2024

最新文章

• Unevidenced biodiversity claim should be abandoned - but biodiversity can be counted AI翻译
  作者：Naidoo, Robin; Loucks, Colby
  作者单位：World Wildlife Fund
• Synthesis of non-canonical amino acids through dehydrogenative tailoring AI翻译
  作者：Gu, Xin; Zhang, Yu-An; Zhang, Shuo; Wang, Leon; Ye, Xiyun; Occhialini, Gino; Barbour, Jonah; Pentelute, Bradley L.; Wendlandt, Alison E.
  作者单位：Massachusetts Institute of Technology (MIT)
  摘要：Amino acids are essential building blocks in biology and chemistry. Whereas nature relies on a small number of amino acid structures, chemists desire access to a vast range of structurally diverse analogues1-3. The selective modification of amino acid side-chain residues represents an efficient strategy to access non-canonical derivatives of value in chemistry and biology. While semisynthetic methods leveraging the functional groups found in polar and aromatic amino acids have been extensively...
• Author Correction: Possible shift in controls of the tropical Pacific surface warming pattern AI翻译
  作者：Watanabe, Masahiro; Kang, Sarah M.; Collins, Matthew; Hwang, Yen-Ting; McGregor, Shayne; Stuecker, Malte F.
  作者单位：University of Tokyo; Max Planck Society; University of Exeter; National Taiwan University; Monash University; University of Hawaii System; University of Hawaii Manoa; University of Hawaii System; University of Hawaii Manoa
• DNA methylation controls stemness of astrocytes in health and ischaemia AI翻译
  作者：Kremer, Lukas P. M.; Cerrizuela, Santiago; El-Sammak, Hadil; Al Shukairi, Mohammad Eid; Ellinger, Tobias; Straub, Jannes; Korkmaz, Aylin; Volk, Katrin; Brunken, Jan; Kleber, Susanne; Anders, Simon; Martin-Villalba, Ana
  作者单位：Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg
  摘要：Astrocytes are the most abundant cell type in the mammalian brain and provide structural and metabolic support to neurons, regulate synapses and become reactive after injury and disease. However, a small subset of astrocytes settles in specialized areas of the adult brain where these astrocytes instead actively generate differentiated neuronal and glial progeny and are therefore referred to as neural stem cells1-3. Common parenchymal astrocytes and quiescent neural stem cells share similar tra...
• Train fieldwork leaders for emergencies AI翻译
  作者：Boon, Sarah
• The Neuroscience AI翻译
  作者：Crew, Bec
• Highly dynamic gamma-ray emissions are common in tropical thunderclouds AI翻译
  作者：Marisaldi, M.; Ostgaard, N.; Mezentsev, A.; Lang, T.; Grove, J. E.; Shy, D.; Heymsfield, G. M.; Krehbiel, P.; Thomas, R. J.; Stanley, M.; Sarria, D.; Schultz, C.; Blakeslee, R.; Quick, M. G.; Christian, H.; Adams, I.; Kroodsma, R.; Lehtinen, N.; Ullaland, K.; Yang, S.; Qureshi, B. Hasan; Sondergaard, J.; Husa, B.; Walker, D.; Bateman, M.; Mach, D.; Cummer, S.; Pazos, M.; Pu, Y.; Bitzer, P.; Fullekrug, M.; Cohen, M.; Montanya, J.; Younes, C.; van der Velde, O.; Roncancio, J. A.; Lopez, J. A.; Urbani, M.; Santos, A.
  作者单位：University of Bergen; Istituto Nazionale Astrofisica (INAF); National Aeronautics & Space Administration (NASA); NASA Marshall Space Flight Center; United States Department of Defense; United States Navy; United States Naval Research Laboratory; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; New Mexico Institute of Mining Technology; University of Alabama System; University of Alabama Huntsville; Universities Space Research Association (USRA); Duke University; Universidad Nacional Autonoma de Mexico; University of Bath; University System of Georgia; Georgia Institute of Technology; Universitat Politecnica de Catalunya; Universidad Nacional de Colombia
  摘要：Thunderstorms emit fluxes of gamma rays known as gamma-ray glows1,2, sporadically observed by aircraft1,3-7, balloons8-11 and from the ground12-18. Observations report increased gamma-ray emissions by tens of percent up to two orders of magnitude above the background, sometimes abruptly terminated by lightning discharges1,3-5. Glows are produced by the acceleration of energetic electrons in high-electric-field regions within thunderclouds8 and contribute to charge dissipation3. Glows had been ...
• The global brainstorm AI翻译
  作者：Crow, James Mitchell
• Jordan's green-energy vision requires refinement AI翻译
  作者：Hussein, Hussam; Khasawneh, Hussam
  作者单位：University of Oxford
• A Drosophila computational brain model reveals sensorimotor processing AI翻译
  作者：Shiu, Philip K.; Sterne, Gabriella R.; Spiller, Nico; Franconville, Romain; Sandoval, Andrea; Zhou, Joie; Simha, Neha; Kang, Chan Hyuk; Yu, Seongbong; Kim, Jinseop S.; Dorkenwald, Sven; Matsliah, Arie; Schlegel, Philipp; Yu, Szi-chieh; McKellar, Claire E.; Sterling, Amy; Costa, Marta; Eichler, Katharina; Bates, Alexander Shakeel; Eckstein, Nils; Funke, Jan; Jefferis, Gregory S. X. E.; Murthy, Mala; Bidaye, Salil S.; Hampel, Stefanie; Seeds, Andrew M.; Scott, Kristin
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of Rochester; Max Planck Society; Sungkyunkwan University (SKKU); Princeton University; Princeton University; University of Cambridge; MRC Laboratory Molecular Biology; University of Oxford; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Harvard University; Harvard Medical School; University of Puerto Rico; University of Puerto Rico Medical Sciences Campus
  摘要：The recent assembly of the adult Drosophila melanogaster central brain connectome, containing more than 125,000 neurons and 50 million synaptic connections, provides a template for examining sensory processing throughout the brain(1,2). Here we create a leaky integrate-and-fire computational model of the entire Drosophila brain, on the basis of neural connectivity and neurotransmitter identity3, to study circuit properties of feeding and grooming behaviours. We show that activation of sugar-se...