21期

最新文章

• Experimental and theoretical evidence of universality in superfluid vortex reconnections AI翻译
  作者：Stasiak, Piotr Z.; Xing, Yiming; Alihosseini, Yousef; Barenghi, Carlo F.; Baggaley, Andrew; Guo, Wei; Galantucci, Luca; Krstulovic, Giorgio
  作者单位：Newcastle University - UK; State University System of Florida; Florida State University; State University System of Florida; Florida A&M University; Florida State University; Lancaster University; Centre National de la Recherche Scientifique (CNRS); Universite Cote d'Azur; Observatoire de la Cote d'Azur
  摘要：The minimum separation between reconnecting vortices in fluids and superfluids obeys a universal scaling law with respect to time. The prereconnection and the postreconnection prefactors of this scaling law are different, a property related to irreversibility and to energy transfer and dissipation mechanisms. In the present work, we determine the temperature dependence of these prefactors in superfluid helium from experiments and a numeric model which fully accounts for the coupled dynamics of...
• HCK regulates NLRP12-mediated PANoptosis AI翻译
  作者：Nadendla, Eswar Kumar; Alluri, Priyanshu; Sundaram, Balamurugan; Kumar, Sivakumar Prasanth; Chadchan, Sangappa B.; Sarkar, Roman; Kanneganti, Thirumala - Devi
  作者单位：St Jude Children's Research Hospital
  摘要：NOD-like receptors (NLRs) are a highly conserved family of cytosolic pattern recognition receptors that drive innate immune responses against pathogens, pathogen-associated molecular patterns, damage-associated molecular patterns, and homeostatic disruptions. Within the NLR family, NLRP12 was recently identified as a key regulator of PANoptosis, which is an innate immune, lytic cell death pathway initiated by innate immune sensors and driven by caspases and RIPKs through PANoptosome complexes....
• The white lupin CCR1 receptor- like kinase controls systemic Autoregulation of Cluster Root and Nodule Development AI翻译
  作者：Marques, Laurence; Divol, Fanchon; Boultif, Alexandra; Garcia, Fanny; Soriano, Alexandre; Maurines- Carboneill, Clea; Fernandez, Virginia; Verstraeten, Inge; Pidon, Helene; Izquierdo, Esther; Hufnagel, Barbara; Peret, Benjamin
  作者单位：Ghent University; INRAE; Institut Agro; Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS)
  摘要：Root development is tightly regulated in plants to optimize nutrient acquisition and interactions with soil microorganisms. In legumes, the Autoregulation of Nodulation (AoN) pathway systemically controls the proliferation of root nodules, which are energy-intensive organs. Mutations affecting the AoN pathway result in a hypernodulation phenotype accompanied by altered root development. However, it remains unclear whether this modification of root development is also systemic and coordinated w...
• Garaizar et al., Toward understanding lipid reorganization in RNA lipid nanoparticles in acidic environments (vol 121, e2404555121, 2024) AI翻译
  作者：Garaizar, Adiran; Diaz-Oviedo, David; Zablowsky, Nina; Rissanen, Sami; Kobberling, Johannes; Sun, Jiawei; Steiger, Christoph; Steigemann, Patrick; Mann, Florian A.; Meier, Katharina
• Induction of the ISR by AB5 subtilase cytotoxin drives type- I IFN expression in pDCs via STING activation AI翻译
  作者：Barros, Daniela; Ferreira, Beatriz H.; Garcia-Gonzalez, Paulina; Carbone, Francesco; Luka, Marine; Leite-Pinheiro, Fatima; Machado, Mariana D.; Nikolaou, Theopisti; Pilotti, Angelo; Goguet, Eliot; Antas, Paulo; Mendes, Andreia; Zhang, Lichen; Cresci, Marina; Galliot, Lou; Gigan, Julien P.; Reverendo, Marisa; Su, Bing; Narita, Miwako; Paton, Adrienne W.; Paton, James C.; Rocchi, Stephane; Rieux-Laucat, Frederic; Arguello, Rafael J.; Nal, Beatrice; Liang, Yinming; Menager, Mickael; Gatti, Evelina; Almeida, Catarina R.; Pierre, Philippe
  作者单位：Universidade de Aveiro; Institut National de la Sante et de la Recherche Medicale (Inserm); Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); Universidade de Aveiro; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Henan Medical University; Shanghai Jiao Tong University; Niigata University; Adelaide University; University of Adelaide; Universite Cote d'Azur; Institut National de la Sante et de la Recherche Medicale (Inserm); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite
  摘要：We demonstrate that exposure to the AB5 subtilase cytotoxin (SubAB) induces the unfolded protein response (UPR) in human peripheral blood mononuclear cells, concomitant with a proinflammatory response across distinct cell subsets. Notably, SubAB selectively induces type-I interferon (IFN) expression in plasmacytoid dendritic cells, acting synergistically with Toll-like receptor 7 stimulation. The induction of type-I IFN in response to SubAB relies on stimulator of interferon genes (STING) acti...
• Resonant valence bond Coulomb phase: From spins to phonons AI翻译
  作者：Castelnovo, Claudio
  作者单位：University of Cambridge
• Phase separation in mitochondrial fate and mitochondrial diseases AI翻译
  作者：Chen, Qingyi; An, Sanqi; Wang, Chuanlong; Zhou, Yanshuang; Liu, Xingguo; Ren, Wenkai
  作者单位：Guangxi Medical University; South China Agricultural University; Guangxi Medical University; Chinese Academy of Sciences; Guangzhou Medical University; Guangzhou Institute of Biomedicine & Health, CAS; Chinese Academy of Sciences; Guangzhou Institute of Biomedicine & Health, CAS; Guangzhou Medical University
  摘要：Mitochondria are central metabolic organelles that control cell fate and the development of mitochondrial diseases. Traditionally, phase separation directly regulates cell functions by driving RNA, proteins, or other molecules to concentrate into lipid droplets. Recent studies show that phase separation regulates cell functions and diseases through the regulation of subcellular organelles, particularly mitochondria. In fact, phase separation is involved in various mitochondrial activities incl...
• The GRAS protein RAM1 interacts with WRI transcription factors to regulate plant genes required for arbuscule development and function AI翻译
  作者：Paries, Michael; Hobecker, Karen; Luelmo, Sofia Hernandez; Binci, Filippo; Guercio, Angelica; Uslaender, Annika; Cardoso, Catarina; Si, Yang; Wankner, Lotta; Bashyal, Sagar; Troycke, Philip; Brueckner, Franziska; Pimprikar, Priya; Shabek, Nitzan; Gutjahr, Caroline
  作者单位：Technical University of Munich; Max Planck Society; University of California System; University of California Davis; University of Munich; University of Padua; University of Freiburg; University of California System; University of California San Diego; Salk Institute
  摘要：During arbuscular mycorrhiza (AM) symbiosis AM fungi form tree-shaped structures called arbuscules in root cortex cells of host plants. Arbuscules and their host cells are central for reciprocal nutrient exchange between the symbionts. REQUIRED FOR ARBUSCULAR MYCORRHIZATION1 (RAM1) encodes a GRAS protein crucial for transcriptionally regulating plant genes needed for arbuscule development and nutrient exchange. Similar to other GRAS proteins, RAM1 likely does not bind to DNA and how RAM1 activ...
• Food Rx: Integrating horticulture research to improve nutrition and health AI翻译
  作者：Gunter, Christopher C.; Treadwell, Danielle D.; Resende Jr, Marcio F. R.; Whitaker, Vance M.; Balmant, Kelly M.; Shelnutt, Karla P.; Borum, Peggy R.; Andrade, Juan E.; Goodrich-Schneider, Renee; Bernier, Angelina, V; Donahoo, William T.; Jaffee, Michael S.; Angle, J. Scott; Hanson, Andrew D.
  作者单位：State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida; State University System of Florida; University of Florida
  摘要：It is clear that the escalating epidemic of insulin resistance and type 2 diabetes has reached a crisis level in the United States, that overweight and obesity are drivers, and that diets and the food system have major roles. It is also clear that nutrition and medical research point to increased healthful fruit and vegetable intake as a key part of any strategy to manage the crisis. But although increasing healthful intake entails both expanding production of fruits and vegetables and improvi...
• Stability of general cognitive ability from infancy to adulthood: A combined twin and genomic investigation AI翻译
  作者：Gustavson, Daniel E.; Borriello, Giulia A.; Karhadkar, Mohini A.; Rhee, Soo Hyun; Corley, Robin P.; Rhea, Sally-Ann; DiLalla, Lisabeth F.; Wadsworth, Sally J.; Friedman, Naomi P.; Reynolds, Chandra A.
  作者单位：University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder; University System of Ohio; Kent State University; Kent State University Kent; Kent State University Salem; Southern Illinois University System; Southern Illinois University
  摘要：Measures of general cognitive ability (GCA) are highly stable from adolescence onward, particularly at the level of genetic influences. In contrast, measurement of GCA in early life (before 3 y old) is less reliable and less is known about the stability of GCA across this period, including its relation to adult GCA. Using data from the Colorado Longitudinal Twin study (N = 1,098), we examined the stability of GCA measures across 5 time-points (years 1 to 2, 3, 7, 16, and 29), including how an ...