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作者:Brasier, Noe; Wang, Joseph; Gao, Wei; Sempionatto, Juliane R.; Dincer, Can; Ates, H. Ceren; Guder, Firat; Olenik, Selin; Schauwecker, Ivo; Schaffarczyk, Dietmar; Vayena, Effy; Ritz, Nicole; Weisser, Maja; Mtenga, Sally; Ghaffari, Roozbeh; Rogers, John A.; Goldhahn, Joerg
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; University of California System; University of California San Diego; California Institute of Technology; University of Freiburg; University of Freiburg; Technical University of Munich; Imperial College London; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Basel; University of Basel; Lucerne Cantonal Hospital; Ifakara Health Institute; University of Basel; Swiss Tropical & Public Health Institute; University of Basel; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Feinberg School of Medicine
摘要:Wearable sensors are a recent paradigm in healthcare, enabling continuous, decentralized, and non- or minimally invasive monitoring of health and disease. Continuous measurements yield information-rich time series of physiological data that are holistic and clinically meaningful. Although most wearable sensors were initially restricted to biophysical measurements, the next generation of wearable devices is now emerging that enable biochemical monitoring of both small and large molecules in a v...
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作者:Tran, Tuan M.
作者单位:Indiana University System; Indiana University Indianapolis
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作者:Gibney, Elizabeth
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作者:Melchor, Stephanie
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作者:Nikas, Alexandros; Frilingou, Natasha; Al Khourdajie, Alaa; Gambhir, Ajay
作者单位:National Technical University of Athens; Imperial College London
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作者:Shin, Won Dong; Phan, Hoang-Vu; Daley, Monica A.; Ijspeert, Auke J.; Floreano, Dario
作者单位:Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of California System; University of California Irvine; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要:Most birds can navigate seamlessly between aerial and terrestrial environments. Whereas the forelimbs evolved into wings primarily for flight, the hindlimbs serve diverse functions such as walking, hopping and leaping, and jumping take-off for transitions into flight1. These capabilities have inspired engineers to aim for similar multimodality in aerial robots, expanding their range of applications across diverse environments. However, challenges remain in reproducing multimodal locomotion, ac...
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作者:Sango, Junya; Carcamo, Saul; Sirenko, Maria; Maiti, Abhishek; Mansour, Hager; Ulukaya, Gulay; Tomalin, Lewis E.; Cruz-Rodriguez, Nataly; Wang, Tiansu; Olszewska, Malgorzata; Olivier, Emmanuel; Jaud, Manon; Nadorp, Bettina; Kroger, Benjamin; Hu, Feng; Silverman, Lewis; Chung, Stephen S.; Wagenblast, Elvin; Chaligne, Ronan; Eisfeld, Ann-Kathrin; Demircioglu, Deniz; Landau, Dan A.; Lito, Piro; Papaemmanuil, Elli; Dinardo, Courtney D.; Hasson, Dan; Konopleva, Marina; Papapetrou, Eirini P.
作者单位:Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; University of Texas System; UTMD Anderson Cancer Center; New York University; New York University; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; Memorial Sloan Kettering Cancer Center; University of Texas System; University of Texas Southwestern Medical Center; Cornell University; Weill Cornell Medicine; University System of Ohio; Ohio State University; James Cancer Hospital & Solove Research Institute; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University
摘要:Cancer driver mutations often show distinct temporal acquisition patterns, but the biological basis for this, if any, remains unknown. RAS mutations occur invariably late in the course of acute myeloid leukaemia, upon progression or relapsed/refractory disease1, 2, 3, 4, 5-6. Here, by using human leukaemogenesis models, we first show that RAS mutations are obligatory late events that need to succeed earlier cooperating mutations. We provide the mechanistic explanation for this in a requirement...
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作者:Yao, Christina W.
作者单位:University of South Carolina System; University of South Carolina Columbia
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作者:Robin, Marc; Mouloungui, Elodie; Castillo Dali, Gabriel; Wang, Yan; Saffar, Jean-Louis; Pavon-Djavid, Graciela; Divoux, Thibaut; Manneville, Sebastien; Behr, Luc; Cardi, Delphine; Choudat, Laurence; Giraud-Guille, Marie-Madeleine; Meddahi-Pelle, Anne; Baudimont, Fannie; Colombier, Marie-Laure; Nassif, Nadine
作者单位:Universite PSL; College de France; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Paris Cite; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Ecole Normale Superieure de Lyon (ENS de LYON); Institut Universitaire de France; Universite Paris Cite; Assistance Publique Hopitaux Paris (APHP); Hopital Universitaire Bichat-Claude Bernard - APHP; University of Sevilla; Consejo Superior de Investigaciones Cientificas (CSIC); Instituto de Ciencia de Materiales de Sevilla (ICMS-CSIC)
摘要:Autologous bone (AB) is the gold standard for bone-replacement surgeries1, despite its limited availability and the need for an extra surgical site. Traditionally, competitive biomaterials for bone repair have focused on mimicking the mineral aspect of bone, as evidenced by the widespread clinical use of bioactive ceramics2. However, AB also exhibits hierarchical organic structures that might substantially affect bone regeneration. Here, using a range of cell-free biomimetic-collagen-based mat...
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作者:Wissa, Aimy A.
作者单位:Princeton University