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作者：Veugelers, Reinhilde; Harhoff, Dietmar
作者单位：KU Leuven; Peterson Institute for International Economics
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作者：Wong, Felix; de la Fuente-nunez, Cesar; Collins, James J.
作者单位：Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; Harvard University
摘要：Despite advances in molecular biology, genetics, computation, and medicinal chemistry, infectious disease remains an ominous threat to public health. Addressing the challenges posed by pathogen outbreaks, pandemics, and antimicrobial resistance will require concerted interdisciplinary efforts. In conjunction with systems and synthetic biology, artificial intelligence (AI) is now leading to rapid progress, expanding anti-infective drug discovery, enhancing our understanding of infection biology...
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作者：Lazar, Seth; Nelson, Alondra
作者单位：Australian National University; Institute for Advanced Study - USA
摘要：Rapid, widespread adoption of the latest large language models has sparked both excitement and concern about advanced artificial intelligence (AI). In response, many are looking to the field of AI safety for answers. Major AI companies are purportedly investing heavily in this young research program, even as they cut trust and safety teams addressing harms from current systems. Governments are taking notice too. The United Kingdom just invested 100 pound million in a new Foundation Model Taskf...
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作者：[Anonymous]
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作者：Mariotti, Silvia; Koehnen, Eike; Scheler, Florian; Sveinbjoernsson, Kari; Zimmermann, Lea; Piot, Manuel; Yang, Fengjiu; Li, Bor; Warby, Jonathan; Musiienko, Artem; Menzel, Dorothee; Lang, Felix; Kessler, Sebastian; Levine, Igal; Mantione, Daniele; Al-Ashouri, Amran; Haertel, Marlene S.; Xu, Ke; Cruz, Alexandros; Kurpiers, Jona; Wagner, Philipp; Koebler, Hans; Li, Jinzhao; Magomedov, Artiom; Mecerreyes, David; Unger, Eva; Abate, Antonio; Stolterfoht, Martin; Stannowski, Bernd; Schlatmann, Rutger; Korte, Lars; Albrecht, Steve
作者单位：Helmholtz Association; Helmholtz-Zentrum fuer Materialien und Energie GmbH (HZB); Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of Potsdam; University of Basque Country; POLYMAT; Basque Foundation for Science; Kaunas University of Technology; Technical University of Berlin; Okinawa Institute of Science & Technology Graduate University
摘要：Improved stability and efficiency of two-terminal monolithic perovskite-silicon tandem solar cells will require reductions in recombination losses. By combining a triple-halide perovskite (1.68 electron volt bandgap) with a piperazinium iodide interfacial modification, we improved the band alignment, reduced nonradiative recombination losses, and enhanced charge extraction at the electron-selective contact. Solar cells showed open-circuit voltages of up to 1.28 volts in p-i-n single junctions ...
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作者：Chabin, Michele
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作者：Hartke, Thomas; Oreg, Botond; Turnbaugh, Carter; Jia, Ningyuan; Zwierlein, Martin
作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要：The Hubbard model of attractively interacting fermions provides a paradigmatic setting for fermion pairing. It features a crossover between Bose-Einstein condensation of tightly bound pairs and Bardeen-Cooper-Schrieffer superfluidity of long-range Cooper pairs, and a pseudo-gap region where pairs form above the superfluid critical temperature. We directly observe the nonlocal nature of fermion pairing in a Hubbard lattice gas, using spin- and density-resolved imaging of similar to 1000 fermion...
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作者：Budolfson, Mark; Fischer, Bob; Scovronick, Noah
作者单位：Rutgers University System; Rutgers University New Brunswick; Rutgers University System; Rutgers University New Brunswick; University of Texas System; University of Texas Austin; Texas State University System; Texas State University San Marcos; Emory University; Rollins School Public Health
摘要：New methods are emerging to quantify human and animal welfare on a common scale, creating new tools for policy There is growing international consensus that animal welfare is a crucial consideration in policy analysis, affecting domains ranging from food systems to biomedical research. Concern for animal welfare also features in many government regulations, certification programs, and institutional ethics codes across the globe and is central to many philanthropic and values-based investment d...
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作者：Thorp, H. Holden
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作者：Pownall, Mark E.; Miao, Liyun; Vejnar, Charles E.; M'Saad, Ons; Sherrard, Alice; Frederick, Megan A.; Benitez, Maria D. J.; Boswell, Curtis W.; Zaret, Kenneth S.; Bewersdorf, Joerg; Giraldez, Antonio J.
作者单位：Yale University; Yale University; Yale University; University of Pennsylvania; Yale University; Yale University; Yale University; Yale University; Yale University; Yale New Haven Hospital
摘要：Nanoscale chromatin organization regulates gene expression. Although chromatin is notably reprogrammed during zygotic genome activation (ZGA), the organization of chromatin regulatory factors during this universal process remains unclear. In this work, we developed chromatin expansion microscopy (ChromExM) to visualize chromatin, transcription, and transcription factors in vivo. ChromExM of embryos during ZGA revealed how the pioneer factor Nanog interacts with nucleosomes and RNA polymerase I...
