作者：Santana, Darian J.; Anku, Juliet A. E.; Zhao, Guolei; Zarnowski, Robert; Johnson, Chad J.; Hautau, Haley; Visser, Noelle D.; Ibrahim, Ashraf S.; Andes, David; Nett, Jeniel E.; Singh, Shakti; O'Meara, Teresa R.
作者单位：University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Ghana; University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of Louisville
摘要：Candida auris is an emerging fungal pathogen responsible for health care-associated outbreaks that arise from persistent surface and skin colonization. We characterized the arsenal of adhesins used by C. auris and discovered an uncharacterized adhesin, Surface Colonization Factor (Scf1), and a conserved adhesin, Iff4109, that are essential for the colonization of inert surfaces and mammalian hosts. SCF1 is apparently specific to C. auris, and its expression mediates adhesion to inert and biolo...
作者：Thorp, H. Holden
摘要：Science is fortunate that so many authors seek to publish with us. We shoulder enormous responsibility from both our outsized influence on research across many fields and from the journal's impact on the careers of scientists who publish in our pages. Although there can be some cynicism about the role of highly selective glam journals, we understand why we are part of conversations that sometimes center around CNS (Cell, Nature, Science) periodicals. All three have considerable importance and ...
作者：Louloudis, Georgios
作者单位：University College Cork
作者：Kuhlman, Thomas E.
作者单位：University of California System; University of California Riverside
摘要：Approximately 5% of the human genome consists of short tandem repeats (STRs), sequences in which repeating units of 1 to 6 base pairs form an array of up to 100 base pairs long (1, 2). Variations in STR length are associated with, and often the causative agents of, gene expression changes present in some hereditary conditions, for example, Huntington's disease, autism, and schizophrenia (3-5). However, the mechanisms through which STRs exert their effects on gene expression remain poorly under...
作者：Buckley, Ralf
作者单位：Griffith University; Griffith University - Gold Coast Campus
