2024

最新文章

• Understanding the superconductivity and charge density wave interaction through quasi-static lattice fluctuations AI翻译
  作者：Porter, Zach; Shen, Lingjia; Plumley, Rajan; Burdet, Nicolas G.; Petsch, Alexander N.; Wen, Jiajia; Drucker, Nathan C.; Peng, Cheng; Chen, Xiaoqian M.; Fluerasu, Andrei; Blackburn, Elizabeth; Coslovich, Giacomo; Hawthorn, David G.; Turner, Joshua J.
  作者单位：Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory; Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory; Carnegie Mellon University; Massachusetts Institute of Technology (MIT); Harvard University; United States Department of Energy (DOE); Brookhaven National Laboratory; Lund University; University of Waterloo
  摘要：In unconventional superconductors, coupled charge and lattice degrees of freedom can manifest in ordered phases of matter that are intertwined. In the cuprate family, fluctuating short-range charge correlations can coalesce into a longer-range charge density wave (CDW) order which is thought to intertwine with superconductivity, yet the nature of the interaction is still poorly understood. Here, by measuring subtle of seconds) through X-ray photon correlation spectroscopy, we report sensitivit...
• Interstitial telomeric sequences promote gross chromosomal rearrangement via multiple mechanisms AI翻译
  作者：Bringas, Fernando R. Rosas; Yin, Ziqing; Yao, Yue; Boudeman, Jonathan; Ollivaud, Sandra; Chang, Michael
  作者单位：University of Groningen
  摘要：Telomeric DNA sequences are difficult to replicate. Replication forks frequently pause or stall at telomeres, which can lead to telomere truncation and dysfunction. In addition to being at chromosome ends, telomere repeats are also present at internal locations within chromosomes, known as interstitial telomeric sequences (ITSs). These sequences are unstable and prone to triggering gross chromosomal rearrangements (GCRs). In this study, we quantitatively examined the effect of ITSs on the GCR ...
• Spatiotemporal bifurcation of HY5-mediated blue- light signaling regulates wood development during secondary growth AI翻译
  作者：Hwang, Hyeona; Lim, Yookyung; Oh, Myung - Min; Choi, Hyunmo; Shim, Donghwan; Song, Young Hun; Cho, Hyunwoo
  作者单位：Chungbuk National University; Chungbuk National University; National Institute of Forest Science (NIFOS), Republic of South Korea; Korea Forest Research Institute (KFRI); Chungnam National University; Seoul National University (SNU)
  摘要：Plants have evolved photoreceptors to optimize their development during primary growth, including germination, hypocotyl elongation, cotyledon opening, and root growth, allowing them to adapt to challenging light conditions. The light signaling transduction pathway during seedling establishment has been extensively studied, but little molecular evidence is available for light- regulated secondary growth, and how light regulates cambium- derived tissue production remains largely unexplored. Her...
• Genetic evidence against involvement of TRPC proteins in SOCE, ROCE, and CRAC channel function AI翻译
  作者：Susperreguy, Sebastian; Yamashita, Megumi; Choi, Chan-il; Liao, Yanhong; Burch, Lauranell H.; Blankenship, Terry L.; Hayes, Erika; Sliwa, Thomas; Zhang, Yingpei; Grenet, Dagoberto; Walker, Mitzie; Plummer, Nicholas W.; Abramowitz, Joel; Kinet, Jean Pierre; Formoso, Karina; Johnson, Brandon E.; Fleig, Andrea; Hazlehurst, Lori; Penner, Reinhold; Freichel, Marc; Flockerzi, Veit; Prakriya, Murali; Birnbaumer, Lutz
  作者单位：Pontificia Universidad Catolica Argentina; Northwestern University; Feinberg School of Medicine; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); Huazhong University of Science & Technology; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard University; Harvard Medical School; The Queen's Medical Center; University of Hawaii System; Cancer Research Center of Hawaii; University of Hawaii System; West Virginia University; Saarland University; Ruprecht Karls University Heidelberg
  摘要：Using genetically engineered mice and cell lines derived from genetically engineered mice depend obligatorily on functionally intact TRPC molecules, as SOCE monitored with have been structurally and functionally inactivated. Unexpectedly as well, we found that unaffected by ablation of all seven TRPC genes. We refer to mice and cells carrying the seven- fold disruption of TRPC genes as TRPC heptaKO mice and cells. TRPC heptaKO mice are fertile allowing the creation of a new homozygous inbred s...
• Action similarity warps visual feature space in working memory AI翻译
  作者：Trentin, Caterina; Falanga, Luigi; Jeske, Jannik; Olivers, Christian N. L.; Slagter, Heleen A.
  作者单位：Vrije Universiteit Amsterdam
  摘要：Visual working memory (VWM) retains representations of past visual information for future action. Yet to date, most studies have approached VWM as just serving perception beyond the immediate. Whether and how prospective actions shape information in VWM remains largely unknown, in part because typical experimental setups limit behavior to simple button presses. In two experiments (one preregistered), using a novel interactive VWM task, we show that the similarity of the actions that we intend ...
• Hidden in plain sight: (Re)definition of a key lepidopteran color patterning gene AI翻译
  作者：Vankuren, Nicholas W.; Kronforst, Marcus R.
  作者单位：University of Chicago
• Reply to Materić: Appropriate blanks should avoid major contamination sources in the lab AI翻译
  作者：Qian, Naixin; Stapleton, Phoebe; Yan, Beizhan; Min, Wei
  作者单位：Columbia University; Rutgers University System; Rutgers University New Brunswick; Columbia University
• Structural and hydrodynamic controls on fluid travel time distributions across fracture networks AI翻译
  作者：Davy, Philippe; Le Goc, Romain; Darcel, Caroline; Pinier, Benoit; Selroos, Jan-Olof; Le Borgne, Tanguy
  作者单位：Universite de Rennes; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Earth Sciences & Astronomy (INSU); Swedish Nuclear Fuel & Waste Management Company (SKB); Royal Institute of Technology
  摘要：Fracture networks are preferential flow paths playing a critical role in a wide range of environmental and industrial problems. Their complex multiscale structure leads to broad distributions of fluid travel times, affecting many biogeochemical processes. Yet, the relationship between the fracture network structures, their hydrodynamic properties, and the resulting anomalous transport dynamics remains unclear. We use a large database of fracture network models to investigate the factors contro...
• Salmonella virulence factors induce amino acid malabsorption in the ileum to promote ecosystem invasion of the large intestine AI翻译
  作者：Radlinski, Lauren C.; Rogers, Andrew W. L.; Bechtold, Lalita; Masson, Hugo L. P.; Nguyen, Henry; Tiffany, Connor R.; de Carvalho, Thaynara Parente; Tsolis, Renee M.; Baumler, Andreas J.
  作者单位：University of California System; University of California Davis
  摘要：The gut microbiota produces high concentrations of antimicrobial short- chain fatty acids (SCFAs) that restrict the growth of invading microorganisms. The enteric pathogen Salmonella enterica serovar (S.) Typhimurium triggers inflammation in the large intestine to ultimately reduce microbiota density and bloom, but it is unclear how the pathogen gains a foothold in the homeostatic gut when SCFA- producing commensals are abundant. Here, we show that S. Typhimurium invasion of the ileal mucosa t...
• An outcome- defining role for the triple- helical domain in regulating collagen- I assembly AI翻译
  作者：Yammine, Kathryn M.; Li, Rasia C.; Borgula, Isabella M.; Abularach, Sophia Mirda; DiChiara, Andrew S.; Raines, Ronald T.; Shoulders, Matthew D.
  作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
  摘要：Collagens are the foundational component of diverse tissues, including skin, bone, cartilage, and basement membranes, and are the most abundant protein class in animals. The fibrillar collagens are large, complex, multidomain proteins, all containing the characteristic triple helix motif. The most prevalent collagens are heterotrimeric, meaning that cells express at least two distinctive procollagen polypeptides that must assemble into specific heterotrimer compositions. The molecular mechanis...