2024

最新文章

• High-temperature 205Tl decay clarifies 205Pb dating in early Solar System AI翻译
  作者：Leckenby, Guy; Sidhu, Ragandeep Singh; Chen, Rui Jiu; Mancino, Riccardo; Szanyi, Balazs; Bai, Mei; Battino, Umberto; Blaum, Klaus; Brandau, Carsten; Cristallo, Sergio; Dickel, Timo; Dillmann, Iris; Dmytriiev, Dmytro; Faestermann, Thomas; Forstner, Oliver; Franczak, Bernhard; Geissel, Hans; Gernhaeuser, Roman; Glorius, Jan; Griffin, Chris; Gumberidze, Alexandre; Haettner, Emma; Hillenbrand, Pierre-Michel; Karakas, Amanda; Kaur, Tejpreet; Korten, Wolfram; Kozhuharov, Christophor; Kuzminchuk, Natalia; Langanke, Karlheinz; Litvinov, Sergey; Litvinov, Yuri A.; Lugaro, Maria; Martinez-Pinedo, Gabriel; Menz, Esther; Meyer, Bradley; Morgenroth, Tino; Neff, Thomas; Nociforo, Chiara; Petridis, Nikolaos; Pignatari, Marco; Popp, Ulrich; Purushothaman, Sivaji; Reifarth, Rene; Sanjari, Shahab; Scheidenberger, Christoph; Spillmann, Uwe; Steck, Markus; Stoehlker, Thomas; Tanaka, Yoshiki K.; Trassinelli, Martino; Trotsenko, Sergiy; Varga, Laszlo; Vescovi, Diego; Wang, Meng; Weick, Helmut; Yaguee Lopez, Andres; Yamaguchi, Takayuki; Zhang, Yuhu; Zhao, Jianwei
  作者单位：University of British Columbia; University of British Columbia; Helmholtz Association; GSI Helmholtz-Center for Heavy Ion Research; University of Edinburgh; Max Planck Society; Chinese Academy of Sciences; Institute of Modern Physics, CAS; Technical University of Darmstadt; Szeged University; HUN-REN; HUN-REN Research Centre for Astronomy & Earth Sciences; Konkoly Thege Miklos Astronomical Institute; University of Hull; Istituto Nazionale Astrofisica (INAF); Justus Liebig University Giessen; Istituto Nazionale Astrofisica (INAF); Istituto Nazionale di Fisica Nucleare (INFN); Justus Liebig University Giessen; University of Victoria; Helmholtz Association; Deutsches Elektronen-Synchrotron (DESY); Technical University of Munich; Friedrich Schiller University of Jena; Monash University; University of Tokyo; Panjab University; CEA; Universite Paris Saclay; Helmholtz Association; GSI Helmholtz-Center for Heavy Ion Research; Eotvos Lorand University; Clemson University; Goethe University Frankfurt; United States Department of Energy (DOE); Los Alamos National Laboratory; Helmholtz Association; GSI Helmholtz-Center for Heavy Ion Research; RIKEN; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Saitama University; Charles University Prague
  摘要：Radioactive nuclei with lifetimes on the order of millions of years can reveal the formation history of the Sun and active nucleosynthesis occurring at the time and place of its birth1,2. Among such nuclei whose decay signatures are found in the oldest meteorites, 205Pb is a powerful example, as it is produced exclusively by slow neutron captures (the s process), with most being synthesized in asymptotic giant branch (AGB) stars3-5. However, making accurate abundance predictions for 205Pb has ...
• Mechanisms of odour discrimination revealed AI翻译
  作者：Naressi, Rafaella G.; Malnic, Bettina
  作者单位：Universidade de Sao Paulo
  摘要：How do odorant receptors in the human nose recognize a wide variety of scent molecules? The structures of engineered versions of these receptors finally provide much-needed answers to this fundamental question.
• Grass-roots grant-writing approaches can help researchers at small institutions to succeed AI翻译
  作者：Wells, Sarah
• To boost science, the growing BRICS group must embrace inclusion and transparency AI翻译
  作者：[Anonymous]
• Quantifying constraint in the human mitochondrial genome AI翻译
  作者：Lake, Nicole J.; Ma, Kaiyue; Liu, Wei; Battle, Stephanie L.; Laricchia, Kristen M.; Tiao, Grace; Puiu, Daniela; Ng, Kenneth K.; Cohen, Justin; Compton, Alison G.; Cowie, Shannon; Christodoulou, John; Thorburn, David R.; Zhao, Hongyu; Arking, Dan E.; Sunyaev, Shamil R.; Lek, Monkol
  作者单位：Yale University; Murdoch Children's Research Institute; Royal Children's Hospital Melbourne; Yale University; Johns Hopkins University; University System of Maryland; Bowie State University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Johns Hopkins University; University of Melbourne; Murdoch Children's Research Institute; Victorian Clinical Genetics Services; Royal Children's Hospital Melbourne; Yale University; Harvard University; Harvard Medical School; Harvard University; Harvard Medical School; Harvard University; Harvard Medical School
  摘要：Mitochondrial DNA (mtDNA) has an important yet often overlooked role in health and disease. Constraint models quantify the removal of deleterious variation from the population by selection and represent powerful tools for identifying genetic variation that underlies human phenotypes1-4. However, nuclear constraint models are not applicable to mtDNA, owing to its distinct features. Here we describe the development of a mitochondrial genome constraint model and its application to the Genome Aggr...
• Robotic exoskeleton adapts to changes in leg movements in real time AI翻译
  作者：Kim, Myunghee; Major, Matthew J.
  作者单位：University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; Northwestern University; Feinberg School of Medicine; US Department of Veterans Affairs; Veterans Health Administration (VHA); Jesse Brown VA Medical Center; US Department of Veterans Affairs; Veterans Health Administration (VHA); Jesse Brown VA Medical Center
  摘要：Wearable robots that assist leg movements could transform the lives of people with reduced mobility - but only if the devices can adapt in real time to support a vast range of human activities. Machine learning provides a way forward.
• The quest to build bionic limbs that feel like the real thing AI翻译
  作者：Schwaller, Fred
• Ignoring journal metrics on CVs is an act of privilege AI翻译
  作者：Souza-Neto, Valerio
  作者单位：Griffith University
• No hearing aids needed: bats' ears stay keen well into old age AI翻译
  作者：[Anonymous]
• Temporally distinct 3D multi-omic dynamics in the developing human brain AI翻译
  作者：Heffel, Matthew G.; Zhou, Jingtian; Zhang, Yi; Lee, Dong-Sung; Hou, Kangcheng; Pastor-Alonso, Oier; Abuhanna, Kevin D.; Galasso, Joseph; Kern, Colin; Tai, Chu-Yi; Garcia-Padilla, Carlos; Nafisi, Mahsa; Zhou, Yi; Schmitt, Anthony D.; Li, Terence; Haeussler, Maximilian; Wick, Brittney; Zhang, Martin Jinye; Xie, Fangming; Ziffra, Ryan S.; Mukamel, Eran A.; Eskin, Eleazar; Nowakowski, Tomasz J.; Dixon, Jesse R.; Pasaniuc, Bogdan; Ecker, Joseph R.; Zhu, Quan; Bintu, Bogdan; Paredes, Mercedes F.; Luo, Chongyuan
  作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Salk Institute; University of California System; University of California San Diego; Seoul National University (SNU); Seoul National University (SNU); University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California San Francisco; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California Santa Cruz; Carnegie Mellon University; Harvard University; Harvard T.H. Chan School of Public Health; University of California System; University of California San Diego; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California Los Angeles; Salk Institute; Howard Hughes Medical Institute; Salk Institute; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：The human hippocampus and prefrontal cortex play critical roles in learning and cognition1,2, yet the dynamic molecular characteristics of their development remain enigmatic. Here we investigated the epigenomic and three-dimensional chromatin conformational reorganization during the development of the hippocampus and prefrontal cortex, using more than 53,000 joint single-nucleus profiles of chromatin conformation and DNA methylation generated by single-nucleus methyl-3C sequencing (snm3C-seq3)...