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作者:Myhre, Gunnar; Hodnebrog, Oivind; Loeb, Norman; Forster, Piers M.
作者单位:National Aeronautics & Space Administration (NASA); NASA Langley Research Center; University of Leeds
摘要:Climate forcings by greenhouse gases and aerosols cause an imbalance at the top of the atmosphere between the net incoming solar radiation and outgoing longwave radiation from Earth. This Earth energy imbalance has strengthened over the period 2001 to 2023 with satellite data. Here, we show that low climate sensitivity models fail to reproduce the trend in Earth energy imbalance, particularly in the individual longwave and shortwave contributions to the imbalance trend. The inability to produc...
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作者:Weingarten-Gabbay, Shira; Bauer, Matthew R.; Stanton, Alexandra C.; Yu, Yingpu; Freije, Catherine A.; Welch, Nicole L.; Boehm, Chloe K.; Klaeger, Susan; Verzani, Eva K.; Lopez, Daniel; Hensley, Lisa E.; Clauser, Karl R.; Carr, Steven A.; Abelin, Jennifer G.; Rice, Charles M.; Sabeti, Pardis C.
作者单位:Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Rockefeller University; Harvard University; Harvard Medical School; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Instituto de Salud Carlos III; Centro Nacional de Microbiologia (CNM); United States Department of Agriculture (USDA); Harvard University; Harvard T.H. Chan School of Public Health; Harvard University; Harvard Medical School; Harvard University
摘要:Defining viral proteomes is crucial to understanding viral life cycles and immune recognition but the landscape of translated regions remains unknown for most viruses. We have developed massively parallel ribosome profiling (MPRP) to determine open reading frames (ORFs) across tens of thousands of designed oligonucleotides. MPRP identified 4208 unannotated ORFs in 679 human-associated viral genomes. We found viral peptides originating from detected noncanonical ORFs presented on class-I human ...
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作者:Yeaman, Sam
作者单位:University of Calgary
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作者:Cogalniceanu, Dan; Szekely, Diana
作者单位:Ovidius University; Universidad Tecnica Particular de Loja
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作者:Huang, Yan Yan Shery; Ju, Lining Arnold
作者单位:University of Cambridge; University of Cambridge; University of Sydney; University of Sydney; Heart Research Institute
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作者:Boon, Sarah
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作者:Parrish, Katherine A.; Salij, Andrew; Kamp, Kendall R.; Smith, Evan; Utama, M. Iqbal Bakti; Bergsten, Anders J.; Czerwinski, Rachel; Smith, Mackinsey A.; Hersam, Mark C.; Poeppelmeier, Kenneth R.; Goldsmith, Randall H.; Tempelaar, Roel
作者单位:University of Wisconsin System; University of Wisconsin Madison; Northwestern University; United States Department of Energy (DOE); Los Alamos National Laboratory; Northwestern University
摘要:Crystalline solids are governed by universal structure-property relationships derived from their crystal symmetry, leading to paradigmatic rules on what properties they can and cannot exhibit. A long-held structure-property relationship is that centrosymmetric crystals cannot differentially absorb circularly polarized light. In this study, we demonstrate the design, synthesis, and characterization of the centrosymmetric material Li2Co3(SeO3)(4), which violates this relationship not by defying ...
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作者:Du, Zhicheng; Liu, Changyue; Xie, Zhaotian; Luo, Hui-Yan; Zhang, Wentao; He, Xin
作者单位:Tsinghua University; Tsinghua University; Tsinghua Shenzhen International Graduate School; Sun Yat Sen University; State Key Lab Oncology South China
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作者:O'Grady, Cathleen
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作者:Stubbusch, Astrid K. M.; Peaudecerf, Francois J.; Lee, Kang Soo; Paoli, Lucas; Schwartzman, Julia; Stocker, Roman; Basler, Marek; Schubert, Olga T.; Ackermann, Martin; Magnabosco, Cara; D'Souza, Glen G.
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute of Aquatic Science & Technology (EAWAG); Swiss Federal Institutes of Technology Domain; ETH Zurich; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Physics (INP); Universite de Rennes; Swiss Federal Institutes of Technology Domain; ETH Zurich; Ulsan National Institute of Science & Technology (UNIST); Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Institute of Bioinformatics; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss School of Public Health (SSPH+); Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of Southern California; University of Basel; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe
摘要:In natural habitats, nutrient availability limits bacterial growth. We discovered that bacteria can overcome this limitation by acquiring nutrients by lysing neighboring cells through contact-dependent antagonism. Using single-cell live imaging and isotopic markers, we found that during starvation, the type VI secretion system (T6SS) lysed neighboring cells and thus provided nutrients from lysing cells for growth. Genomic adaptations in antagonists, characterized by a reduced metabolic gene re...