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作者:Farrell, Jordan S.; Soltesz, Ivan
作者单位:Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Stanford University; Stanford University
摘要:Traditional views of hippocampal function are largely based on the canonical flow of information from the entorhinal cortex through the trisynaptic loop-comprising the dentate gyrus and cornu ammonis regions CA3 and CA1-and back to cortex, where the hippocampus plays an important role in transforming relevant information into a usable storage system. This classic circuit has inspired current thinking on hippocampal functions related to learning, memory, and spatial navigation, but the potentia...
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作者:Ram, Natalie; Prince, Anya E. R.; Roberts, Jessica L.; Fox, Dov; Spector-Bagdady, Kayte
作者单位:University System of Maryland; University of Maryland Baltimore; Johns Hopkins University; University of Iowa; Emory University; University of San Diego; University of Michigan System; University of Michigan
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作者:Cohen, Jon
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作者:Jacobs, Phie
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作者:Brandvain, Yaniv
作者单位:University of Minnesota System; University of Minnesota Twin Cities
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作者:Ray, L. Bryan; Vignieri, Sacha; Smith, Jesse; Seale, Madeleine; Wible, Brad; Jiang, Di; Stajic, Jelena
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作者:Kroeze, Ronen M.; Marsh, Brendan P.; Atri Schuller, David; Hunt, Henry S.; Bourzutschky, Alexander N.; Winer, Michael; Gopalakrishnan, Sarang; Keeling, Jonathan; Lev, Benjamin L.
作者单位:Stanford University; Stanford University; Stanford University; University System of Maryland; University of Maryland College Park; Princeton University; University of St Andrews
摘要:Spin glasses are quintessential examples of complex matter. Although their ordering lacks complete theoretical understanding, abstract models of spin glasses inform problems in other fields, such as combinatorial optimization and artificial intelligence-where they form a mathematical basis for neural network computing. We demonstrate the ability to realize a spin glass of a distinct driven-dissipative and vector form. By microscopically visualizing its glassy spin states, the technique allows ...
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作者:Lu, Kuan-Jen; Hsu, Chia-Wei; Jane, Wann-Neng; Peng, Mien-Hao; Chou, Ya-Wen; Huang, Pin-Hsuan; Yeh, Kuo-Chen; Wu, Shu-Hsing; Liao, James C.
作者单位:Academia Sinica - Taiwan; Academia Sinica - Taiwan; Academia Sinica - Taiwan
摘要:Carbon fixation through the Calvin-Benson-Bassham (CBB) cycle accounts for the majority of carbon dioxide (CO2) uptake from the atmosphere. The CBB cycle generates C3 carbohydrates but is inefficient at producing acetyl-coenzyme A (CoA) (C2), which is the universal precursor for synthesizing lipids. In this work, we introduced in Arabidopsis thaliana a new-to-nature CO2 fixing cycle, malyl-CoA-glycerate (McG) cycle, which together with the CBB cycle forms a dual-cycle CO2 fixation system. This...
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作者:Shen, Lili; Ren, Fei; Wang, Yin-Chu; Li, Zhenhua; Zheng, Mengyuan; Li, Xiaoyi; Fan, Wenzheng; Yang, Yanyan; Sang, Min; Liu, Cheng; Han, Guangye; Qin, Song; Fan, Jianhua; Tian, Lijin; Kuang, Tingyun; Shen, Jian-Ren; Wang, Wenda
作者单位:Chinese Academy of Sciences; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Yantai Institute of Coastal Zone Research, CAS; Shihezi University; Okayama University
摘要:Photosystem I (PSI) is a pigment-protein complex, which converts light energy into chemical energy in photosynthesis. Among photosynthetic organisms, PSI-LHC (light-harvesting complex) structures exhibit substantial differences in their sizes, reflecting adaptation to different light environments. Here we report the structure of a PSI-fucoxanthin chlorophyll a/c binding protein (FCPI) supercomplex from the coccolithophore Emiliania huxleyi (Eh) at 2.79-angstrom resolution by cryo-electron micr...
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作者:Leshner, Alan I.; Helman, Alex M.
作者单位:National Academies of Sciences, Engineering & Medicine