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作者：Dubash, Navroz K.
作者单位：National University of Singapore
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作者：Avila-Arcos, Maria C.; Raghavan, Maanasa; Schlebusch, Carina
作者单位：Universidad Nacional Autonoma de Mexico; University of Chicago; Uppsala University; University of Johannesburg; SciLifeLab
摘要：Ancient DNA (aDNA) has added a wealth of information about our species' history, including insights on genetic origins, migrations and gene flow, genetic admixture, and health and disease. Much early work has focused on continental-level questions, leaving many regional questions, especially those relevant to the Global South, comparatively underexplored. A few success stories of aDNA studies from smaller laboratories involve more local aspects of human histories and health in the Americas, Af...
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作者：Bezerra, Paulo
作者单位：Universidade Federal Rural do Semi-Arido (UFERSA)
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作者：Dalen, Love; Heintzman, Peter D.; Kapp, Joshua D.
作者单位：Swedish Museum of Natural History; Stockholm University; Swedish Museum of Natural History; Stockholm University; University of California System; University of California Santa Cruz; University of California System; University of California Santa Cruz; University of California System; University of California Santa Cruz; Howard Hughes Medical Institute
摘要：Although most ancient DNA studies have focused on the last 50,000 years, paleogenomic approaches can now reach into the early Pleistocene, an epoch of repeated environmental changes that shaped present-day biodiversity. Emerging deep-time genomic transects, including from DNA preserved in sediments, will enable inference of adaptive evolution, discovery of unrecognized species, and exploration of how glaciations, volcanism, and paleomagnetic reversals shaped demography and community compositio...
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作者：Normile, Dennis
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作者：Servick, Kelly
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作者：Lebrette, Hugo; Srinivas, Vivek; John, Juliane; Aurelius, Oskar; Kumar, Rohit; Lundin, Daniel; Brewster, Aaron S.; Bhowmick, Asmit; Sirohiwal, Abhishek; Kim, In-Sik; Gul, Sheraz; Pham, Cindy; Sutherlin, Kyle D.; Simon, Philipp; Butryn, Agata; Aller, Pierre; Orville, Allen M.; Fuller, Franklin D.; Alonso-Mori, Roberto; Batyuk, Alexander; Sauter, Nicholas K.; Yachandra, Vittal K.; Yano, Junko; Kaila, Ville R. I.; Sjoberg, Britt-Marie; Kern, Jan; Roos, Katarina; Hogbom, Martin
作者单位：Stockholm University; Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Centre National de la Recherche Scientifique (CNRS); Lund University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Diamond Light Source; Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory; Uppsala University; Francis Crick Institute
摘要：Aerobic ribonucleotide reductases (RNRs) initiate synthesis of DNA building blocks by generating a free radical within the R2 subunit; the radical is subsequently shuttled to the catalytic R1 subunit through proton-coupled electron transfer (PCET). We present a high-resolution room temperature structure of the class Ie R2 protein radical captured by x-ray free electron laser serial femtosecond crystallography. The structure reveals conformational reorganization to shield the radical and connec...
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作者：Zhang, Rui; Wang, Yong; Gaspard, Pierre; Kruse, Norbert
作者单位：Washington State University; United States Department of Energy (DOE); Pacific Northwest National Laboratory; Universite Libre de Bruxelles; Universite Libre de Bruxelles
摘要：The mechanistic steps that underlie the formation of higher hydrocarbons in catalytic carbon monoxide (CO) hydrogenation at atmospheric pressure over cobalt-based catalysts (Fischer-Tropsch synthesis) have remained poorly understood. We reveal nonisothermal rate-and-selectivity oscillations that are self-sustained over extended periods of time (>24 hours) for a cobalt/cerium oxide catalyst with an atomic ratio of cobalt to cerium of 2:1 (Co2Ce1) at 220 degrees C and equal partial pressures of ...
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作者：Capson, Todd L.
作者单位：Universite Paris Cite
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作者：Servick, Kelly
