-
作者：Sulis, Daniel B.; Jiang, Xiao; Yang, Chenmin; Marques, Barbara M.; Matthews, Megan L.; Miller, Zachary; Lan, Kai; Cofre-Vega, Carlos; Liu, Baoguang; Sun, Runkun; Sederoff, Henry; Bing, Ryan G.; Sun, Xiaoyan; Williams, Cranos M.; Jameel, Hasan; Phillips, Richard; Chang, Hou-min; Peszlen, Ilona; Huang, Yung-Yun; Li, Wei; Kelly, Robert M.; Sederoff, Ronald R.; Chiang, Vincent L.; Barrangou, Rodolphe; Wang, Jack P.
作者单位：North Carolina State University; North Carolina State University; North Carolina State University; North Carolina State University; University of Illinois System; University of Illinois Urbana-Champaign; Beihua University; North Carolina State University; North Carolina State University; North Carolina State University; Northeast Forestry University - China; North Carolina State University
摘要：The domestication of forest trees for a more sustainable fiber bioeconomy has long been hindered by the complexity and plasticity of lignin, a biopolymer in wood that is recalcitrant to chemical and enzymatic degradation. Here, we show that multiplex CRISPR editing enables precise woody feedstock design for combinatorial improvement of lignin composition and wood properties. By assessing every possible combination of 69,123 multigenic editing strategies for 21 lignin biosynthesis genes, we ded...
-
作者：Zheng, Yun; Zhai, Chonghao; Liu, Dajian; Mao, Jun; Chen, Xiaojiong; Dai, Tianxiang; Huang, Jieshan; Bao, Jueming; Fu, Zhaorong; Tong, Yeyu; Zhou, Xuetong; Yang, Yan; Tang, Bo; Li, Zhihua; Li, Yan; Gong, Qihuang; Tsang, Hon Ki; Dai, Daoxin; Wang, Jianwei
作者单位：Peking University; Zhejiang University; Zhejiang University; Hong Kong University of Science & Technology (Guangzhou); Chinese University of Hong Kong; Chinese Academy of Sciences; Institute of Microelectronics, CAS; Peking University; Peking University; Tsinghua University; Collaborative Innovation Center of Quantum Matter; Peking University; Hefei National Laboratory
摘要：Quantum networks provide the framework for quantum communication, clock synchronization, distributed quantum computing, and sensing. Implementing large-scale and practical quantum networks relies on the development of scalable architecture and integrated hardware that can coherently interconnect many remote quantum nodes by sharing multidimensional entanglement through complex-medium quantum channels. We demonstrate a multichip multidimensional quantum entanglement network based on mass-manufa...
-
作者：Funk, Michael
-
作者：Sen, Ananya
作者单位：University of Illinois System; University of Illinois Urbana-Champaign
-
作者：DeCamp, Matthew; Lindvall, Charlotta
作者单位：University of Colorado System; University of Colorado Anschutz Medical Campus; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard Medical School
摘要：Artificial intelligence (AI) shows promise for improving basic and translational science, medicine, and public health, but its success is not guaranteed. Numerous examples have arisen of racial, ethnic, gender, disability, and other biases in AI applications to health care. In ethics, bias generally refers to any systematic, unfair favoring of people in terms of how they are treated or the outcomes they experience. Consensus has emerged among scientists, ethicists, and policy-makers that minim...
-
作者：McKnight, Steven; Spradling, Allan
作者单位：University of Texas System; University of Texas Southwestern Medical Center; Carnegie Institution for Science
-
作者：Brainard, Jeffrey
-
作者：Mitchell, Melanie
作者单位：The Santa Fe Institute
-
作者：Appenzeller, Tim
-
作者：Jensen, Olaf P.
作者单位：University of Wisconsin System; University of Wisconsin Madison
