anna; Vogliano, Chris; Fowler, Cary; Gora, Sarah; Azevedo, Vania; Krishnan, Sarada; Waqainabete, Logotonu Meleisea; N'Danikou, Sognigbe; Schranz, M. Eric
  作者单位：Alliance; International Center for Tropical Agriculture - CIAT; Wageningen University & Research; CGIAR; International Potato Center (CIP); CGIAR
  摘要：Vegetables are a critical component of diets, with inadequate intake of this essential food group leading to poor dietary quality and malnutrition. Food system assessments identify insufficient production, comparatively high prices, and sociocultural barriers as key constraints to vegetable consumption. We argue that vegetable biodiversity, spanning vegetable species and their varieties, as well as their wild relative species, is a central yet underutilized lever for enhancing vegetable consum...
• Climate warming and atmospheric deposition jointly accelerate the Antarctic Peninsula atmosphere-glacier-land-ocean mercury loop AI翻译
  作者：Zhou, Chengzhen; Liu, Maodian; Zhang, Qianru; Zhang, Nikki H.; Wang, Xuejun
  作者单位：Peking University; Peking University; Peking University; Duke University; University System of Georgia; University of Georgia; Yale University
  摘要：Mercury (Hg) is a toxic pollutant of global concern that threatens ecosystem and human health. Its cycle is being jointly reshaped by anthropogenic emissions and polar warming, yet the response of the Antarctic system remains poorly constrained. Here, we reconstruct the past 200 y of Hg source-sink dynamics in the Antarctic Peninsula (AP), Antarctica's fastest-warming region with the most pronounced glacier melting, by combining geochemical and isotopic records from 16 sediment cores collected...
• Reply to Topaz and Bahl: Interpreting a post-2022 lexical shift in academic prose AI翻译
  作者：Siler, Kyle
  作者单位：University of Toronto; University Health Network Toronto
• Ubiquitination plays a key role in an insecticide resistance fitness cost AI翻译
  作者：Hu, Jinyu; Fu, Buli; Su, Qi; Guo, Xindi; Zhang, Chengjia; Tan, Qimei; Zhang, Rong; Lu, Hantang; Gong, Peipan; Liu, Shaonan; Zhou, Xuguo; Nauen, Ralf; Zhang, Youjun; Bass, Chris; Yang, Xin
  作者单位：Chinese Academy of Agricultural Sciences; Institute of Vegetables & Flowers, CAAS; Chinese Academy of Tropical Agricultural Sciences; University of Illinois System; University of Illinois Urbana-Champaign; Bayer AG
  摘要：Ubiquitination is an essential posttranslational modification in eukaryotes, which plays a fundamental role in numerous important biological functions. However, the role of ubiquitination in the evolution of adaptive traits in insects remains poorly understood. Here, we reveal the role of ubiquitination in insecticide resistance and its associated fitness cost in the whitefly pest, Bemisia tabaci. We identify the RING-type E3 ubiquitin ligase TRIM37 in B. tabaci and show its promotion of ubiqu...
• When coordination is avoidable: A monotonicity analysis of organizational tasks AI翻译
  作者：Ju, Harang
  作者单位：Johns Hopkins University
  摘要：Organizations devote substantial resources to coordination, yet which tasks actually require it for correctness remains unclear. The problem is acute in multiagent AI systems, where coordination cost is directly measurable and can exceed the cost of the work itself. Distributed systems theory provides a precise criterion: Coordination is required when a task specification is nonmonotonic, meaning that as histories grow, new information can invalidate prior conclusions. Here we show that Thomps...