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作者：Robin, Marc; Mouloungui, Elodie; Castillo Dali, Gabriel; Wang, Yan; Saffar, Jean-Louis; Pavon-Djavid, Graciela; Divoux, Thibaut; Manneville, Sebastien; Behr, Luc; Cardi, Delphine; Choudat, Laurence; Giraud-Guille, Marie-Madeleine; Meddahi-Pelle, Anne; Baudimont, Fannie; Colombier, Marie-Laure; Nassif, Nadine
作者单位：Universite PSL; College de France; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Paris Cite; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Ecole Normale Superieure de Lyon (ENS de LYON); Institut Universitaire de France; Universite Paris Cite; Assistance Publique Hopitaux Paris (APHP); Hopital Universitaire Bichat-Claude Bernard - APHP; University of Sevilla; Consejo Superior de Investigaciones Cientificas (CSIC); Instituto de Ciencia de Materiales de Sevilla (ICMS-CSIC)
摘要：Autologous bone (AB) is the gold standard for bone-replacement surgeries1, despite its limited availability and the need for an extra surgical site. Traditionally, competitive biomaterials for bone repair have focused on mimicking the mineral aspect of bone, as evidenced by the widespread clinical use of bioactive ceramics2. However, AB also exhibits hierarchical organic structures that might substantially affect bone regeneration. Here, using a range of cell-free biomimetic-collagen-based mat...
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作者：Wissa, Aimy A.
作者单位：Princeton University
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作者：Reyes, Raphael A.; Raghavan, Sai Sundar Rajan; Hurlburt, Nicholas K.; Introini, Viola; Bol, Sebastiaan; Kana, Ikhlaq Hussain; Jensen, Rasmus W.; Martinez-Scholze, Elizabeth; Gestal-Mato, Maria; Lopez-Gutierrez, Borja; Sanz, Silvia; Bancells, Cristina; Fernandez-Quintero, Monica Lisa; Loeffler, Johannes R.; Ferguson, James Alexander; Lee, Wen-Hsin; Martin, Greg Michael; Theander, Thor G.; Lusingu, John P. A.; Minja, Daniel T. R.; Ssewanyana, Isaac; Feeney, Margaret E.; Greenhouse, Bryan; Ward, Andrew B.; Bernabeu, Maria; Pancera, Marie; Turner, Louise; Bunnik, Evelien M.; Lavstsen, Thomas
作者单位：University of Texas System; University of Texas at San Antonio; University of Copenhagen; Scripps Research Institute; Fred Hutchinson Cancer Center; National Institute of Medical Research; University of California System; University of California San Francisco; University of California System; University of California San Francisco
摘要：Malaria pathology is driven by the accumulation of Plasmodium falciparum-infected erythrocytes in microvessels1. This process is mediated by the polymorphic erythrocyte membrane protein 1 (PfEMP1) adhesion proteins of the parasite. A subset of PfEMP1 variants that bind to human endothelial protein C receptor (EPCR) through their CIDR alpha 1 domains is responsible for severe malaria pathogenesis2. A longstanding question is whether individual antibodies can recognize the large repertoire of ci...
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作者：[Anonymous]
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作者：[Anonymous]
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作者：Tan, Qing-Hua; Daddi, Emanuele; Magnelli, Benjamin; Correa, Camila A.; Bournaud, Frederic; Adscheid, Sylvia; Zhang, Shao-Bo; Elbaz, David; Gomez-Guijarro, Carlos; Kalita, Boris S.; Liu, Daizhong; Liu, Zhaoxuan; Pety, Jerome; Puglisi, Annagrazia; Schinnerer, Eva; Silverman, John D.; Valentino, Francesco
作者单位：Purple Mountain Observatory, CAS; Chinese Academy of Sciences; Nanjing Institute of Astronomical Optics & Technology, NAOC, CAS; CEA; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Universite Paris Saclay; University of Bonn; University of Tokyo; University of Tokyo; Peking University; University of Tokyo; Universite PSL; Observatoire de Paris; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); University of Southampton; Durham University; Max Planck Society; Johns Hopkins University; European Southern Observatory
摘要：Most stars in today's Universe reside within spheroids, which are bulges of spiral galaxies and elliptical galaxies1,2. Their formation is still an unsolved problem3, 4-5. Infrared/submillimetre-bright galaxies at high redshifts6 have long been suspected to be related to spheroid formation7, 8, 9, 10, 11-12. Proving this connection has been hampered so far by heavy dust obscuration when focusing on their stellar emission13, 14-15 or by methodologies and limited signal-to-noise ratios when look...
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作者：Swift, Joseph; Luginbuehl, Leonie H.; Hua, Lei; Schreier, Tina B.; Donald, Ruth M.; Stanley, Susan; Wang, Na; Lee, Travis A.; Nery, Joseph R.; Ecker, Joseph R.; Hibberd, Julian M.
作者单位：Salk Institute; University of Cambridge; Salk Institute; Salk Institute; Howard Hughes Medical Institute; University of Oxford
摘要：C4 photosynthesis is used by the most productive plants on the planet, and compared with the ancestral C3 pathway, it confers a 50% increase in efficiency1. In more than 60 C4 lineages, CO2 fixation is compartmentalized between tissues, and bundle-sheath cells become photosynthetically activated2. How the bundle sheath acquires this alternate identity that allows efficient photosynthesis is unclear. Here we show that changes to bundle-sheath gene expression in C4 leaves are associated with the...
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作者：Cook, Kristen L.
作者单位：Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA)
摘要：Climate change and urbanization are exacerbating the effects of flooding. A close look at a Nepalese river reveals that efforts to reduce the impact of floods must consider the geomorphic changes that occur during these extreme events.
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作者：Kudiabor, Helena
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作者：Gao, Teng; Sankaran, Vijay G.
作者单位：Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
摘要：Gene-edited stem cells can be used in regenerative therapies to treat diverse genetic diseases. Tracking the output of these cells over time reveals a commitment to lineages that meet disease-specific needs.
