2026

最新文章

• Record-high Glass coefficient in the shift current response of a ferroelectric halide perovskite AI翻译
  作者：Miki, Koma; Nakamura, Masao; Yamada, Asahi; Bosser, Gurvan; Adachi, Kiyohiro; Hashizume, Daisuke; Ogawa, Naoki; Okamoto, Satoshi; Tokura, Yoshinori; Kawasaki, Masashi
  作者单位：University of Tokyo; University of Tokyo; University of Tokyo; RIKEN; RIKEN; Tohoku University; Sumitomo Chem Co Ltd; University of Tokyo
  摘要：Ferroelectric halide perovskites provide a fertile platform for optoelectronic functions based on the bulk photovoltaic effect, where broken inversion symmetry couples with quantum geometry of wave functions. The most prominent manifestation is the shift current, second-order nonlinear photocurrent arising from change in the Berry connection during optical transitions. Here we report a gigantic shift current response in epitaxial thin films of a lead-free ferroelectric halide perovskite CsGeI3...
• Enhanced rock weathering has greater promise as a sustainable farming practice than a CO2 removal technology AI翻译
  作者：Power, Ian M.; Spence, Jonathan; Guo, Minger; Wilson, Sasha; Watmough, Shaun
  作者单位：Trent University; University of Alberta
• From molecular motors to chromosome architecture AI翻译
  作者：Zhang, Bin
  作者单位：Massachusetts Institute of Technology (MIT)
• Identification of a master regulator Msd1 that governs meiotic entry in a global basidiomycete pathogen AI翻译
  作者：Zheng, Fanglin; Cao, Yanli; Chen, Huiting; Yan, Lili; Lv, Feng; Huang, Yuan; Chen, Man; Su, Lin; Liu, Zhuozhuo; Huang, Ye; Pham, Tuyetnhu; Xu, Xinping; Lin, Xiaorong
  作者单位：Nanchang University; University System of Georgia; University of Georgia; Nanchang University; Nanchang University; University System of Georgia; University of Georgia
  摘要：Meiosis is a hallmark of sexual reproduction. Although the core meiotic machinery is evolutionarily conserved from unicellular yeasts to Metazoan, the key regulators responsible for initiating meiosis vary across species and remain largely unidentified in major eukaryotic lineages, including the major phylum Basidiomycota in the Kingdom Fungi. The basidiomycete fungus Cryptococcus neoformans is a critical pathogen listed by the World Health Organization that causes life-threatening meningoence...
• Dynamic monitoring of antibody drug conjugates targeting TROP2 or HER2 in breast cancer using circulating tumor cells AI翻译
  作者：Mishra, Avanish; Abelman, Rachel O.; Cunneely, Quinn; Putaturo, Victor; Deshpande, Akansha A.; Bell, Remy; Seider, Elizabeth M.; Xu, Katherine H.; Shan, Mythreayi; Kelly, Justin; Huang, Shih-Bo; Rieur, Olivia; Knape, Justine; Gopinathan, Kaustav A.; Kikkeri, Kruthika; Edd, Jon F.; Walsh, John; Dai, Charles S.; Ellisen, Leif W.; Ting, David T.; Nieman, Linda; Toner, Mehmet; Bardia, Aditya; Haber, Daniel A.; Maheswaran, Shyamala
  作者单位：University of California System; UCLA Jonsson Comprehensive Cancer Center; University of California Los Angeles; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Howard Hughes Medical Institute
  摘要：Antibody-drug conjugates (ADCs) target surface proteins on cancer cells, leading to internalization and delivery of a drug payload, thereby enhancing selectivity and minimizing toxicity. ADCs against TROP2 (Sacituzumab govitecan) or HER2 (T-DXd) have demonstrated efficacy in metastatic breast cancer, yet paradoxically, outside of HER2-amplified breast cancers, expression levels of these breast cancer-enriched epitopes in tumor biopsies have not been strongly correlated with clinical response. ...
• Random-with-constraints: Constructing minimal models for high-dimensional biology AI翻译
  作者：Nemenman, Ilya; Mehta, Pankaj
  作者单位：Emory University; Emory University; Emory University; Boston University; Boston University
  摘要：Biologists and physicists have a rich tradition of modeling dynamics of living systems with simple models composed of a few interacting components. Despite the remarkable success of this approach, it remains unclear how to use such finely tuned models to study complex biological systems composed of numerous heterogeneous, interacting components. One possible strategy for taming this biological complexity is to embrace the idea that many biological behaviors we observe are typical and can be mo...
• The diversity of soil parasitic protists shapes ecosystem stability worldwide AI翻译
  作者：Wang, Bing; Chen, Dima; Wang, Shuaifei; Wu, Liji; Wu, Ying; Liu, Shengen; Delgado-Baquerizo, Manuel
  作者单位：Inner Mongolia University; Fujian Agriculture & Forestry University; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Recursos Naturales y Agrobiologia de Sevilla (IRNAS)
  摘要：Soil parasitic protists influence the health of plants and soil organisms. Yet, the extent to which these interactions impact the stability of terrestrial ecosystems remains largely unquantified. Here, we utilized two independent global-scale biodiversity surveys available online to investigate the relationship between the taxonomic diversity of parasitic protists and satellite-based time series of ecosystem productivity (i.e., normalized difference vegetation index). We found that soil parasi...
• Upper mantle temperatures illuminate the Iceland hotspot track and understanding of ice-Earth interactions in Greenland (vol 122, e2504752122, 2025) AI翻译
  作者：Ajourlou, Parviz; Milne, Glenn A.; Love, Ryan; Afonso, Juan C.; Salajegheh, Farshad; Latychev, Konstantin; Kjeldsen, Kristian K.; Lepipas, Alexis; Martos, Yasmina M.; Woodroffe, Sarah A.
• Bacterial biofilms in calcium oxalate kidney stones: Where do we stand? AI翻译
  作者：Gonzalez Gonzalez, Carlos; Zorzi, Federico; Daudon, Michel; Traxer, Olivier
  作者单位：Sorbonne Universite; Assistance Publique Hopitaux Paris (APHP); Sorbonne Universite; Hopital Universitaire Tenon - APHP; Centre National de la Recherche Scientifique (CNRS); heSam Universite; CNRS - Institute for Engineering & Systems Sciences (INSIS); Conservatoire National Arts & Metiers (CNAM); Assistance Publique Hopitaux Paris (APHP); Sorbonne Universite; Hopital Universitaire Tenon - APHP
• APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans AI翻译
  作者：Amro, Elias Moris; Gkougkousis, Christos; Seebass, Joachim Guido; Telioglu, Irem; Bakr, Ali; Lorenzo, Jose Paulo; Abolhassani, Hassan; Altenhofen, Jan; Berntson, Lillemor; Ruf, Sandra; Hammarstrom, Lennart; Pan-Hammarstrom, Qiang; Imbusch, Charles D.; Papavasiliou, F. Nina
  作者单位：Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; Johannes Gutenberg University of Mainz; Helmholtz Association; German Cancer Research Center (DKFZ); Johannes Gutenberg University of Mainz; Helmholtz Association; German Cancer Research Center (DKFZ); Karolinska Institutet; Uppsala University; Helmholtz Association; German Cancer Research Center (DKFZ)
  摘要：APOBEC2 is a well-conserved member of the AID/APOBEC family of cytidine deaminases. Most members of the family catalyze the conversion of cytosine to uracil either in DNA or RNA, thereby acting as DNA mutators and/or RNA editors. APOBEC2 is the only family member that appears to be catalytically inactive. Instead, its ability to bind, but not deaminate DNA, has been co-opted into a transcription-factor-like functionality. APOBEC2 is highly expressed in skeletal muscle, where it functions to pr...