6765期

最新文章

• Fire heat affects the impacts of wildfires on air pollution in the United States AI翻译
  作者：Ma, Qihan; Wei, Linyi; Wang, Yong; Zhang, Guang J.; Zhou, Xinlin; Wang, Bin
  作者单位：Fudan University; Tsinghua University; Chinese Academy of Sciences; Institute of Earth Environment, CAS; University of California System; University of California San Diego; Scripps Institution of Oceanography; Chinese Academy of Sciences; Institute of Atmospheric Physics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
  摘要：Conventional wisdom suggests that wildfires in the western United States (WUS) degrade air quality nationwide as a result of aerosol emissions and eastward transport. However, we found that heat produced by wildfires, a commonly neglected effect, can reduce fine particle concentrations (PM2.5) in the eastern United States (EUS) by an amount comparable to the increases in the WUS during the fire season. This phenomenon arises from fire heat-induced convection in the WUS and subsequent downstrea...
• Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex AI翻译
  作者：Dietrich, Melanie H.; Chmielewski, Jill; Chan, Li-Jin; Tan, Li Lynn; Adair, Amy; Lyons, Frankie M. T.; Gabriela, Mikha; Lopaticki, Sash; Dite, Toby A.; Dagley, Laura F.; Pazzagli, Lucia; Gupta, Priya; Kamil, Mohd; Vaughan, Ashley M.; Rojrung, Rattanaporn; Abraham, Anju; Mazhari, Ramin; Longley, Rhea J.; Zeglinski, Kathleen; Gouil, Quentin; Mueller, Ivo; Fabb, Stewart A.; Shandre-Mugan, Rekha; Pouton, Colin W.; Glukhova, Alisa; Shakeel, Shabih; Tham, Wai-Hong
  作者单位：Walter & Eliza Hall Institute; University of Melbourne; University of Melbourne; Peter Doherty Institute; Seattle Children's Hospital; University of Washington; University of Washington Seattle; Ehime University; Mahidol University; La Trobe University; Olivia Newton-John Cancer Research Institute; La Trobe University; Shanghai Jiao Tong University; Monash University; University of Melbourne; Monash University; Monash University; Australian National University
  摘要：Malaria parasite fertilization occurs in the midgut of a female Anopheles mosquito. Blocking fertilization within the mosquito can prevent malaria transmission. Plasmodium falciparum Pfs230 and Pfs48/45 proteins are critical for male fertility and transmission of the malaria parasite. They form a core fertilization complex, but it is unknown how they interact. We determined a cryo-electron microscopy structure of the endogenous Pfs230-Pfs48/45 complex showing that Pfs48/45 interacts with Pfs23...
• Drop-printing with dynamic stress release for conformal wrap of bioelectronic interfaces AI翻译
  作者：Li, An; Zhou, Wenjianlong; Li, Huizeng; Fang, Wei; Luo, Yifei; Li, Zheng; Zhang, Qingrong; Liu, Quan; Xu, Qin; Xue, Luanluan; Li, Kaixuan; Yuan, Renxuan; Liu, Wanling; Jia, Wang; Chen, Xiaodong; Song, Yanlin
  作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Chemistry, CAS; Capital Medical University; Tianjin University; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Materials Research & Engineering (IMRE); Army Medical University; Army Medical University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Nanyang Technological University
  摘要：Bioelectronic interfaces demonstrate promising applications in health monitoring, medical treatment, and augmented reality. However, conformally wrapping these film devices onto three-dimensional surfaces often leads to stress-induced damage. We propose a drop-printing strategy that enables damage-free film transfer using a droplet. The droplet acts as a lubricating layer between the film and the target surface, facilitating local sliding during shape-adaptive deformation. This mechanism preve...
• Fragmentation increased in over half of global forests from 2000 to 2020 AI翻译
  作者：Zou, Yibiao; Crowther, Thomas W.; Smith, Gabriel Reuben; Ma, Haozhi; Mo, Lidong; Bialic-Murphy, Lalasia; Potapov, Peter; Gawecka, Klementyna A.; Xu, Chi; Negret, Pablo J.; Lauber, Thomas; Wu, Zhaofei; Rebindaine, Dominic; Zohner, Constantin M.
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; Nankai University; University System of Maryland; University of Maryland College Park; University of Zurich; UK Centre for Ecology & Hydrology (UKCEH); Nanjing University; University of Bern; Western Sydney University; Beijing Normal University
  摘要：Habitat fragmentation, in which contiguous forests are broken into smaller, isolated patches, threatens biodiversity by disrupting species movement, shrinking populations, and altering ecosystem dynamics. Past assessments suggested declining global fragmentation, but they relied on structure-based metrics that overlook ecological connectivity. We analyzed global forest fragmentation from 2000 to 2020 using complementary metrics that captured patch connectivity, aggregation, and structure. Conn...
• Illusions of AI consciousness AI翻译
  作者：Bengio, Yoshua; Elmoznino, Eric
  作者单位：Universite de Montreal; Mila Quebec Artificial Intelligence Institute
• Gene flow stops sooner in plants than in animals AI翻译
  作者：Brandvain, Yaniv
  作者单位：University of Minnesota System; University of Minnesota Twin Cities
• In Other Journals AI翻译
  作者：Ray, L. Bryan; Vignieri, Sacha; Smith, Jesse; Seale, Madeleine; Wible, Brad; Jiang, Di; Stajic, Jelena
• Genomic signatures indicate biodiversity loss in an endemic island ant fauna AI翻译
  作者：Liu, Cong; Sarnat, Eli; Tan, Jo Ann; Janicki, Julia; Deyrup, John; Ogasawara, Masako; Grau, Miquel L.; Qiu, Lijun; Hita Garcia, Francisco; Fischer, Georg; Caginitoba, Akanisi; Narula, Nitish; Darwell, Clive T.; Kubota, Yasuhiro; Pierce, Naomi E.; Mikheyev, Alexander S.; Economo, Evan P.
  作者单位：Okinawa Institute of Science & Technology Graduate University; University of the Ryukyus; Harvard University; Okinawa Institute of Science & Technology Graduate University; Leibniz Institut fur Evolutions und Biodiversitatsforschung; Australian National University; University System of Maryland; University of Maryland College Park
  摘要：Insect populations have declined worldwide, but the extent and drivers of these declines are debated. Most studies rely on field surveys performed in the past century, leaving gaps in our understanding of longer-term trends. Using a community genomics approach, we estimated community assembly over millions of years and more recent demographic trends of ant species in the Fijian archipelago. We found that 79% of endemic species are in decline, starting after the arrival of humans approximately ...
• Science Under Siege AI翻译
  作者：Ranney, Megan L.
  作者单位：Yale University
• E. coli transcription factors regulate promoter activity by a universal, homeostatic mechanism AI翻译
  作者：Parisutham, Vinuselvi; Guharajan, Sunil; Lian, Melina; Ali, Md Zulfikar; Rogers, Hannah; Joyce, Shannon; Noto Guillen, Mariana; Brewster, Robert C.
  作者单位：University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; University of Southern California
  摘要：Transcription factors (TFs) may activate or repress gene expression through an interplay of different mechanisms, including RNA polymerase (RNAP) recruitment, exclusion, and initiation. However, depending on the regulated promoter identity, TF function can vary, and the principles underlying this context dependence remain unclear. We demonstrate an inverse scaling relationship between the promoter's basal activity and its regulation by a given TF. Specifically, activation is weaker and repress...