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作者：Seung, H. Sebastian
作者单位：Princeton University; Princeton University
摘要：As connectomics advances, it will become commonplace to know far more about the structure of a nervous system than about its function. The starting point for many investigations will become neuronal wiring diagrams, which will be interpreted to make theoretical predictions about function. Here I demonstrate this emerging approach with the Drosophila optic lobe, analysing its structure to predict that three Dm3 (refs. 1-4) and three TmY (refs. 2,4) cell types are part of a circuit that serves t...
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作者：Devineni, Anita V.
作者单位：Emory University
摘要：Neuroscientists have reconstructed the first complete wiring map of the fruit-fly brain, including 140,000 neurons and more than 50 million connections. This resource has already begun to revolutionize the field.
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作者：Remmel, Ariana
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作者：Lambert, Fabrice
作者单位：Pontificia Universidad Catolica de Chile
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作者：Li, Changchao; Liu, Jian; Rillig, Matthias C.; Bank, Michael S.; Fantke, Peter; Zhu, Dong; Zhu, Yong-Guan; Jin, Ling N.
作者单位：Hong Kong Polytechnic University; Shandong University; Free University of Berlin; Institute of Marine Research - Norway; University of Massachusetts System; University of Massachusetts Amherst; Chinese Academy of Sciences; Institute of Urban Environment, CAS; Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS; Chinese Academy of Sciences; Institute of Urban Environment, CAS; Hong Kong Polytechnic University; Hong Kong Polytechnic University; City University of Hong Kong
摘要：Pathogenic viruses and antibiotic-resistant bacteria thrive on plastic. The biohazard risks of this 'plastisphere' shouldn't be overlooked in efforts to tackle the pollution crisis.
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作者：Pearson, Helen
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作者：[Anonymous]
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作者：Marderstein, Andrew R.; De Zuani, Marco; Moeller, Rebecca; Bezney, Jon; Padhi, Evin M.; Wong, Shuo; Coorens, Tim H. H.; Xie, Yilin; Xue, Haoliang; Montgomery, Stephen B.; Cvejic, Ana
作者单位：Stanford University; University of Cambridge; University of Cambridge; Wellcome Trust Sanger Institute; University of Copenhagen; Stanford University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Stanford University
摘要：Down syndrome predisposes individuals to haematological abnormalities, such as increased number of erythrocytes and leukaemia in a process that is initiated before birth and is not entirely understood(1-3). Here, to understand dysregulated haematopoiesis in Down syndrome, we integrated single-cell transcriptomics of over 1.1 million cells with chromatin accessibility and spatial transcriptomics datasets using human fetal liver and bone marrow samples from 3 fetuses with disomy and 15 fetuses w...
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作者：Haeberle, Maximilian; Neumayer, Nadine; Seth, Anil; Bellini, Andrea; Libralato, Mattia; Baumgardt, Holger; Whitaker, Matthew; Dumont, Antoine; Alfaro-Cuello, Mayte; Anderson, Jay; Clontz, Callie; Kacharov, Nikolay; Kamann, Sebastian; Feldmeier-Krause, Anja; Milone, Antonino; Nitschai, Maria Selina; Pechetti, Renuka; van de Ven, Glenn
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作者：Garner, Dustin; Kind, Emil; Lai, Jennifer Yuet Ha; Nern, Aljoscha; Zhao, Arthur; Houghton, Lucy; Sancer, Gizem; Wolff, Tanya; Rubin, Gerald M.; Wernet, Mathias F.; Kim, Sung Soo
作者单位：University of California System; University of California Santa Barbara; Free University of Berlin; Howard Hughes Medical Institute; Yale University; University of California System; University of California Santa Barbara; University of California System; University of California Santa Barbara
摘要：Many animals use visual information to navigate1-4, but how such information is encoded and integrated by the navigation system remains incompletely understood. In Drosophila melanogaster, EPG neurons in the central complex compute the heading direction5 by integrating visual input from ER neurons6-12, which are part of the anterior visual pathway (AVP)10,13-16. Here we densely reconstruct all neurons in the AVP using electron-microscopy data17. The AVP comprises four neuropils, sequentially l...
