2期

最新文章

• Multifractality in spin glasses AI翻译
  作者：Baity-Jesi, Marco; Calore, Enrico; Cruz, Andres; Fernandez, Luis Antonio; Gil-Narvion, Jose Miguel; Pemartin, Isidoro Gonzalez-Adalid; Gordillo-Guerrero, Antonio; Iniguez, David; Maiorano, Andrea; Marinari, Enzo; Martin-Mayor, Victor; Moreno-Gordo, Javier; Sudupe, Antonio Munoz; Navarro, Denis; Paga, Ilaria; Parisi, Giorgio; Perez-Gaviro, Sergio; Ricci-Tersenghi, Federico; Ruiz-Lorenzo, Juan Jesus; Schifano, Sebastiano Fabio; Seoane, Beatriz; Tarancon, Alfonso; Yllanes, David
  作者单位：Swiss Federal Institutes of Technology Domain; Swiss Federal Institute of Aquatic Science & Technology (EAWAG); University of Ferrara; Istituto Nazionale di Fisica Nucleare (INFN); Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - UAM - Institut de Fisica Teorica (IFT); University of Zaragoza; Complutense University of Madrid; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - UAM - Institut de Fisica Teorica (IFT); Universidad de Extremadura; Universidad de Extremadura; University of Siena; Sapienza University Rome; Consiglio Nazionale delle Ricerche (CNR); Istituto di Nanotecnologia (NANOTEC-CNR); Istituto Nazionale di Fisica Nucleare (INFN); Universidad de Extremadura; University of Zaragoza; University of Zaragoza; Consiglio Nazionale delle Ricerche (CNR); Istituto di Nanotecnologia (NANOTEC-CNR); University of Ferrara; Istituto Nazionale di Fisica Nucleare (INFN); Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); Chan Zuckerberg Initiative (CZI)
  摘要：We unveil the multifractal behavior of Ising spin glasses in their low-temperature phase. Using the Janus II custom-built supercomputer, the spin-glass correlation function is studied locally. Dramatic fluctuations are found when pairs of sites at the same distance are compared. The scaling of these fluctuations, as the spin-glass coherence length grows with time, is characterized through the computation of the singularity spectrum and its corresponding Legendre transform. A comparatively smal...
• Sound propagation in realistic interactive 3D scenes with parameterized sources using deep neural operators AI翻译
  作者：Borrel-Jensen, Nikolas; Goswami, Somdatta; Engsig-Karup, Allan P.; Karniadakis, George Em; Jeong, Cheol-Ho
  作者单位：Technical University of Denmark; Brown University; Technical University of Denmark; Brown University
  摘要：We address the challenge of acoustic simulations in three-dimensional (3D) virtual rooms with parametric source positions, which have applications in virtual/augmented reality, game audio, and spatial computing. The wave equation can fully describe wave phenomena such as diffraction and interference. However, conventional numerical discretization methods are computationally expensive when simulating hundreds of source and receiver positions, making simulations with parametric source positions ...
• The genome of the black- footed cat: Revealing a rich natural history and urgent conservation priorities for small felids AI翻译
  作者：Yuan, Jiaqing; Kitchener, Andrew C.; Lackey, Laurie Bingaman; Sun, Ting; Jiangzuo, Qigao; Tuohetahong, Yilamujiang; Zhao, Le; Yang, Peng; Wang, Guiqiang; Huang, Chen; Wang, Jinhong; Hou, Wenhui; Liu, Yang; Chen, Wu; Mi, Da; Murphy, William J.; Li, Gang
  作者单位：Shaanxi Normal University; University of Edinburgh; Chinese Academy of Sciences; Institute of Vertebrate Paleontology & Paleoanthropology, CAS; Shaanxi University of Technology; Xi'an Jiaotong University; Texas A&M University System; Texas A&M University College Station
  摘要：Habitat degradation and loss of genetic diversity are common threats faced by almost all of today's wild cats. Big cats, such as tigers and lions, are of great concern and have received considerable conservation attention through policies and international actions. However, knowledge of and conservation actions for small wild cats are lagging considerably behind. The black- footed cat, Felis nigripes, one of the smallest felid species, is experiencing increasing threats with a rapid reduction ...
• Targeting the PHF8/YY1 axis suppresses cancer cell growth through modulation of ROS AI翻译
  作者：Wu, Xiao- Nan; Li, Jia- yuan; He, Qi; Li, Bo-qun; He, Yao-hui; Pan, Xu; Wang, Ming- yue; Sang, Rui; Ding, Jian- cheng; Gao, Xiang; Wu, Zhen; Liu, Wen
  作者单位：Xiamen University; Xiamen University; Xiamen University
  摘要：High levels of mitochondrial reactive oxygen species (mROS) are linked to cancer development, which is tightly controlled by the electron transport chain (ETC). However, the epigenetic mechanisms governing ETC gene transcription to drive mROS production and cancer cell growth remain to be fully characterized. Here, we report that protein demethylase PHF8 is overexpressed in many types of cancers, including colon and lung cancer, and is negatively correlated with ETC gene expression. While it i...
• Spatial synchrony cascades across ecosystem boundaries and up food webs via resource subsidies AI翻译
  作者：Walter, Jonathan A.; Emery, Kyle A.; Dugan, Jenifer E.; Hubbard, David M.; Bell, Tom W.; Sheppard, Lawrence W.; Karatayev, Vadim A.; Cavanaugh, Kyle C.; Reuman, Daniel C.; Castorani, Max C. N.
  作者单位：University of Virginia; University of California System; University of California Davis; University of California System; University of California Los Angeles; University of California System; University of California Santa Barbara; Woods Hole Oceanographic Institution; Marine Biological Association United Kingdom; University of Kansas; University of Kansas
  摘要：Cross-ecosystem subsidies are critical to ecosystem structure and function, especially in recipient ecosystems where they are the primary source of organic matter to the food web. Subsidies are indicative of processes connecting ecosystems and can couple ecological dynamics across system boundaries. However, the degree to which such flows can induce cross-ecosystem cascades of spatial synchrony, the tendency for system fluctuations to be correlated across locations, is not well understood. Syn...
• If psychedelics heal, how do they do it? AI翻译
  作者：Beans, Carolyn
• Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus AI翻译
  作者：Phelps, Gregory A.; Cheramie, Martin N.; Fernando, Dinesh M.; Selchow, Petra; Meyer, Christopher J.; Waidyarachchi, Samanthi L.; Dharuman, Suresh; Liu, Jiuyu; Meuli, Michael; Dal Molin, Michael; Killam, Benjamin Y.; Murphy, Patricia A.; Reeve, Stephanie M.; Wilt, Laura A.; Anderson, Shelby M.; Yang, Lei; Lee, Robin B.; Temrikar, Zaid H.; Lukka, Pradeep B.; Meibohm, Bernd; Polikanov, Yury S.; Hobbie, Sven N.; Bottger, Erik C.; Sander, Peter; Lee, Richard E.
  作者单位：St Jude Children's Research Hospital; St Jude Children's Research Hospital; University of Zurich; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; University of Tennessee System; University of Tennessee Health Science Center; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; University of Cologne
  摘要：Mycobacterium abscessus (Mab), a nontuberculous mycobacterial (NTM) species, is an emerging pathogen with high intrinsic drug resistance. Current standard- of- care therapy results in poor outcomes, demonstrating the urgent need to develop effective antimycobacterial regimens. Through synthetic modification of spectinomycin (SPC), we have identified a distinct structural subclass of N- ethylene linked aminomethyl SPCs (eAmSPCs) that are up to 64- fold more potent against Mab over the parent SP...
• Unbiased construction of constitutive relations for soft materials from experiments via rheology-informed neural networks AI翻译
  作者：Mahmoudabadbozchelou, Mohammadamin; Kamani, Krutarth M.; Rogers, Simon A.; Jamali, Safa
  作者单位：Northeastern University; University of Illinois System; University of Illinois Urbana-Champaign
  摘要：The ability to concisely describe the dynamical behavior of soft materials through closed-form constitutive relations holds the key to accelerated and informed design materials and processes. The conventional approach is to construct constitutive relations through simplifying assumptions and approximating the time-and rate dependent stress response of a complex fluid to an imposed deformation. While traditional frameworks have been foundational to our current understanding of soft materials, t...
• Thermo- photo catalytic anode process for carbonate- superstructured solid fuel cells AI翻译
  作者：Su, Hanrui; Hu, Yun Hang
  作者单位：Michigan Technological University
  摘要：Converting hydrocarbons and greenhouse gases (i.e., carbon dioxide, CO2) directly into electricity through fuel cells at intermediate temperatures (450 to 550(degrees)C) remains a significant challenge, primarily due to the sluggish activation of C-H and C=O bonds. Here, we demonstrated a unique strategy to address this issue, in which light illumination was introduced into the thermal catalytic CO2 reforming of ethane in the anode as a unique thermo-photo anode process for carbonate- superstr...
• Substitution of Met-38 to Ile in γ- synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid AI翻译
  作者：Aubrey, Liam D.; Ninkina, Natalia; Ulamec, Sabine M.; Abramycheva, Natalia Y.; Vasili, Eftychia; Devine, Oliver M.; Wilkinson, Martin; Mackinnon, Eilish; Limorenko, Galina; Walko, Martin; Muwanga, Sarah; Amadio, Leonardo; Peters, Owen M.; Illarioshkin, Sergey N.; Outeiro, Tiago F.; Ranson, Neil A.; Brockwell, David J.; Buchman, Vladimir L.; Radford, Sheena E.
  作者单位：University of Leeds; Cardiff University; Belgorod State University; Research Center of Neurology; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss School of Public Health (SSPH+); University of Leeds; University of Gottingen; UNIVERSITY GOTTINGEN HOSPITAL; Newcastle University - UK; Helmholtz Association; German Center for Neurodegenerative Diseases (DZNE)
  摘要：alpha-, beta-, and gamma-Synuclein are intrinsically disordered proteins implicated in physiological processes in the nervous system of vertebrates. alpha-synuclein (alpha Syn) is the amyloido-genic protein associated with Parkinson's disease and certain other neurodegenerative disorders. Intensive research has focused on the mechanisms that cause alpha Syn to form amyloid structures, identifying its NAC region as being necessary and sufficient for amyloid assembly. Recent work has shown that ...